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Preparation of Substituted gem-Dichlorocyclopropanes and 1,3-Dioxacycloalkanes and Their Biological Activity: A Review
Reviews and Advances in Chemistry Pub Date : 2023-12-01 , DOI: 10.1134/s263482762460004x
G. Z. Raskil’dina , A. I. Musin , Yu. G. Borisova , R. M. Sultanova , R. R. Daminev , S. S. Zlotskii

Abstract―

This work generalizes methods for preparation of basic platform compounds, namely, hem-dichlorocyclopropanes and 1,3-dioxacycloalkanes with various substituents. On their basis, the synthesis of carbo- and heterocyclic compounds is carried out, which have herbicidal, cytotoxic, anticoagulant and antiaggregation properties and are of interest in terms of creating new pesticides for dicotyledonous and monocotyledonous plants, drugs that prevent blood clotting or inhibit the development of tumor cells.



中文翻译:

取代偕二氯环丙烷和1,3-二氧杂环烷烃的制备及其生物活性:综述

摘要-

这项工作概括了基本平台化合物的制备方法,即具有各种取代基的 hem-二氯环丙烷和 1,3-二氧杂环烷烃。在此基础上,进行了碳环和杂环化合物的合成,这些化合物具有除草、细胞毒性、抗凝血和抗聚集特性,并且在创造用于双子叶和单子叶植物的新农药、防止血液凝固或抑制血液凝固的药物方面具有重要意义。肿瘤细胞的发育。

更新日期:2023-12-01
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