In the modern interventional treatment of degenerated saphenous vein grafts, the use of both bare metal and drug eluting stents have been described so far. Drug eluting balloons have been increasingly used in cases of in-stent restenosis and to some extent de novo stenosis of native coronary vessels. Based on pure logic approach, the use of drug eluting balloons in in-stent restenosis of the saphenous vein graft may be of great interest. Still, few high-quality data on this subject exist and no general recommendations can be made. This paper illustrates a typical case of a symptomatic late in-stent restenosis of a saphenous vein graft occurred 15 months after a percutaneous coronary intervention with implantation of two drug eluting stents. Intravascular ultrasound revealed a mixture of stent underexpansion and severe neointima. This was treated safely with a prolonged high pressure balloon dilatation followed by dilatation with a drug eluting balloon. The primary result was very good. During the intervention the patient remained asymptomatic and was discharged the next day on dual anti-platelet therapy. During the 10-month follow-up the patient remained asymptomatic. This case demonstrates the usefulness and clinical safety of drug eluting balloons in treating in-stent restenosis in the saphenous vein grafts.

在退变隐静脉移植物的现代介入治疗中，迄今为止已经描述了裸金属支架和药物洗脱支架的使用。药物洗脱球囊越来越多地用于支架内再狭窄以及一定程度的原生冠状血管从头狭窄的情况。基于纯逻辑方法，在隐静脉移植物支架内再狭窄中使用药物洗脱球囊可能会引起人们的极大兴趣。尽管如此，关于这个主题的高质量数据仍然很少，也无法提出一般性建议。本文阐述了植入两个药物洗脱支架的经皮冠状动脉介入治疗 15 个月后发生的有症状的隐静脉移植物晚期支架内再狭窄的典型病例。血管内超声显示支架扩张不足和严重的新内膜混合。通过长时间的高压球囊扩张，然后用药物洗脱球囊扩张来安全地治疗这一问题。初步结果非常好。在干预期间，患者保持无症状，并于第二天出院接受双重抗血小板治疗。在 10 个月的随访期间，患者一直没有出现任何症状。该病例证明了药物洗脱球囊在治疗隐静脉移植物支架内再狭窄方面的实用性和临床安全性。