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Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
Pediatric Drugs ( IF 3.7 ) Pub Date : 2023-05-04 , DOI: 10.1007/s40272-023-00566-x
Hadi Sahrai 1 , Mahdi Hemmati-Ghavshough 1 , Marzieh Shahrabi 2 , Amir Hossein Jafari-Rouhi 3 , Mohammad Solduzian 4
Affiliation  

In addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have shown that starting anticoagulant prophylaxis, which contributes to decreased thrombotic events, is dependent on the patient's condition and D-dimer levels. However, further studies on pediatric populations are needed to establish the role of anticoagulants in children with this condition.



中文翻译:

儿科中与 COVID-19 相关的凝血病的血栓预防:叙述性回顾

除了损害呼吸系统外,COVID-19 还会影响多个器官。儿童可能会出现一种特殊的 COVID-19 并发症,称为儿童多系统炎症综合征 (MIS-C),它可能会影响儿童的血管系统并导致体内多种凝血病。通过查阅各种文章收集了有关在这种情况下使用血栓预防的信息。一般来说,免疫系统反应中的不同因素可以触发血栓事件的发生。研究表明,开始抗凝预防有助于减少血栓事件,这取决于患者的病情和 D-二聚体水平。然而,需要对儿科人群进行进一步的研究来确定抗凝剂在患有这种疾病的儿童中的作用。

更新日期:2023-05-05
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