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Long-term second-generation antipsychotics decreases bone formation and resorption in male patients with schizophrenia Psychopharmacology (IF 3.4) Pub Date : 2024-04-22 Fan Wang, Hui Li, Kaijun Yi, Yan Wu, Qingtao Bian, Baoyan Guo, Xingguang Luo, Yimin Kang, Qi Wu, Qinghe Ma
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A rat model of operant negative reinforcement in opioid-dependent males and females Psychopharmacology (IF 3.4) Pub Date : 2024-04-20 Jonathan J. Chow, Kayla M. Pitts, Jules M. Chabot, Rutsuko Ito, Yavin Shaham
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N-(3-((3-(trifluoromethyl)phenyl)selanyl)prop-2-yn-1-yl) benzamide induces antidepressant-like effect in mice: involvement of the serotonergic system Psychopharmacology (IF 3.4) Pub Date : 2024-04-18 Camila Simões Pires, Marcia Juciele da Rocha, Marcelo Heinemann Presa, Narryman Pinto Zuge, Natália Emanuele Biolosor Kuntz, Benhur Godoi, Cristiani Folharini Bortolatto, César Augusto Brüning
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Teneurin C-terminal associated peptide (TCAP)-1 attenuates the development and expression of naloxone-precipitated morphine withdrawal in male Swiss Webster mice Psychopharmacology (IF 3.4) Pub Date : 2024-04-17 Lauren E. Mueller, Roseanne S. Wexler, David A. Lovejoy, Robert B. Stein, Andrew M. Slee
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Coenzyme Q10 and exercise training reinstate middle cerebral artery occlusion-induced behavioral deficits and hippocampal long-term potentiation suppression in aging rats Psychopharmacology (IF 3.4) Pub Date : 2024-04-17 Kamal Ranjbar, Alireza Komaki, Bayan Fayazi, Ebrahim Zarrinkalam
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Leveraging meta-regression to test if medication effects on cue-induced craving are associated with clinical efficacy Psychopharmacology (IF 3.4) Pub Date : 2024-04-13 Steven J. Nieto, Han Du, Lindsay R. Meredith, Suzanna Donato, Molly Magill, Lara A. Ray
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Dysregulations of amino acid metabolism and lipid metabolism in urine of children and adolescents with major depressive disorder: a case-control study Psychopharmacology (IF 3.4) Pub Date : 2024-04-12 Yuanliang Jiang, Yuping Cai, Teng Teng, Xiaolin Wang, Bangmin Yin, Xuemei Li, Ying Yu, Xueer Liu, Jie Wang, Hongyan Wu, Yuqian He, Zheng-Jiang Zhu, Xinyu Zhou
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5-HT 2A and 5-HT 2C receptor antagonism differentially modulate reinforcement learning and cognitive flexibility: behavioural and computational evidence Psychopharmacology (IF 3.4) Pub Date : 2024-04-10 Mona El- Sayed Hervig, Katharina Zühlsdorff, Sarah F. Olesen, Benjamin Phillips, Tadej Božič, Jeffrey W. Dalley, Rudolf N. Cardinal, Johan Alsiö, Trevor W. Robbins
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Disruption of positive- and negative-feature morphine interoceptive occasion setters by dopamine receptor agonism and antagonism in male and female rats Psychopharmacology (IF 3.4) Pub Date : 2024-04-06 Davin R Peart, Caitlin J Nolan, Adiia P Stone, Mckenna A Williams, Jessica M Karlovcec, Jennifer E Murray
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Novel rat model of gaming disorder: assessment of social reward and sex differences in behavior and c-Fos brain activity Psychopharmacology (IF 3.4) Pub Date : 2024-04-05 Antonino Casile, Marilena Marraudino, Brigitta Bonaldo, Maria Vittoria Micioni Di Bonaventura, Sofia Nasini, Carlo Cifani, Stefano Gotti
Rationale In 2018, the International Classification of Diseases (ICD-11) classified Gaming Disorder (GD) as a mental disorder. GD mainly occurs among adolescents, who, after developing addiction, show psychopathological traits, such as social anxiety, depression, social isolation, and attention deficit. However, the different studies conducted in humans so far show several limitations, such as the
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Impact of aripiprazole discontinuation in remitted major depressive disorder: a randomized placebo-controlled trial Psychopharmacology (IF 3.4) Pub Date : 2024-03-28 Masahiro Takeshima, Akise Umakoshi, Yuki Omori, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo, Yu Itoh, Naoko Ayabe, Kazuo Mishima
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Light Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing Psychopharmacology (IF 3.4) Pub Date : 2024-03-26 Inês Macedo, Tiago O. Paiva, Rita Pasion, Laura Daedelow, Andreas Heinz, Ana Magalhães, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sarah Hohmann, Nathalie Holz, Juliane H. Fröhner
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Stimulus mediation, specificity and impact of menthol in rats trained to discriminate puffs of nicotine e-cigarette aerosol from nicotine-free aerosol Psychopharmacology (IF 3.4) Pub Date : 2024-03-23 Yasmin Alkhlaif, Keith L. Shelton
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Efficacy of probiotic supplements in improving the symptoms of psychosis, anxiety, insomnia, and anorexia due to amphetamine and methamphetamine use: a randomized clinical trial Psychopharmacology (IF 3.4) Pub Date : 2024-03-21
Abstract Rationale Changes in the density and diversity of gut microbiota in chronic use of methamphetamine have been mentioned as contributors to psychotic and anxiety symptoms, sleep problems, and loss of appetite. Objective In this placebo-controlled clinical trial, we investigated the effect of the probiotic Lactobacillus Acidophilus in improving psychiatric symptoms among hospitalized patients
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Preconception opioids interact with mouse strain to alter morphine withdrawal in the next generation Psychopharmacology (IF 3.4) Pub Date : 2024-03-19 Anika Toorie, Claire Davidson Hall, Fair M. Vassoler, Gary Peltz, Elizabeth M. Byrnes
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Preeclampsia as a possible risk factor for memory impairment, anxiety- and depressive-like behavior in offspring Psychopharmacology (IF 3.4) Pub Date : 2024-03-19 Blanca Rubí Vélez-Godínez, Pedro López-Sánchez, Nayeli Páez-Martínez
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The effects of pramipexole on motivational vigour during a saccade task: a placebo-controlled study in healthy adults Psychopharmacology (IF 3.4) Pub Date : 2024-03-18 Sheena K. Au-Yeung, Don Chamith Halahakoon, Alexander Kaltenboeck, Philip Cowen, Michael Browning, Sanjay G Manohar
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Long-term disruption of tissue levels of glutamate and glutamatergic neurotransmission neuromodulators, taurine and kynurenic acid induced by amphetamine Psychopharmacology (IF 3.4) Pub Date : 2024-03-14 Ewa Taracha, Magdalena Czarna, Danuta Turzyńska, Alicja Sobolewska, Piotr Maciejak
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Synergistic use of deep TMS therapy with IV ketamine infusions for major depressive disorder: a pilot study Psychopharmacology (IF 3.4) Pub Date : 2024-03-12 Nathaniel A. Shanok, Sabrina Muzac, Leah Brown, Melissa Barrera, Raul Rodriguez
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Noribogaine acute administration in rats promotes wakefulness and suppresses REM sleep Psychopharmacology (IF 3.4) Pub Date : 2024-03-12 Juan Pedro Castro-Nin, Diego Serantes, Paola Rodriguez, Bruno Gonzalez, Ignacio Carrera, Pablo Torterolo, Joaquín González
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The role of mGluR5 on the therapeutic effects of ketamine in Wistar rats Psychopharmacology (IF 3.4) Pub Date : 2024-03-09
Abstract Rationale Ketamine produces dissociative, psychomimetic, anxiolytic, antidepressant, and anesthetic effects in a dose dependent manner. It has a complex mechanism of action that involve alterations in other glutamate receptors. The metabotropic glutamate receptor 5 (mGluR5) has been investigated in relation to the psychotic and anesthetic properties of ketamine, while its role in mediating
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Operant social self-administration in male CD1 mice Psychopharmacology (IF 3.4) Pub Date : 2024-03-08
Abstract Rationale and Objective We recently introduced a model of operant social reward in which female CD1 mice lever press for access to affiliative social interaction with a cagemate peer mouse of the same sex and strain. Here we determined the generality of the operant social self-administration model to male CD1 mice who, under certain conditions, will lever press to attack a subordinate male
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Knowledge by omission: the significance of omissions in the 5-choice serial reaction time task Psychopharmacology (IF 3.4) Pub Date : 2024-03-06 Caroline Vouillac-Mendoza, Audrey Durand, Serge H. Ahmed, Karine Guillem
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A systematic review and meta-analysis of synthetic cathinone use and psychosis Psychopharmacology (IF 3.4) Pub Date : 2024-03-06 Rishika R. Daswani, Cassandra M. Choles, David D. Kim, Alasdair M. Barr
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Chronic REM sleep deprivation leads to manic- and OCD-related behaviors, and decreases hippocampal BDNF expression in female rats Psychopharmacology (IF 3.4) Pub Date : 2024-03-02 Nahal Abbasi, Yasaman Mirabzadeh, Golnaz Khesali, Zahra Ebrahimkhani, Hanie Karimi, Salar Vaseghi
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Changes in distinct brain systems identified with fMRI during smoking cessation treatment with varenicline: a review Psychopharmacology (IF 3.4) Pub Date : 2024-03-02 Vassilis N. Panagopoulos, Alexis Bailey, George K. Kostopoulos, Andreas A. Ioannides
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Baseline prepulse inhibition dependency of orexin A and REM sleep deprivation Psychopharmacology (IF 3.4) Pub Date : 2024-03-01 Pınar Öz, Osman Kamalı, Hacer Begüm Saka, Ceren Gör, İsmail Tayfun Uzbay
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Neurexin1α knockout in rats causes aberrant social behaviour: relevance for autism and schizophrenia Psychopharmacology (IF 3.4) Pub Date : 2024-02-29 E. J. Marijke Achterberg, Barbara Biemans, Louk J. M. J. Vanderschuren
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The acute effects of cannabis, with and without cannabidiol, on attentional bias to cannabis related cues: a randomised, double-blind, placebo-controlled, cross-over study Psychopharmacology (IF 3.4) Pub Date : 2024-02-28 Daniel Hall, Will Lawn, Shelan Ofori, Katie Trinci, Anya Borissova, Claire Mokrysz, Kat Petrilli, Michael A. P. Bloomfield, Matthew B. Wall, Tom P. Freeman, H. Valerie Curran
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Repeated Δ-9-Tetrahydrocannabinol administration dose dependently increases stablished schedule-induced drinking Psychopharmacology (IF 3.4) Pub Date : 2024-02-28 Esmeralda Fuentes-Verdugo, Ricardo Pellón, Miguel Miguéns
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Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway Psychopharmacology (IF 3.4) Pub Date : 2024-02-27
Abstract Rationale Microglia-mediated neuroinflammation is a vital hallmark in progression of depression, while calcitriol exerts anti-inflammatory effects in the brain. The activation of the P2X7 receptor has an important link to neuroinflammation. However, it is unclear whether calcitriol treatment exerts anti-inflammatory effects in association with P2X7R activation. Objective In this study, we
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Gut microbiota connects the brain and the heart: potential mechanisms and clinical implications Psychopharmacology (IF 3.4) Pub Date : 2024-02-26 Yi Zhang, Kai Huang, Jiahao Duan, Rong Zhao, Ling Yang
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Effects of estrogen on spatial navigation and memory Psychopharmacology (IF 3.4) Pub Date : 2024-02-26 Gina Joue, Tobias Navarro-Schröder, Johannes Achtzehn, Scott Moffat, Nora Hennies, Johannes Fuß, Christian Döller, Thomas Wolbers, Tobias Sommer
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Associations between hair-derived cannabinoid levels, self-reported use, and cannabis-related problems Psychopharmacology (IF 3.4) Pub Date : 2024-02-26
Abstract Rationale As cannabis potency and cannabis use are increasing in newly legalized markets, it is increasingly important to measure and examine the effects of cannabinoid exposure. Objectives The current study aims to assess how hair-derived cannabinoid concentrations – offering insight into three-month cumulative exposure – are associated with common self-report measures of cannabis use and
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CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state Psychopharmacology (IF 3.4) Pub Date : 2024-02-24 Patty T. Huijgens, Roy Heijkoop, Louk J.M.J. Vanderschuren, Heidi M.B. Lesscher, Eelke M.S. Snoeren
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Dorsal hippocampal astrocytes mediate the development of heroin withdrawal-enhanced fear learning Psychopharmacology (IF 3.4) Pub Date : 2024-02-24 Shveta V. Parekh, Lydia O. Adams, Gillian A. Barkell, Jacqueline E. Paniccia, Kathryn J. Reissner, Donald T. Lysle
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A dose-ranging study of the physiological and self-reported effects of repeated, rapid infusion of remifentanil in people with opioid use disorder and physical dependence on fentanyl Psychopharmacology (IF 3.4) Pub Date : 2024-02-22 Joshua A. Lile, Thomas P. Shellenberg, Shanna Babalonis, Kevin W. Hatton, Lon R. Hays, Abner O. Rayapati, William W. Stoops, Michael J. Wesley
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Attenuated incubation of ethanol-induced conditioned taste aversion in a model of dependence Psychopharmacology (IF 3.4) Pub Date : 2024-02-22 Lindsey A. Ramirez, Kathryn R. Przybysz, Joseph R. Pitock, E. Margaret Starr, Hyerim Yang, Elizabeth J. Glover
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Synergistic antidepressant-like effect of citicoline and CB 1 agonist in male mice Psychopharmacology (IF 3.4) Pub Date : 2024-02-21 Aysan Amanzade, Fatemeh Khakpai, Mohammad-Reza Zarrindast
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Withdrawal syndrome after antipsychotics discontinuation: an analysis of the WHO database of spontaneous reports (Vigibase) between 2000 and 2022 Psychopharmacology (IF 3.4) Pub Date : 2024-02-20 Wilhelm Storck, Tanguy Taillefer de Laportalière, Antoine Yrondi, Hervé Javelot, Fabrice Berna, François Montastruc
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The role of the peripheral and central adrenergic system in the construction of the subjective emotional experience of panic Psychopharmacology (IF 3.4) Pub Date : 2024-02-16 Jette H. de Vos, Koen R. J. Schruers, Glen Debard, Bert Bonroy, David E. J. Linden, Nicole K. Leibold
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Effects of arginine vasopressin on human anxiety and associations with sex, dose, and V1a-receptor genotype Psychopharmacology (IF 3.4) Pub Date : 2024-02-15
Abstract Rationale Arginine vasopressin (AVP) has dose- and sex-specific effects on social behavior, and variation in social responses is related to variation in the V1a receptor gene in animals. Whether such complexity also characterizes AVP effects on anxiety in humans, or whether V1a genotype is related to anxiety and/or AVP’s ability to affect it, remains to be determined. Objective To test if
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Distinct roles of the left and right prelimbic cortices in the modulation of ethanol consumption in male mice under acute and chronic social defeat stress Psychopharmacology (IF 3.4) Pub Date : 2024-02-13 Lucas Canto-de-Souza, Daniela Baptista-de-Souza, Ricardo Luiz Nunes-de-Souza, Cleopatra Planeta
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The impact of doxycycline on human contextual fear memory Psychopharmacology (IF 3.4) Pub Date : 2024-02-09 Jelena M. Wehrli, Yanfang Xia, Aslan Abivardi, Birgit Kleim, Dominik R. Bach
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Individual differences in GHB consumption in a new voluntary GHB self-administration model in outbred rats Psychopharmacology (IF 3.4) Pub Date : 2024-02-09
Abstract Background and purpose The use of the recreational drug gamma-hydroxybutyric acid (GHB) has increased over the past decade, concomitantly leading to a higher incidence of GHB use disorder. Evidence-based treatment interventions are hardly available and cognitive effects of long-term GHB use remain elusive. In order to study the development of GUD and the causal effects of chronic GHB consumption
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Relationship between opioid cross-tolerance during buprenorphine stabilization and return to opioid use during buprenorphine dose tapering Psychopharmacology (IF 3.4) Pub Date : 2024-02-08 Mark K. Greenwald, Tolani Sogbesan, Tabitha E.H. Moses
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Intermittent nicotine access is as effective as continuous access in promoting nicotine seeking and taking in rats Psychopharmacology (IF 3.4) Pub Date : 2024-02-07 Hajer E. Algallal, Vincent Jacquemet, Anne-Noël Samaha
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Diosgenin alleviates alcohol-mediated escalation of social defeat stress and the neurobiological sequalae Psychopharmacology (IF 3.4) Pub Date : 2024-02-05 Benneth Ben-Azu, Emuesiri Goodies Moke, Lilian E. Chris-Ozoko, Efe J. Jaiyeoba-Ojigho, Olusegun G. Adebayo, Abayomi Mayowa Ajayi, Mega O. Oyovwi, Gideon Odjugo, Vincent I. Omozojie, Goddey Ejomafuwe, Nzubechukwu Onike, Aya-Ebi O. Eneni, Chukwuyenum P. Ichipi-Ifukor, Ifeakachuku F. Achuba
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Rapamycin attenuates reconsolidation of a backwards-conditioned aversive stimuli in female mice Psychopharmacology (IF 3.4) Pub Date : 2024-02-05 Jared Trask, Phillip E. MacCallum, Haley Rideout, Evan L. Preisser, Jacqueline J. Blundell
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Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence Psychopharmacology (IF 3.4) Pub Date : 2024-02-03 Lucie Vignal, Cassandre Vielle, Maya Williams, Nicolas Maurice, Mickael Degoulet, Christelle Baunez
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Serum indoleamine 2, 3-dioxygenase and tryptophan-2, 3-dioxygenase: potential biomarkers for the diagnosis of major depressive disorder Psychopharmacology (IF 3.4) Pub Date : 2024-01-30
Abstract Objective The objective of this study was to observe the changes in the levels of indoleamine 2, 3-dioxygenase (IDO) and tryptophan-2, 3-dioxygenase (TDO) in patients with major depressive disorder (MDD) and investigate their potential role as novel biomarkers for diagnosing MDD. Methods A total of 55 MDD patients and 55 healthy controls (HC) were enrolled in the study. The severity of MDD
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Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation Psychopharmacology (IF 3.4) Pub Date : 2024-01-30 Kaikai Zhou, Shasha Xu
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Adult consequences of repeated nicotine and Δ9-tetrahydrocannabinol (THC) vapor inhalation in adolescent rats Psychopharmacology (IF 3.4) Pub Date : 2024-01-29 Arnold Gutierrez, Kevin M. Creehan, Yanabel Grant, Michael A. Taffe
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Acute, but not repeated, cocaine exposure alters allopregnanolone levels in the midbrain of male and female rats Psychopharmacology (IF 3.4) Pub Date : 2024-01-29 Minna H. McFarland, Meira M. F. Machado, Griffin M. Sansbury, Kate C. Musselman, Giorgia Boero, Todd K. O’Buckley, Crystal C. Carr, A. Leslie Morrow, Donita L. Robinson
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L-DOPA and oxytocin influence the neural correlates of performance monitoring for self and others Psychopharmacology (IF 3.4) Pub Date : 2024-01-29 Myrthe Jansen, Sandy Overgaauw, Ellen R. A. de Bruijn
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The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism Psychopharmacology (IF 3.4) Pub Date : 2024-01-26 Xin Liu, Yongzeng Jin, Xinyi Cheng, Qinghua Song, Yanan Wang, Ling He, Tong Chen
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An economon model of drug addiction Psychopharmacology (IF 3.4) Pub Date : 2024-01-26
Abstract The term “economon” (i:’ka.nə.muhn; plural: economa) is introduced here to describe an economic unit composed of two participants engaged in mutually reinforcing operant behavior. Economa are basic building blocks of transactional behavior that aggregate in social networks called economies. In a drug-addiction economon, operant behavior by one participant (the “supplier”) provides an addictive
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Activation of NOP receptor increases vulnerability to stress: role of glucocorticoids and CRF signaling Psychopharmacology (IF 3.4) Pub Date : 2024-01-25 Victor A. D. Holanda, Raissa N. de Almeida, Matheus C de Oliveira, Edilson D. da Silva Junior, Nicole L. Galvão-Coelho, Girolamo Calo’, Chiara Ruzza, Elaine C. Gavioli
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Cue-exposure treatment influences resting-state functional connectivity—a randomized controlled fMRI study in alcohol use disorder Psychopharmacology (IF 3.4) Pub Date : 2024-01-23 Àlvar Farré-Colomés, Haoye Tan, Sarah Gerhardt, Martin Fungisai Gerchen, Martina Kirsch, Sabine Hoffmann, Peter Kirsch, Falk Kiefer, Sabine Vollstädt-Klein
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An automated group-housed oral fentanyl self-administration method in mice Psychopharmacology (IF 3.4) Pub Date : 2024-01-22 Noa Peretz-Rivlin, Idit Marsh-Yvgi, Yonatan Fatal, Anna Terem, Hagit Turm, Yavin Shaham, Ami Citri