We investigated whether retrograde amnesia for the stress-induced impairment of extinction retrieval shares similar characteristics with original acquisition memories. The first experiment demonstrated that cycloheximide administered shortly after a single restraint stress session alleviated the impairment of extinction retrieval but not when administered following a longer delay (i.e., the amnesia for stress is time-dependent). A second experiment showed that the retrograde amnesia for stress could be alleviated by a second brief exposure to the stressor. These results demonstrating that amnesia for stress shares characteristics similar to original memories are explained using a retrieval-based memory integration model of retrograde amnesia.

中文翻译：

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对压力引起的灭绝损伤的逆行性遗忘：依赖于时间并且不会被遗忘

我们研究了压力引起的消退记忆损伤的逆行性遗忘是否与原始习得记忆具有相似的特征。第一个实验表明，在单次约束应激训练后不久施用放线菌酮可以减轻消退恢复的损害，但在较长时间延迟后施用则不然（即，对压力的遗忘是时间依赖性的）。第二个实验表明，第二次短暂接触压力源可以缓解对压力的逆行性遗忘。这些结果表明，压力遗忘症具有与原始记忆相似的特征，可以使用基于检索的逆行性遗忘症记忆整合模型来解释。