Abstract

The purpose of the work was to study the influence of natural polysaccharides—arabinogalactan, galactomannan, and carrageenan—on the growth of Klebsiella pneumoniae strains. It was found that carrageenan, especially in high concentrations, most effectively stimulated the growth of these microorganisms. A dependence of the effect of galactomannan on the concentration used was discovered: an inhibitory effect was detected in high doses and a stimulating effect in low doses. Arabinogalactan inhibited the growth of Klebsiella pneumoniae, which could be due to phenolic impurities (bioflavonoids), the presence of which is typical of this polysaccharide. Moreover, this polysaccharide at a concentration of 0.1 mg/mL completely blocked the growth of the studied microbial strains, which can be explained by the antibacterial effect of flavonoids.

中文翻译：

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天然多糖对体外肺炎克雷伯菌种群密度的影响

摘要

这项工作的目的是研究天然多糖——阿拉伯半乳聚糖、半乳甘露聚糖和角叉菜胶——对肺炎克雷伯菌菌株生长的影响。研究发现，卡拉胶，尤其是高浓度的卡拉胶，最有效地刺激这些微生物的生长。发现半乳甘露聚糖的作用与所用浓度的依赖性：在高剂量下检测到抑制作用，在低剂量下检测到刺激作用。阿拉伯半乳聚糖抑制肺炎克雷伯菌的生长，这可能是由于酚类杂质（生物类黄酮）的存在，这种多糖的典型特征是存在酚类杂质。此外，这种浓度为0.1 mg/mL的多糖完全阻断了所研究的微生物菌株的生长，这可以用黄酮类化合物的抗菌作用来解释。