Abstract

Objectives

There is a rapidly growing body of research into mindfulness-based interventions (MBIs) for People Experiencing Psychosis. This study aimed to examine the feasibility of a novel, 6-week 1:1 MBI, as well as the feasibility of the assessment and analysis of between-session practice and metacognitive beliefs as predictors of Quality of Life (QoL) outcomes.

Method

A case series design was used. Eight participants were recruited, with seven completers. The primary outcome, QoL, was assessed up to four times per week, with additional outcomes taken weekly, pre-post, and pre-mid-post. Multilevel modelling was used to examine predictors.

Results

The methods and intervention were feasible. However, most participants preferred shorter, 30-min appointments with one mindfulness practice. Between-session practice varied significantly (0–220 min total), with three participants completing no between-session practice. Pre- to mid-intervention improvement in metacognitive beliefs was lost at post-intervention assessment. Non-significant trends of improvement were noted in most outcomes.

Conclusions

A full-scale trial is recommended to assess the intervention and predictors, with adjustment of intervention length and post-intervention assessment suggested. Future research should also further examine metacognitive processes and factors associated with between-session practice adherence for people experiencing psychosis accessing MBIs.

Preregistration

This study was not preregistered. However, detailed study and intervention protocols were created as part of the ethics application, which was followed throughout the study. These documents are available upon request.

中文翻译：

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针对精神病患者的正念干预：一项随机可行性研究

摘要

目标

针对精神病患者的正念干预 (MBI) 的研究正在迅速增长。本研究旨在检验新型 6 周 1:1 MBI 的可行性，以及评估和分析课间练习和元认知信念作为生活质量 (QoL) 结果预测因素的可行性。

方法

采用了表壳系列设计。招募了八名参与者，其中七名完成者。主要结果（生活质量）每周评估最多四次，每周、事前和事中前评估额外结果。使用多级建模来检查预测变量。

结果

方法和干预是可行的。然而，大多数参与者更喜欢较短的 30 分钟约会，进行一次正念练习。课间练习差异很大（总共 0-220 分钟），三名参与者没有完成课间练习。干预前至中期元认知信念的改善在干预后评估中消失了。大多数结果都没有显着的改善趋势。

结论

建议进行全面试验来评估干预措施和预测因素，并建议调整干预长度和干预后评估。未来的研究还应该进一步研究与精神病患者访问 MBI 的疗程间练习依从性相关的元认知过程和因素。

预登记

这项研究没有预先注册。然而，详细的研究和干预方案是作为伦理申请的一部分制定的，并在整个研究过程中遵循。这些文件可根据要求提供。