: Gap junction (GJ) is a special cell membrane structure composed of connexin. Connexin is widely distributed and expressed in all tissues except differentiated skeletal muscle, red blood cells, and mature sperm cells, which is related to the occurrence of many genetic diseases due to its mutation. Its function of regulating immune response, cell proliferation, migration, apoptosis, and carcinogenesis makes it a therapeutic target for a variety of diseases. In this paper, the possible mechanism of its action in nervous system-related diseases and treatment are reviewed.

中文翻译：

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间隙连接蛋白及其在神经系统相关疾病中的潜在作用的综述

：间隙连接（GJ）是由连接蛋白组成的特殊细胞膜结构。连接蛋白广泛分布并表达于除分化的骨骼肌、红细胞和成熟精子细胞外的所有组织中，由于其突变与许多遗传性疾病的发生有关。其调节免疫反应、细胞增殖、迁移、凋亡和癌变的功能使其成为多种疾病的治疗靶点。本文就其在神经系统相关疾病中的可能作用机制及治疗进行综述。