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Risk factors for inadequate bowel preparation before colonoscopy: A meta‐analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-23 Lina Feng, Jialun Guan, Ruonan Dong, Kai Zhao, Mingyu Zhang, Suhong Xia, Yu Zhang, Liping Chen, Fang Xiao, Jiazhi Liao
ObjectiveThis meta‐analysis aimed to comprehensively explore the risk factors for inadequate bowel preparation (IBP).MethodsWe searched the Embase, PubMed, Web of Science, and The Cochrane Library databases up to August 24, 2023, to identify observational studies and randomized controlled trials (RCTs) that examined risk factors for IBP. A random effects model was used to pool the adjusted odds ratios
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The application of acupuncture‐moxibustion therapy in perioperative period pain control Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-17 Jun Xiong, Yuxin Li, Yingping Kuang, Han Hu, Lijun Yao, Meng Lin
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Effects of initiation time of levothyroxine therapy in women with gestational subclinical hypothyroidism and negative thyroid peroxidase antibodies on the neurological development of offspring Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-15 Jiajia Chen, Zhenyao Li, Fengli Yin, Jiale Bao, Yuanfan Lu, Xiaoting Yu, Xianping Huang, Huiqiu Xiang, Tong Zhou, Jing Zhu, Zhangye Xu
Subclinical hypothyroidism (SCH) is characterized by an elevated thyroid-stimulating hormone (TSH) with normal thyroxine (T4) levels. The 2017 American Thyroid Association (ATA) recommends that an upper reference limit of 4.0 mIU/L should be used in the absence of pregnancy-specific TSH ranges.1 It is well known that overt hypothyroidism exerts a profound effect on pregnancy outcomes; conflicting data
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The detection of circulating tumor cells indicates poor therapeutic efficacy and prognosis in patients with nonsmall cell lung cancer: A systematic review and meta‐analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-11 Shan Wang, Xiaolin Liu, Hongwei Lv, Jing Yu, Huihui Li
ObjectiveThe efficacy and prognostic value of circulating tumor cells (CTCs) in nonsmall cell lung cancer (NSCLC) are controversial based on the existing research. This systematic review and meta‐analysis evaluated the significance of CTCs in NSCLC therapy monitoring and prognosis prediction, supporting their potential as clinical biomarkers.MethodsWe conducted a comprehensive search of PubMed, Embase
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Model‐based meta‐analysis of omalizumab in treating patients with chronic idiopathic/spontaneous urticaria Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-04 Aiping Zhao, Ke Zhang, Zhen Wang, Kaihe Ye, Zhaosi Xu, Xiao Gong, Guanghu Zhu
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Fluids in the treatment of diabetic ketoacidosis in children: A systematic review Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-04 Daniela Patino‐Galarza, Andres Duque‐Lopez, Ginna Cabra‐Bautista, Jose A. Calvache, Ivan D. Florez
AimTo determine the comparative effectiveness of fluid schemes for children with diabetic ketoacidosis (DKA).MethodsWe conducted a systematic review with an attempt to conduct network meta‐analysis (NMA). We searched MEDLINE, EMBASE, CENTRAL, Epistemonikos, Virtual Health Library, and gray literature from inception to July 31, 2022. We included randomized controlled trials (RCTs) in children with DKA
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Step count and multiple health outcomes: An umbrella review Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-03 Zhimin Ao, Hongbo He, Hongxia Shi, Hong Liu
ObjectiveThis study aimed to quantify the association between step count and multiple health outcomes in a healthy population.MethodsPubMed, Embase, Web of Science, and The Cochrane Library were systematically searched for systematic reviews and meta‐analyses from inception to April 1, 2022. Literature screening, data extraction, and data analysis were performed in this umbrella review. The intervention
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Thiazide‐associated hyponatremia in arterial hypertension patients: A nationwide population‐based cohort study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-03 Soie Kwon, Hasung Kim, Jungkuk Lee, Jungho Shin, Su Hyun Kim, Jin Ho Hwang
ObjectiveThiazides are the first‐line treatment for hypertension, however, they have been associated with hospitalizations for thiazide‐associated hyponatremia (TAH). The aim of this study was to evaluate the risk of TAH and other drug‐associated hyponatremia in a Korean population.MethodsThe study used big data from the National Health Insurance Sharing Service of 1,943,345 adults treated for hypertension
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A computable biomedical knowledge system: Toward rapidly building candidate‐directed acyclic graphs Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-04-01 Yongmei Bai, Xuanyu Shi, Jian Du
AimIt is essential for health researchers to have a systematic understanding of third‐party variables that influence both the exposure and outcome under investigation, as shown by a directed acyclic graph (DAG). The traditional construction of DAGs through literature review and expert knowledge often needs to be more systematic and consistent, leading to potential biases. We try to introduce an automatic
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Critical appraisal of a statistical analysis: A novel visual guide Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-27 Lisa Kuramoto, Mike Marin, Jacquelyn J. Cragg
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Polypharmacy and risk of fractures in older adults: A systematic review Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-22 Marie-Eve Gagnon, Denis Talbot, Florence Tremblay, Katherine Desforges, Caroline Sirois
Fractures have serious health consequences in older adults. While some medications are individually associated with increased risk of falls and fractures, it is not clear if this holds true for the use of many medications (polypharmacy). We aimed to identify what is known about the association between polypharmacy and the risk of fractures in adults aged ≥65 and to examine the methods used to study
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Rapid review: A review of methods and recommendations based on current evidence Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-21 Qiong Guo, Guiyu Jiang, Qingwen Zhao, Youlin Long, Kun Feng, Xianlin Gu, Yihan Xu, Zhengchi Li, Jin Huang, Liang Du
Rapid review (RR) could accelerate the traditional systematic review (SR) process by simplifying or omitting steps using various shortcuts. With the increasing popularity of RR, numerous shortcuts had emerged, but there was no consensus on how to choose the most appropriate ones. This study conducted a literature search in PubMed from inception to December 21, 2023, using terms such as “rapid review”
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A data-driven newsvendor model for elective-emergency admission control under uncertain inpatient bed capacity Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-20 Wenwu Shen, Le Luo, Li Luo, Lin Zhang, Ting Zhu
Elective-emergency admission control referred to allocating available inpatient bed capacity between elective and emergency hospitalization demand. Existing approaches for admission control often excluded several complex factors when making decisions, such as uncertain bed capacity and unknown true probability distributions of patient arrivals and departures. We aimed to create a data-driven newsvendor
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An evidence-based guideline on treating lumbar disc herniation with traditional Chinese medicine Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-19 Xiaokuan Qin, Kai Sun, Weiguo Xu, Jinghua Gao, Hong Jiang, Wei Chen, Ling Zhang, Zhenhua Li, Wuyin Li, Puwei Yuan, Kexin Yang, Peijian Tong, Yuanming Zhong, Xiaofeng Zhu, Xiaoming Wan, Chengjian He, Yanguo Wang, Xilin Xu, Yong Huang, Zhihai Zhang, Yifei Huang, Wei Guo, Junling Cao, Tianxiao Feng, Xu Wang, Yuhui Yin, Hao Wang, Chuanrui Sun, Xiangyu Xiao, Xu Wei, Liguo Zhu
Lumbar disc herniation (LDH), as one of the most common causes of lower back pain, imposes a heavy economic burden on patients and society. Conservative management is the first-line choice for the majority of LDH patients. Traditional Chinese medicine (TCM) is an important part of conservative treatment and has attracted more and more international attention.
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Handling time-varying treatments in observational studies: A scoping review and recommendations Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-19 Jiayue Xu, Qiao He, Mingqi Wang, Mei Liu, Qianrui Li, Yan Ren, Minghong Yao, Guowei Li, Kevin Lu, Kang Zou, Wen Wang, Xin Sun
Time-varying treatments are common in observational studies. However, when assessing treatment effects, the methodological framework has not been systematically established for handling time-varying treatments. This study aimed to examine the current methods for dealing with time-varying treatments in observational studies and developed practical recommendations.
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Risk of myocarditis after three doses of COVID-19 mRNA vaccines in the United States, 2020–2022: A self-controlled case series study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-17 Daoyuan Lai, Dickson Lim, Junfeng Lu, Han Wang, Tao Huang, Yan Dora Zhang
Myocarditis is a recognized safety concern following COVID-19 mRNA vaccination. However, there is limited research quantifying the risk associated with the third dose or comparing the risk between the three doses. The US Vaccine Adverse Event Reporting System (VAERS) is a passive surveillance system that monitors rare adverse events after US-licensed vaccination. However, studies analyzing VAERS data
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Osteopathic manipulative treatment for chronic inflammatory diseases Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-15 Ross Gillan, Gabrielle Bachtel, Kassidy Webber, Yasmine Ezzair, Nicole E. Myers, Anupam Bishayee
Chronic inflammatory diseases (CIDs) are debilitating and potentially lethal illnesses that affect a large proportion of the global population. Osteopathic manipulative treatment (OMT) is a manual therapy technique developed and performed by osteopathic physicians that facilitates the body's innate healing processes. Therefore, OMT may prove a beneficial anti-inflammatory modality useful in the management
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The impact of blinding on estimated treatment effects in randomized clinical trials on acupuncture: A meta-epidemiological study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-11 Youlin Long, Na Zhang, Xinyao Wang, Ruixian Tang, Qiong Guo, Jin Huang, Liang Du
To evaluate the sole impact of blinding patients and outcome assessors in acupuncture randomized controlled trials (RCTs) on treatment effects while considering the type of outcome measures.
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Effects of folic acid supplementation on cognitive impairment: A meta-analysis of randomized controlled trials Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-11 Manru Xu, Yue Zhu, Jinxin Chen, Jie Li, Jingbo Qin, Yiran Fan, Pan Ren, Huixue Hu, Wenbin Wu
With the increasing number of patients with cognitive impairment, nonpharmacological ways to delay cognitive impairment have attracted people's attention, such as lifestyle changes and nutritional supplementation. Folic acid supplementation appears to be a promising treatment option. However, it remains controversial whether folic acid supplementation is effective in delaying adult's cognitive impairment
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Time‐varying effects of sodium‐glucose cotransporter‐2 inhibitors in patients with heart failure: An updated meta‐analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-11 Xinyu Zou, Qingyang Shi, Sheyu Li
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Discrepancies in breast cancer guideline recommendations despite similar Cochrane systematic review conclusions Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-03-09 Zhigang Zhang, Jie Cheng, Jialu Hou, Mingming Niu, Ya Gao, Jianguo Xu, Qingyong Zheng, Kexin Ji, Min Zhang, Tian Hao, Ning Li, Xinyi Han, Xiujuan Ma, Jiajia Kong, Rui Wang, Ye Zhao, Jinhui Tian, Xiaofang Hu
This study aims to describe the citation patterns of Cochrane systematic reviews (CSR) in guidelines for managing breast cancer.
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Digital health integration for noncommunicable diseases: Comprehensive process mapping for full-life-cycle management Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-02-15 Tianrui He, Wenbin Cui, Yuxuan Feng, Xingyi Li, Guangjun Yu
To create a systematic digital health process mapping framework for full-life-cycle noncommunicable disease management grounded in key stakeholder engagement.
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Does HPV biotype influence the characteristics and evolution of plantar warts? Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-02-02 Sara García-Oreja, Francisco Javier Álvaro-Afonso, David Sevillano-Fernández, Esther Alicia García-Morales, Mateo López-Moral, José Luis Lázaro-Martínez
Few studies have addressed the relationship of human papillomavirus (HPV) biotypes to patient characteristics and the clinical signs, course, and response to the treatment of plantar warts.
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Consensus for a primary care clinical decision-making tool for assessing, diagnosing, and managing low back pain in Alberta, Canada Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-01-25 Breda H. F. Eubank, Jason Martyn, Geoff M. Schneider, Gord McMorland, Sebastian W. Lackey, Xu Rong Zhao, Mel Slomp, Jason R. Werle, Jill Robert, Kenneth C. Thomas
Low back pain (LBP) is a common condition causing disability and high healthcare costs. Alberta faces challenges with unnecessary referrals to specialists and long wait times. A province-wide standardized clinical care pathway based on evidence-based best practices can improve efficiency, reduce wait times, and enhance patient outcomes. Implementing such pathways has shown success in other areas of
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Topical antimitotic treatments for plantar warts are more beneficial: A Bayesian network meta-analysis of randomized controlled trials Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-01-19 Yantao Xu, Ying Wang, Kai Huang, Weihong Huang, Shuang Zhao, Zixi Jiang
Plantar warts are common infectious cutaneous growths causing severe physiological and psychological discomforts in patients and heaving global financial burdens. However, paucity of clear-cut guidelines for plantar warts, selecting appropriate treatments for plantar warts remains challenging. The objective of the study is to evaluate the efficacy and safety of common treatments for plantar warts.
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Core outcome sets for myocardial infarction in clinical trials of traditional Chinese medicine and Western medicine Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-01-12 Ruijin Qiu, Siqi Wan, Changming Zhong, Songjie Han, Tianmai He, Ya Huang, Xuxu Wei, Meng Li, Zhiyue Guan, Xinyi Zhang, Huanlin Wu, Hongcai Shang
Clinical trials of traditional Chinese medicine (TCM) and Western medicine showed there was heterogeneity of outcome reporting in myocardial infarction (MI). Developing a core outcome set (COS) might improve the consistency of outcome reporting in future clinical trials.
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Diagnostic performance of angiography-derived fractional flow reserve and CT-derived fractional flow reserve: A systematic review and Bayesian network meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2024-01-11 Zhongxiu Chen, Junyan Zhang, Yujia Cai, Hongsen Zhao, Duolao Wang, Chen Li, Yong He
Accumulating evidence has demonstrated that fractional flow reserves (FFRs) derived from invasive coronary angiograms (CA-FFRs) and coronary computed tomography angiography-derived FFRs (CT-FFRs) are promising alternatives to wire-based FFRs. However, it remains unclear which method has better diagnostic performance. This systematic review and meta-analysis aimed to compare the diagnostic performances
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Enhancing generalizability and efficiency in clinical trials through dynamic information borrowing for both experimental and control arms: A simulation study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-26 Jiaying Yang, Guochun Li
Utilizing external information in clinical trials enhances validity by including a wider population and expedites the implementation of adaptive designs, ultimately improving research efficiency. However, current research focused on scenarios in which only the control group benefited from the utilization of external information, while trials involving external information in both experimental and control
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Guidelines of integrated Chinese and western medicine for diagnosis and treatment of chronic obstructive pulmonary disease (2022) Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-21 Jiansheng Li, Rongchang Chen, Xueqing Yu, Huiguo Liu
Chronic obstructive pulmonary disease (COPD), with high prevalence rate, mortality, disability rate, and heavy disease burden, has become a critical chronic disease seriously threatening public health worldwide. Traditional Chinese medicine and Western medicine both have shown advantages in diagnosing and treating COPD, which has been widely applied in the clinics. In order to improve the diagnostic
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Guideline on Establishing Diagnostic Criteria for Chinese Medicine Syndromes Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-21 Jiansheng Li, Yang Xie, Liu Chun, Zhiwan Wang
To formulate the guideline for the development of diagnostic criteria for Chinese medicine syndromes, which can contribute to standardization of development of Chinese medicine syndrome diagnostic standards.
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General anesthesia versus nongeneral anesthesia during endovascular therapy for acute ischemic stroke: A systematic review and meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-21 Xinyan Wang, Youxuan Wu, Fa Liang, Hongqiu Gu, Minyu Jian, Yunzhen Wang, Haiyang Liu, Ruquan Han
This study compares the safety and efficacy of general anesthesia (GA) and nongeneral anesthesia (non-GA) on functional outcomes in patients receiving endovascular therapy for ischemic stroke.
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Treatment response in hemato-oncology in the context of the German early benefit assessment of drugs compared to clinical practice Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-21 Nannette Baltes, Andrea Icks, Charalabos-Markos Dintsios
High payer deficits resulted in a regulation in 2010, which forced new pharmaceuticals in Germany after market access to undergo an early benefit assessment (EBA) based on patient-relevant outcomes to prove an added benefit compared to existing therapies.1, 2 This process had been described in detail elsewhere.3 In hemato-oncology, the heterogeneity of the clinical pictures resulted in a large number
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Reporting, handling, and interpretation of time-varying drug treatments in observational studies using routinely collected healthcare data Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-18 Wen Wang, Qiao He, Jiayue Xu, Mei Liu, Mingqi Wang, Qianrui Li, Xia Zhang, Yunxiang Huang, Yuanjin Zhang, Ling Li, Kang Zou, Guowei Li, Kevin Lu, Pei Gao, Feng Chen, Jeff Jianfei Guo, Min Yang, Xin Sun
Time-varying drug treatments are common in studies using routinely collected health data (RCD) for assessing treatment effects. This study aimed to examine how these studies reported, handled, and interpreted time-varying drug treatments.
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Causal relationship between sleep traits and cognitive impairment: A Mendelian randomization study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-18 Qing Wang, Shihan Xu, Fenglan Liu, Yanfei Liu, Keji Chen, Luqi Huang, Fengqin Xu, Yue Liu
Observational studies had demonstrated a link between sleep disturbances and cognitive decline. Here, we aimed to investigate the causal association between genetically predicted sleep traits and cognitive impairment using Mendelian randomization (MR).
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First-line CDK4/6 inhibitor-based combinations for HR+/HER2– advanced breast cancer: A Bayesian network meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-16 Xianan Guo, Yunxiang Zhou, Kun Zhang, Wei Lu, Xi Zhong, Shijie Wu, Lu Shen, Huihui Chen, Yiding Chen
International guidelines recommend cyclin-dependent kinase 4/6 inhibitor (CDK4/6i)-based first-line therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2−) advanced breast cancer (ABC). However, direct drug comparisons are lacking. We aimed to identify the most effective and safe therapy through network meta-analysis (NMA).
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Efficacy and safety of pharmacological intervention for smoking cessation in smokers with diseases: A systematic review and network meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-16 Xin Xing, Xue Shang, Xinxin Deng, Kangle Guo, E Fenfen, Liying Zhou, Yongsheng Wang, Chaoqun Yang, Kehu Yang, Xiuxia Li
To investigate the most effective and best-tolerated drugs for treating diseased smokers.
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Efficacy of scalp stimulation for multidomain cognitive impairment in patients with post-stroke cognitive impairment and dementia: A network meta-analysis and meta-regression of moderators Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-15 Minjie Xu, Ying Li, Chi Zhang, Yanan Ma, Leyi Zhang, Yuai Yang, Zihan Zhang, Tiantian Meng, Junyi He, Haifang Wang, Shuren Li, Georg S Kranz, Mingjing Zhao, Jingling Chang
Scalp stimulation has gained more traction for post-stroke cognitive impairment and dementia (PSCID); the interaction between stimulation targets and parameters influences the response to the stimulation. However, the most efficacious treatment for improving different domains of cognitive impairment remains unknown.
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Critical evaluation of established risk prediction models for acute respiratory distress syndrome in adult patients: A systematic review and meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-12-06 Tao Wei, Siyi Peng, Xuying Li, Jinhua Li, Mengdan Gu, Xiaoling Li
To assess the performance of validated prediction models for acute respiratory distress syndrome (ARDS) by systematic review and meta-analysis.
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Pathways to care for Long COVID and for long-term conditions from patients' and clinicians' perspective Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-11-30 Fidan Turk, Jennifer Sweetman, Gail Allsopp, Michael Crooks, Dan J Cuthbertson, Mark Gabbay, Lyth Hishmeh, Gregory Y. H. Lip, W. David Strain, Nefyn Williams, Dan Wootton, Amitava Banerjee, Christina van der Feltz-Cornelis
Long COVID (LC) affects approximately 45% of COVID-19 survivors,1 featuring persistent symptoms lasting over 4 weeks without an alternative explanation.2 The recent development of LC services aims to provide structured or integrated care.3 Given the current challenges in the UK healthcare system, we explored access to care for people with LC. We compared this to other long-term conditions (LTCs), concerning
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Machine learning for predicting intraventricular hemorrhage in preterm infants. Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-11-02 Tingting Zhu,Yi Yang,Jun Tang,Tao Xiong
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Risk of bias in epidemiological studies regarding nutrition interventions for COVID-19. Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-10-22 Tianyi He,Xueting Liu,Ruiqi Lv,Guo Cheng
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Scope, design, and reporting of prediction models for antineoplastic drugs-related adverse drug events: A systematic review of machine learning and traditional modeling. Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-10-20 Dan Jiang,Zaiwei Song,Yang Hu,Xinya Li,Rongsheng Zhao
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Use of statins and risk of uterine leiomyoma: A cohort study in the UK Biobank Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-10-17 Xuefeng Jiao, Hailong Li, Linan Zeng, Lu Han, Huazhen Yang, Yao Hu, Yuanyuan Qu, Wenwen Chen, Yajing Sun, Wei Zhang, Donghao Lu, Lingli Zhang
Statins are primarily used to treat hypercholesterolemia and for the secondary prevention of coronary artery disease. Besides their lipid-lowering effect, statins demonstrate other pleiotropic effects. For example, experimental studies of human cell lines and animal models have demonstrated that statins could suppress uterine leiomyoma growth and may prevent uterine leiomyoma.1, 2 However, only two
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Assessment of post-traumatic stress disorder (PTSD) in elderly survivors of the Wenchuan earthquake: A cross-sectional study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-10-05 Yang Peng, Bingqing Lu, Jin Wen
Post-traumatic stress disorder (PTSD) is a prevalent condition characterized by prolonged psychological distress following traumatic events encompassing serious health threats, domestic abuse, and natural disasters. The onset and persistence of PTSD can be attributed to advanced age. This study aimed to explore the occurrence and influencing factors of enduring post-traumatic stress disorder (PTSD)
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Effects of the Informed Health Choices secondary school intervention: A prospective meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-21 Faith Chesire, Michael Mugisha, Ronald Ssenyonga, Christopher J. Rose, Allen Nsangi, Margaret Kaseje, Nelson K. Sewankambo, Matt Oxman, Sarah E. Rosenbaum, Jenny Moberg, Astrid Dahlgren, Simon Lewin, Andrew D. Oxman
The aim of this prospective meta-analysis was to synthesize the results of three cluster-randomized trials of an intervention designed to teach lower-secondary school students (age 14–16) to think critically about health choices.
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Effects of the informed health choices secondary school intervention on the ability of students in Kenya to think critically about health choices: A cluster-randomized trial Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-21 Faith Chesire, Margaret Kaseje, Marlyn Ochieng, Benson Ngatia, Michael Mugisha, Ronald Ssenyonga, Matt Oxman, Allen Nsangi, Daniel Semakula, Christopher James Rose, Laetitia Nyirazinyoye, Astrid Dahlgren, Simon Lewin, Nelson K Sewankambo, Sarah Rosenbaum, Andrew D Oxman
There is an overabundance of claims about the advantages and disadvantages of health interventions. People need to be able to appraise the reliability of these claims. The aim of this two-arm cluster-randomized trial was to evaluate the Informed Health Choices secondary school intervention designed to teach students to assess claims about the effects of health actions and make informed decisions.
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You are not lab rats at teaching hospitals: A systematic review of resident and fellow participation leads to improved colonoscopy Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-21 Chenyu Sun, Yue Chen, Shaodi Ma, Mengqing Liu, Vicky Yau, Na Hyun Kim, Sujatha Kailas, Scott Lowe, Rachel Bentley, Shuya Chen, Jie Liu, Muzi Meng, Yuting Huang, Qin Zhou, Yuyan Wu
Participation in colonoscopies is an essential aspect of endoscopic training. The purpose of this study was to explore the impact of fellow/trainee participation on colonoscopy outcomes.
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Effects of the Informed Health Choices secondary school intervention on the ability of students in Rwanda to think critically about health choices: A cluster-randomized trial Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-21 Michael Mugisha, Laetitia Nyirazinyoye, Clarisse Marie Claudine Simbi, Faith Chesire, Ronald Senyonga, Matt Oxman, Allen Nsangi, Daniel Semakula, Christopher James Rose, Jenny Moberg, Astrid Dahlgren, Margaret Kaseje, Simon Lewin, Nelson K. Sewankambo, Sarah Rosenbaum, Andrew D Oxman
The aim of this trial was to evaluate the effects of the Informed Health Choices intervention on the ability of students in Rwandan to think critically and make Informed Health Choices.
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Methodological quality, risk of bias, and reporting quality: A confusion persists Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-19 Clovis Mariano Faggion
Several types of tools are used by researchers to assess the RoB and methodological quality of studies included in systematic reviews.1 This is the case of the Cochrane approach for randomized controlled trials (RCTs), which is based on domain assessment,2 and the Newcastle-Ottawa Scale (NOS) for assessing the methodological quality of nonrandomized studies in meta-analyses, including case-control
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Use of the informed health choices educational intervention to improve secondary students’ ability to think critically about health interventions in Uganda: A cluster-randomized trial Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-19 Ronald Ssenyonga, Andrew D Oxman, Esther Nakyejwe, Faith Chesire, Michael Mugisha, Allen Nsangi, Daniel Semakula, Matt Oxman, Christopher James Rose, Sarah E Rosenbaum, Jenny Moberg, Margaret Kaseje, Laetitia Nyirazinyoye, Astrid Dahlgren, Simon Lewin, Nelson K Sewankambo
The aim was to evaluate the effect of the Informed Health Choices (IHC) educational intervention on secondary students’ ability to assess health-related claims and make informed choices.
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Exploring patient medication adherence and data mining methods in clinical big data: A contemporary review Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-18 Yixian Xu, Xinkai Zheng, Yuanjie Li, Xinmiao Ye, Hongtao Cheng, Hao Wang, Jun Lyu
Increasingly, patient medication adherence data are being consolidated from claims databases and electronic health records (EHRs). Such databases offer an indirect avenue to gauge medication adherence in our data-rich healthcare milieu. The surge in data accessibility, coupled with the pressing need for its conversion to actionable insights, has spotlighted data mining, with machine learning (ML) emerging
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Artificial intelligence and digital health in improving primary health care service delivery in LMICs: A systematic review Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-10 KM Saif-Ur-Rahman, Md Shariful Islam, Joan Alaboson, Oluwadara Ola, Imran Hasan, Nazmul Islam, Shristi Mainali, Tina Martina, Eva Silenga, Mubita Muyangana, Taufique Joarder
Technology including artificial intelligence (AI) may play a key role to strengthen primary health care services in resource-poor settings. This systematic review aims to explore the evidence on the use of AI and digital health in improving primary health care service delivery.
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Cochrane review abstracts are getting longer, but this has no large impact on the reporting quality Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-06 Jasmin Helbach, Kathrin Wandscher, Dawid Pieper, Falk Hoffmann
To evaluate the reporting of abstracts of Cochrane Reviews according to PRISMA-A and to investigate a possible association with the abstract´s length.
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Guidelines for high-flow nasal cannula oxygen therapy in neonates (2022) Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-09-06 Yi Huang, Jing Zhao, Xintian Hua, Keren Luo, Yuan Shi, Zhenlang Lin, Jun Tang, Zhichun Feng, Dezhi Mu
High-flow nasal cannula (HFNC) oxygen therapy, which is important in noninvasive respiratory support, is increasingly being used in critically ill neonates with respiratory failure because it is comfortable, easy to setup, and has a low incidence of nasal trauma. The advantages, indications, and risks of HFNC have been the focus of research in recent years, resulting in the development of the application
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Surgical site infection following open lobectomy in patients with lung cancer: A prospective study Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-07-03 Shiyu Li, Ji Lin, Lijuan Ye, Fu Qiao, Wenzhi Huang, Yalan Peng, Jin Huang
To assess the incidence and risk factors of surgical site infection after open pulmonary lobectomy and to quantify their clinical and economic burden.
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Result reporting and early discontinuation of sepsis trials registered on ClinicalTrials.gov Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-07-02 Handan Hu, Xinyi Wang, Peng Huang
Sepsis is a leading cause of death from infectious disease or traumatic injury. The prevalence and predictor of results underreporting and early stop of sepsis clinical trials remain poorly studied. To fill the gap, we designed this study to characterize sepsis clinical trials registered on ClinicalTrials.gov, particularly to recognize features related to premature discontinuation and lack of results
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Pericardial fat and cardiovascular diseases: A systematic review and meta-analysis Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-06-18 Hanna K. Al-Makhamreh, Ahmad A. Toubasi, Layla M. Al-Harasis, Farah H. Albustanji, Thuraya N. Al-Sayegh, Sarah M. Al-Harasis
Previous studies investigated the effect of pericardial fat on cardiovascular diseases. However, until now there was no systematic review and meta-analysis investigated this association, thus we conducted this article to assess the relationship between pericardial fat and cardiovascular diseases.
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Systematic reviews were the perceived most important source of information for updating a potentially inappropriate medication list for the elderly: An online survey Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-06-14 Dawid Pieper, Nina-Kristin Mann, Mahmoud Moussa, Tim Mathes, Andreas Sönnichsen, Petra Thürmann
Polypharmacy in the elderly is a recognized public health problem. For many diseases several drugs are available. Thus, it is important to rule out drugs with an unfavorable risk-benefit profile in older patients, and to suggest safer alternatives. This is often done by developing and publishing lists of potentially inappropriate medications (PIM). Making evidence-based decisions for the elderly is
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Comparative analysis of systemic oncological treatments and best supportive care for advanced gastresophageal cancer: A comprehensive scoping review and evidence map Journal of Evidence-Based Medicine (IF 7.3) Pub Date : 2023-06-12 Santero Marilina, Meade Adriana, Selva Anna, Acosta-Dighero Roberto, Meza Nicolás, Quintana Maria Jesús, Bracchiglione Javier, Requeijo Carolina, Salazar Josefina, Rodríguez Grijalva Gerardo, Solà Ivan, Urrútia Gerard, Bonfill Cosp Xavier
To identify, describe, and organize the available evidence regarding systemic oncological treatments compared to best supportive care (BSC) for advanced gastresophageal cancer.