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Inflammatory/juvenile-like polyps in neurofibromatosis type 1 associated with epithelial dysplasia
Virchows Archiv ( IF 3.5 ) Pub Date : 2024-02-24 , DOI: 10.1007/s00428-024-03769-w
Diana Enea , Xavier Dray , Erell Guillerm , Antoine Guilloux , Matthieu Yver , Pascale Cervera , Magali Svrcek

The term “juvenile-like (inflammatory/hyperplastic) mucosal polyps” (JLIHMP) has been recently introduced to describe a spectrum of polypoid lesions in patients with neurofibromatosis type 1 (NF-1). Due to the scarce number of reported cases and histopathological similarities with entities such as sporadic/syndromic juvenile polyps or inflammatory fibroid polyps, this entity remains a subject of debate. We describe herein a case of multiple JLIHMPs in a patient with NF-1, and we document the presence of low-grade dysplasia within one of these polyps.



中文翻译:

与上皮发育不良相关的 1 型神经纤维瘤病中的炎症/幼年样息肉

最近引入术语“幼年型(炎症/增生性)粘膜息肉”(JLIHMP)来描述 1 型神经纤维瘤病(NF-1)患者的一系列息肉样病变。由于报告病例数量稀少,且组织病理学与散发性/综合征性幼年息肉或炎性纤维瘤息肉等实体相似,因此该实体仍然是一个争论的话题。我们在此描述了一名 NF-1 患者体内存在多个 JLIHMP 的病例,并且我们记录了其中一个息肉内存在低度不典型增生。

更新日期:2024-02-24
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