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Avian reovirus: a furious and fast evolving pathogen
Journal of Medical Microbiology ( IF 3 ) Pub Date : 2023-10-06 , DOI: 10.1099/jmm.0.001761
Sofia Egana-Labrin 1 , Andrew J Broadbent 1
Affiliation  

Avian reoviruses (ARVs) have a significant economic impact on the poultry industry, affecting commercial and backyard flocks. Spread feco-orally, or vertically, many do not cause morbidity, but pathogenic strains can contribute to several diseases, including tenosynovitis/arthritis, which is clinically the most significant. The last decade has seen a surge in cases in the US, and due to ongoing evolution, seven genotypic clusters have now been identified. Control efforts include strict biosecurity and vaccination with commercial and autogenous vaccines. Research priorities include improving understanding of pathogenesis and developing new vaccines guided by ongoing molecular and serologic surveillance.

中文翻译:

禽呼肠孤病毒:一种凶猛且快速进化的病原体

禽呼肠孤病毒(ARV)对家禽业具有重大的经济影响,影响商业和后院鸡群。通过粪口或垂直传播,许多不会引起发病,但致病菌株可导致多种疾病,包括临床上最重要的腱鞘炎/关节炎。过去十年,美国的病例激增,由于不断的演变,现已确定了七个基因型簇。控制工作包括严格的生物安全以及使用商业疫苗和自体疫苗进行疫苗接种。研究重点包括增进对发病机制的了解以及在持续的分子和血清学监测指导下开发新疫苗。
更新日期:2023-10-07
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