Background: Nanocomposite glycerohydrogels based on biocompatible elementcontaining glycerolates are of practicular interest for biomedical applications. Objective: Using two biocompatible precursors, silicon and iron glycerolates, a new bioactive nanocomposite silicon‒iron glycerolates hydrogel was obtained by sol-gel method. Methods: The composition and structural features of the hydrogel were studied using a complex of modern analytical techniques, including TEM, XRD, and AES. On the example of experimental animals hemostatic activity of the hydrogel was studied, as well as primary toxicological studies were carried out. method: The composition and structural features of the gel were studied using a complex of modern analytical methods, including TEM, XRD, and atomic emission spectroscopy. On the example of experimental animals its hemostatic activity was studied, as well as primary toxicological studies were carried out. Results: The composition of dispersed phase and dispersion medium of silicon‒iron glycerolates hydrogel was determined. The structural features of hydrogel were revealed and its structure model was proposed. It was shown that silcon-iron glycerolates hydrogel is nontoxic, and exhibits pronounced hemostatic activity. result: The composition of dispersed phase and dispersion medium of silicon‒iron glycerolates hydrogel was determined, its structural features were revealed and a structure model was proposed. It was shown that silicon–iron glycerolates hydrogel is nontoxic, and exhibits pronounced hemostatic activity. Conclusion: Silicon-iron glycerolates hydrogel is a potential hemostatic agent for topical application in medical and veterinary practice.

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单甘油铁（III）作为新型生物相容性前体用于合成生物活性纳米复合甘油水凝胶

背景：基于含有生物相容性元素的甘油酯的纳米复合甘油水凝胶对于生物医学应用具有实际意义。目的：利用两种生物相容性前体——甘油硅酸和甘油酸铁，通过溶胶-凝胶法获得一种新型生物活性纳米复合硅铁甘油酸水凝胶。方法：使用 TEM、XRD 和 AES 等现代分析技术综合研究水凝胶的组成和结构特征。以实验动物为例，研究了水凝胶的止血活性，并进行了初步毒理学研究。方法：使用一系列现代分析方法（包括 TEM、XRD 和原子发射光谱法）研究了凝胶的组成和结构特征。以实验动物为例，研究了其止血活性，并进行了初步毒理学研究。结果：确定了硅铁甘油酸盐水凝胶的分散相和分散介质的组成。揭示了水凝胶的结构特征并提出了其结构模型。结果表明，硅铁甘油酯水凝胶无毒，并具有显着的止血活性。结果：确定了硅铁甘油酯水凝胶分散相和分散介质的组成，揭示了其结构特征，并提出了结构模型。结果表明，硅铁甘油酯水凝胶无毒，并具有显着的止血活性。结论：硅铁甘油酯水凝胶是一种在医疗和兽医实践中局部应用的潜在止血剂。