Abstract

The reactions in the Cu(OAc)₂⋅H₂O–phytic acid–2,2'-bipyridine (bpy) system in aqueous methanol solutions resulted in the formation of a molecular different-ligand tetranuclear complex [(Cu₄(bpy)₄(PO₄)₂(CO₃)(H₂O)₂]⋅13H₂O (I), the structure of which was established from the X-ray diffraction data (CCDC no. 2262998). The molecule of complex I contains four non-equivalent Cu²⁺ cations, coordinating each two phosphate anions (\({\text{PO}}_{4}^{{3 - }}\) remaining after the transformation of the phytate ring), four neutral bpy molecules, two water molecules, and one carbonate anion (\({\text{CO}}_{3}^{{2 - }}\)). The presence of a large number of solvate water molecules in the outer coordination sphere gives rise to a hydrogen-bonded framework involved in stabilization of the crystal packing. Study of the antimycobacterial activity of I against non-pathogenic Mycolicibacterium smegmatis strain revealed high biological efficacy.

中文翻译：

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混合配体配合物 [Cu4(bpy)4(PO4)2(CO3)(H2O)2]：合成、晶体结构和生物学性质

摘要

Cu(OAc) 中的反应₂⋅H₂O-植酸-2,2'-联吡啶（bpy）体系在甲醇水溶液中形成分子不同配体四核络合物[(Cu_{4< /span>})(H₃(CO₂)₄(PO₄(bpy)O)₂]⋅13H₂菌株的抗分枝杆菌活性研究显示出较高的生物学功效。耻垢分枝杆菌对非致病性I). 外部配位层中大量溶剂化水分子的存在产生了参与稳定晶体堆积的氢键框架。 \({\text{CO}}_{3}^{{2 - }} \) 后剩余植酸环的转变）、四个中性 bpy 分子、两个水分子和一个碳酸根阴离子 (\({\text{PO}}_{4}^{{3 - }}\)阳离子，配位每两个磷酸根阴离子 (²⁺分子含有四个非等价的CuI)，其结构是根据X射线衍射数据确定的（CCDC no. 2262998）。配合物IO (