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Suicide within five years of hospital-treated self-harm: A data linkage cohort study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-22 Angela Clapperton, Matthew J. Spittal, Jeremy Dwyer, Angela Nicholas, Jane Pirkis
Hospital-treated self-harm is a strong predictor of suicide and hospital contacts may include missed opportunities for suicide prevention. We conducted a data linkage study to identify factors associated with suicide in people treated in hospital for self-harm in Victoria, Australia. We undertook a cohort study following 14,307 people treated in hospital for an episode of self-harm (i.e., either admitted
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Intravenous (IV) ketamine versus intranasal esketamine for depression– Advantage IV ketamine? J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-22 Balwinder Singh, Simon Kung, Jennifer L. Vande Voort
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Frontal Theta Asymmetry may be a new target for reducing the severity of depression and improving cognitive function in depressed patients J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-22 Nannan Pan, Ziyan Fang, Jinwei Wang, Penghui Cao
The prevalence of depressive disorder is increasing due to a variety of factors, which brings a huge strain on individuals, families and society. This study aims to investigate whether there is Frontal Theta Asymmetry (FTA) in depressed patients, and whether FTAs are related to depression severity and cognitive function changes in depressed patients. Participants who met the inclusion criteria were
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Association of reproductive lifespan and age at menopause with depression: Data from NHANES 2005–2018 J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-22 Qian Wu, Yuxin Yan, Rui La, Xing Zhang, Lingchen Lu, Rui Xie, Yulun Xue, Chuan Lin, Wu Xu, Jiangnan Xu, Lixin Huang
The association between reproductive lifespan and depression in older women is unclear. We conducted this analysis to explore whether a shorter reproductive lifespan is associated with higher odds of depression, while also considering the age at menarche and age at menopause. This observational study used data from the National Health and Nutrition Examination Survey (NHANES), which was conducted between
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Pramipexole improves depression-like behavior in diabetes mellitus with depression rats by inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing impaired neuroplasticity J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-22 Ping Li, Tingting Wang, Haipeng Guo, Yingxi Liu, Hongqing Zhao, Tingting Ren, Yingjuan Tang, Yuhong Wang, Manshu Zou
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Risk factors of suicide re-attempt: A two-year prospective study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-22 B. Nobile, I. Jaussent, J.P. Kahn, M. Leboyer, N. Risch, E. Olié, Ph. Courtet
History of suicide attempt (SA) is the strongest predictor of a new SA and suicide. It is primordial to identify additional risk factors of suicide re-attempt. The aim of this study was to identify risk factors of suicide re-attempt in patients with recent SA followed for 2 years. In this multicentric cohort of adult inpatients, the median of the index SA before inclusion was 10 days. Clinicians assessed
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Coping with test anxiety using imagery rescripting: A two-session randomized controlled trial J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-20 Julia Kroener, Anna Maier, Alexander Berger, Zrinka Sosic-Vasic
Up to 55 % of students experience test anxiety (TA), which is characterized by intense physiological and psychological symptoms before or during exams, such as anxiety, fear of failure, sweating, or increased heart rate. Furthermore, TA increases graduation times and can result in discontinuance of the graduate program all together. Previous research demonstrated the beneficial effects of combining
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Safety plan use and suicide-related coping in a sample of Australian online help-seekers J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-19 Christopher Rainbow, Ruth Tatnell, Grant Blashki, Glenn A. Melvin
Suicide safety plans can improve suicide-related coping skills and reduce suicidal thoughts and behaviours (STBs). However, little is known about their use and impact outside of treatment settings, where most suicidal crises will occur. The current study explored the prevalence of safety plan use among an online sample of help-seekers with lifetime STBs, and whether STBs and suicide-related coping
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Effectiveness of structured group psychoeducation for people with bipolar disorder in Rwanda: A randomized open-label superiority trial J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-18 Caroline J. Arnbjerg, Emmanuel Musoni-Rwililiza, Nelly Umulisa Rurangwa, Maja Grønlund Bendtsen, Chantal Murekatete, Darius Gishoma, Jessica Carlsson, Per Kallestrup
Psychoeducation is a cornerstone as an add-on to pharmacotherapy in standard care for individuals with bipolar disorder. However, evidence of the effectiveness of psychoeducation in low-resource settings is scarce. We aimed to assess the effectiveness of structured group psychoeducation versus waiting list on relapse prevention for individuals with bipolar disorder in Rwanda, a low-income country.
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Development and validation of a nomogram prediction model for ADHD in children based on individual, family, and social factors J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-18 Ting Gao, Lan Yang, Jiayu Zhou, Yu Zhang, Laishuan Wang, Yan Wang, Tianwei Wang
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Schizophrenia polygenic risk scores, clinical variables and genetic pathways as predictors of phenotypic traits of bipolar I disorder J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-18 Maria Grigoroiu-Serbanescu, Tracey van der Veen, Tim Bigdeli, Stefan Herms, Carmen C. Diaconu, Ana Iulia Neagu, Nicholas Bass, Johan Thygesen, Andreas J. Forstner, Markus M. Nöthen, Andrew McQuillin
We investigated the predictive value of polygenic risk scores (PRS) derived from the schizophrenia GWAS (Trubetskoy et al., 2022) for phenotypic traits of bipolar disorder type-I (BP-I) in 1878 BP-I cases and 2751 controls from Romania and UK. We used PRSice-v2.3.3 and PRS-CS for computing SCZ3-PRS for testing the predictive power of SCZ3-PRS alone and in combination with clinical variables for several
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Brain stimulation over the left DLPFC enhances motivation for effortful rewards in patients with major depressive disorder J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-18 Rong Bi, Yanli Zhao, Sijin Li, Feng Xu, Weiwei Peng, Shuping Tan, Dandan Zhang
Amotivation is a typical feature in major depressive disorder (MDD), which produces reduced willingness to exert effort. The dorsolateral prefrontal cortex (DLPFC) is a crucial structure in goal-directed actions and therefore is a potential target in modulating effortful motivation. However, it remains unclear whether the intervention is effective for patients with MDD. We employed transcranial magnetic
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Association between overactive bladder and depression in American adults: A cross-sectional study from NHANES 2005–2018 J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-18 Yuyang Zhang, Xu Wu, Guodong Liu, Xingliang Feng, Hui Jiang, Xiansheng Zhang
Overactive bladder (OAB) and depression are both common disorders and there is research suggesting an association between the two, but there is a lack of studies with large samples. The aim of this study is to investigate the association between OAB and depressive symptoms. We used data from the National Health and Nutrition Examination Survey (NHANES) database for the period 2005 to 2018. OAB was
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Health care professional barriers and facilitators to discontinuing antidepressant use: A systematic review and thematic synthesis J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-17 Ellen Van Leeuwen, Emma Maund, Catherine Woods, Hannah Bowers, Thierry Christiaens, Tony Kendrick
Long-term antidepressant (AD) use, much longer than recommended, is very common and can lead to potential harms. To investigate the existing literature on perspectives of health professionals (HPs) regarding long-term AD treatment, focusing on barriers and facilitators to discontinuation. A systematic review with thematic synthesis. Eight electronic databases were searched until August 2023 including
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Hippocampus, amygdala, and insula activation in response to romantic relationship dissolution stimuli: A case-case-control fMRI study on emerging adult students J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-16 A.S.J. Van der Watt, S. Du Plessis, F. Ahmed, A. Roos, E. Lesch, S. Seedat
Romantic relationship dissolutions (RRDs) are associated with posttraumatic stress symptoms (PTSS). Functional magnetic resonance imaging in RRD studies indicate overlapping neural activation similar to posttraumatic stress disorder. These studies combine real and hypothetical rejection, and lack contextual information and control and/or comparison groups exposed to non-RRD or DSM-5 defined traumatic
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Frailty and psychiatric disorders: A bidirectional Mendelian randomization study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-16 Jie-Hai Chen, Hang Lei, Yu-Fei Wan, Xiao-Chun Zhu, Li-Ying Zeng, Hao-Xuan Tang, Yun-Feng Zhao, Ying Pan, Yong-Qiang Deng, Ke-Xuan Liu
The association between frailty and psychiatric disorders has been reported in observational studies. However, it is unclear whether frailty facilitates the appearance of psychiatric disorders or vice versa. Therefore, we conducted a bidirectional Mendelian randomization (MR) study to evaluate the causality. Independent genetic variants associated with frailty index (FI) and psychiatric disorders were
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The therapeutic effectiveness of artificial intelligence-based chatbots in alleviation of depressive and anxiety symptoms in short-course treatments: A systematic review and meta-analysis J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-15 Wenjun Zhong, Jianghua Luo, Hong Zhang
The emergence of artificial intelligence-based chatbot has revolutionized the field of clinical psychology and psychotherapy, granting individuals unprecedented access to professional assistance, overcoming time constraints and geographical limitations with cost-effective convenience. However, despite its potential, there has been a noticeable gap in the literature regarding their effectiveness in
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Factors associated with high and low mental well-being in Spanish university students J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-15 Guillem Navarra-Ventura, Pau Riera-Serra, Miquel Roca, Margalida Gili, Mauro García-Toro, Gemma Vilagut, Itxaso Alayo, Laura Ballester, Maria Jesús Blasco, Pere Castellví, Joan Colom, Cristina Casajuana, Andrea Gabilondo, Carolina Lagares, José Almenara, Andrea Miranda-Mendizabal, Philippe Mortier, José Antonio Piqueras, Victoria Soto-Sanz, Jordi Alonso, UNIVERSAL study group
Previous studies conducted in various nationally representative samples of the general population show that positive mental health is related to social prosperity. However, specific studies in university populations are scarce. In this study, we set out to explore factors associated with mental well-being (MWB) in a representative sample of first-year university students in Spain. MWB was assessed
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Causal association of depression, anxiety, cognitive performance, the brain cortical structure with pulmonary arterial hypertension: A Mendelian randomization study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-15 Zeying Zhang, Shelby Kutty, Wei Peng, Gaoming Zeng, Haiyan Luo, Zhenghui Xiao, Qiming Liu, Yunbin Xiao
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Functional significance of posttraumatic growth in U.S. military veterans J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-15 Tricia Gower, Ian C. Fischer, Jack Tsai, Hun Kang, Peter J. Na, Richard G. Tedeschi, Robert H. Pietrzak
Although many studies indicate that individuals who have experienced a traumatic event can experience posttraumatic growth (PTG), some researchers have questioned the significance of PTG in associations with functioning. The role of PTG in functioning following trauma may be better elucidated by accounting for its joint effects with posttraumatic stress disorder (PTSD) symptoms. Data were analyzed
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BI-REAL: A 12-session DBT skills group intervention adapted for bipolar disorder – A feasibility randomised pilot trial J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-13 Julieta Azevedo, Michaela Swales, Diogo Carreiras, Raquel Guiomar, António Macedo, Paula Castilho
International guidelines endorse psychological treatment for Bipolar Disorder (BD); however, the absence of a recognised gold-standard intervention requires further research. A Dialectical Behaviour Therapy (DBT) skills group intervention with 12 sessions was developed. This pilot randomised controlled trial (RCT) aims to evaluate the feasibility, acceptability, and outcomes variance of Bi-REAL – Respond
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AI algorithm combined with RNA editing-based blood biomarkers to discriminate bipolar from major depressive disorders in an external validation multicentric cohort J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-13 Nicolas Salvetat, Francisco Jesus Checa-Robles, Aurélie Delacrétaz, Christopher Cayzac, Benjamin Dubuc, Diana Vetter, Jacques Dainat, Jean-Philippe Lang, Franziska Gamma, Dinah Weissmann
Bipolar disorder (BD) is a leading cause of disability worldwide, as it can lead to cognitive and functional impairment and premature mortality. The first episode of BD is usually a depressive episode and is often misdiagnosed as major depressive disorder (MDD). Growing evidence indicates that peripheral immune activation and inflammation are involved in the pathophysiology of BD and MDD. Recently
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Adequate methodological reporting and sensitivity analyses are essential to allow reproducibility and interpretability in NLP studies J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-12 Matthew M. Nour
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The moderating role of belongingness in the contribution of depression to suicide ideation following the October 7, 2023, terrorist attack in Israel: A nationwide prospective study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-12 Yossi Levi-Belz, Yael Shoval-Zuckerman, Carmel Blank, Yoav Groweiss, Yuval Neria
With >1300 civilians murdered, the terrorist attack of October 7 is one of the deadliest terrorist attacks in modern history. Previous research documented a sharp increase in depression in the aftermath of the attacks and the military conflict that followed. In this national prospective cohort study, we examined to what extent perceived belongingness (PB) moderates the association between depression
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Reduced myelin content in bipolar disorder: A study of inhomogeneous magnetization transfer J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-12 Zhifeng Zhou, Ziyun Xu, Wentao Lai, Xiaoqiao Chen, Lin Zeng, Long Qian, Xia Liu, Wentao Jiang, Yingli Zhang, Gangqiang Hou
Previous neuroimaging and pathological studies have found myelin-related abnormalities in bipolar disorder (BD), which prompted the use of magnetic resonance (MR) imaging technology sensitive to neuropathological changes to explore its neuropathological basis. We holistically investigated alterations in myelin within BD patients by inhomogeneous magnetization transfer (ihMT), which is sensitive and
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Inter-relationships of depression and insomnia symptoms with life satisfaction in stroke and stroke-free older adults: Findings from the Health and Retirement Study based on network analysis and propensity score matching J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-11 Pan Chen, He-Li Sun, Ling Zhang, Yuan Feng, Sha Sha, Zhaohui Su, Teris Cheung, Katrine K. Wong, Gabor S. Ungvari, Todd Jackson, Qinge Zhang, Yu-Tao Xiang
Depression and insomnia are common co-occurring psychiatric problems among older adults who have had strokes. Nevertheless, symptom-level relationships between these disorders remain unclear. In this study, we compared inter-relationships of depression and insomnia symptoms with life satisfaction among older stroke patients and stroke-free peers in the United States. The study included 1026 older adults
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The relationship between depression and relative fat mass (RFM): A population-based study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-11 Xianlin Zhu, Ya Yue, Lin Li, Liying Zhu, Yuexi Cai, Yanping Shu
Relative fat mass (RFM) is a novel indicator for measuring body fat. The relationship between RFM and depression was explored using National Health and Nutrition Examination Survey (NHANES) data from 2005 to 2018. A general statistical description of the population included in the study was performed, and logistic analyses were used to explore the association between body mass index (BMI), waist circumference
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Exosomal miR-1202 mediates Brodmann Area 44 functional connectivity changes in medication-free patients with major depressive disorder: An fMRI study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Shuguang Han, Qingtong Zheng, Zixuan Zheng, Jie Su, Xiaohua Liu, Changzhou Shi, Bo Li, Xuanxuan Zhang, Minghao Zhang, Qian Yu, Ziwei Hou, Ting Li, Bin Zhang, Yong Lin, Ge Wen, Yanjia Deng, Kai Liu, Kai Xu
Previous large-sample postmortem study revealed that the expression of miR-1202 in brain tissues from Brodmann area 44 (BA44) was dysregulated in patients with major depressive disorder (MDDs). However, the specific neuropathological mechanism of miR-1202 as well as its interplay with BA44 circuits in the depressed brain are still unclear. Here, we performed a case-control study with imaging-genetic
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The network structures of depressive and insomnia symptoms among cancer patients using propensity score matching: Findings from the Health and Retirement Study (HRS) J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Meng-Yi Chen, Wei Bai, Xiao-Dan Wu, Sha Sha, Zhaohui Su, Teris Cheung, Ying Pang, Chee H. Ng, Qinge Zhang, Yu-Tao Xiang
Both depression and insomnia are found to be more prevalent in cancer patients compared to the general population. This study compared the network structures of depression and insomnia among cancer patients versus cancer-free participants (controls hereafter). The 8-item Center for Epidemiological Studies Depression Scale (CESD-8) and the 4-item Jenkins Sleep Scale (JSS-4) were used to measure depressive
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The association between intolerance of uncertainty and depressive symptoms during COVID-19 in New York, USA J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Mojdeh Rafieian, Norbert Skokauskas, Keely Cheslack-Postava, Christina W. Hoven
Coronavirus Disease 2019 (COVID-19), a highly contagious respiratory illnesses, has globally impacted mental health. This study aims to investigate the association between intolerance of uncertainty and depressive symptoms during the pandemic in New York, USA, considering COVID-19-related worries as modifiers and mediators. 1227 participants from three ongoing cohort studies, originally centered on
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Association between atherogenic index of plasma and depressive symptoms in US adults: Results from the National Health and Nutrition Examination Survey 2005 to 2018 J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Zhiqiang Ye, Wenjie Huang, Jianing Li, Yuxin Tang, Keyi Shao, Ying Xiong
This study, utilizing data from the U.S. National Health and Nutrition Examination Survey (NHANES) between 2005 and 2018, investigates the association between the atherogenic index of plasma (AIP), a lipid biomarker, and symptoms of depression in American adults. In this cross-sectional study of 12,534 adults aged 20 years and older, depressive symptoms were measured utilizing the Patient Health Questionnaire-9
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Prenatal maternal negative life events associated with child emotional and behavioral problems in the French EDEN cohort J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Sara Avendano, Simi Moirangthem, Muriel Taflet, Barbara Heude, Muriel Koehl, Judith van der Waerden, Naomi Downes
Prenatal negative life events (NLEs) have been linked to adverse health outcomes in children. However, few studies examine this relationship during late childhood using trajectory analyses. Additionally, the impact of specific NLEs domains on child development remains unclear. This study aims to longitudinally explore the association between NLEs (cumulative score and specific NLEs domains) and child
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The effects of health risk behaviors to excess mortality in the population with depression: A cohort study based on NHANES data J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Yanjie Qi, Fanchao Meng, Xiuping Yan, Huanhuan Huang, Xu Chen, Fan He
The population with depression had a considerable excess mortality risk. This increased mortality may be attributed to the biological consequences of depression or the substantial prevalence of health risk behaviors (HRBs). This study aimed to quantify the combined effects of four major HRBs - smoking, excessive alcohol use, physical inactivity, and an unhealthy diet - on excess mortality among depressed
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Understanding heterogeneity, comorbidity, and variability in depression: Idiographic models and depression outcomes J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Claire E. Cusack, Christina Ralph-Nearman, Caroline Christian, Aaron J. Fisher, Cheri A. Levinson
This study uses time-intensive, item-level assessment to examine individual depressive and co-occurring symptom dynamics. Participants experiencing moderate-severe depression ( = 31) completed ecological momentary assessment (EMA) four times per day for 20 days (total observations = 2480). We estimated idiographic networks using MDD, anxiety, and ED items. ED items were most frequently included in
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Network analysis for inter-relationships of the suboptimal health status with depression and anxiety during the COVID-19 pandemic: A perspective of predictive, preventive, and personalized health J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Xue Wang, Yibo Wu, Yu Chen, Qian Gao, Wenting Liu, Jiayi Xu, Shuang Zang
The Coronavirus Disease-2019 (COVID-19) pandemic has had a profound impact on suboptimal health status, depression, and anxiety, necessitating a comprehensive understanding of their inter-relationships at the national level. This study aims to investigate the inter-relationships among suboptimal health status, depression, and anxiety using a network analysis approach. We conducted a national survey
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Identification of novel endoplasmic reticulum-related genes and their association with immune cell infiltration in major depressive disorder J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Lijia Chang, Tong Wang, Youge Qu, Xinrong Fan, Xiangyu Zhou, Yan Wei, Kenji Hashimoto
Several lines of evidence point to an interaction between genetic predisposition and environmental factors in the onset of major depressive disorder (MDD). This study is aimed to investigate the pathogenesis of MDD by identifying key biomarkers, associated immune infiltration using bioinformatic analysis and human postmortem sample. The Gene Expression Omnibus (GEO) database of GSE98793 was adopted
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Osteoporosis and depression in perimenopausal women: From clinical association to genetic causality J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-10 Xiangyun Guo, Yun She, Qingqing Liu, Jinran Qin, Liang Wang, Aili Xu, Baoyu Qi, Chuanrui Sun, Yanming Xie, Yong Ma, Liguo Zhu, Weiwei Tao, Xu Wei, Yili Zhang
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Impact of leisure physical activity and resistance exercise on the prevalence of depressive symptoms in Korean adults: Analysis of the Korean National Health and Nutrition Examination Survey J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-08 Eun Chan Kim, Ansuk Jeong, Dong Hoon Lee, Dong-Hyuk Park, Justin Y. Jeon
Various physical activity (PA) guidelines recommend leisure PA and resistance exercise (RE). However, the impact of PA and RE on the prevalence of depressive symptoms remains unclear. We investigated whether meeting PA and RE guidelines is associated with the prevalence of depressive symptoms using nationally representative samples. We analyzed data from 11,829 (5111 male and 6718 female) participants
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Self-administered generational surveys combine with genetic analysis to reveal foundations of depression in Japanese adults J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-08 Ryo Takano, Yushin Tominaga, Dong-Jing Fu, John A. Moyer, Yang Cheng, Kinya Okada
Major depressive disorder is a prevalent psychiatric illness characterized by mood disturbances and influenced by various environmental and genetic factors, yet its etiology remains largely unknown. We profiled a self-reported depressive population in Japan with a focus on sociodemographic background, lifestyle, comorbidities, and genetic background, using data from two cohorts, a population-based
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Mood and physiological effects of visual stimulation with images of the natural environment in individuals with depressive and anxiety disorders J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-07 Tomohiro Mizumoto, Harumi Ikei, Kosuke Hagiwara, Toshio Matsubara, Fumihiro Higuchi, Masaaki Kobayashi, Takahiro Yamashina, Jun Sasaki, Norihiro Yamada, Naoko Higuchi, Kenichi Haraga, Fumiaki Kirihara, Emi Okabe, Kumi Asai, Masako Hirotsu, Chong Chen, Yoshifumi Miyazaki, Shin Nakagawa
Nature therapies are gaining attention as non-pharmacological treatments for depressive and anxiety disorders, but research on their effectiveness in patients is limited. This study investigates the mood-improving effects of visual stimulation with natural environmental images in patients with depressive and anxiety disorders. We conducted a randomized crossover comparison trial involving 60 right-handed
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Treatment resistant late-life depression: A narrative review of psychosocial risk factors, non-pharmacological interventions, and the role of clinical phenotyping J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-07 Regan E. Patrick, Rebecca A. Dickinson, Melanie T. Gentry, Joseph U. Kim, Lauren E. Oberlin, Soohyun Park, Jessica L. Principe, Antonio L. Teixeira, Sara L. Weisenbach
Treatment resistant depression (TRD) is a subset of major depressive disorder (MDD) in which symptoms do not respond to front line therapies. In older adults, the assessment and treatment of TRD is complicated by psychosocial risk factors unique to this population, as well as a relative paucity of research. Narrative review aimed at (1) defining TRLLD for clinical practice and research; (2) describing
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The role of loneliness in the association between sexual orientation and depressive symptoms among older adults: A prospective cohort study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-07 Talen Wright, Francesca Solmi, Olesya Ajnakina, Elizabeth Ingram, Aaron Kandola, Stephen Lee, Eleonora Iob, Andrew Steptoe, Ben Thomas, Gemma Lewis
This study aims to understand the mechanisms contributing to the elevated risk of depression among sexual minority older adults compared to heterosexuals. Specifically, the role of loneliness as a potential mediator is investigated to inform targeted interventions for preventing depression in sexual minority populations. Data from the English Longitudinal Study of Ageing, focusing on adults aged over
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Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-07 Hua Xue, Jiajia Chen, Wenhui Fan
Observational studies suggested that immune system disorder is associated with depression. However, the causal association has not been fully elucidated. Thus, we aim to assess the causality of the associations of immune cell profiles with risk of depression through Mendelian randomization analysis. We extracted genetic variances of immune cell traits from a large publicly available genome-wide association
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Overall diet quality, food groups and mental health disorders among Brazilians older than 15 years old: Brazilian National Health Survey – 2019 J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Ana Carolina Barco Leme, Lara Cristiane Natacci, Elizabeth Aparecida Ferraz da Silva Torres
Adherence to a nutrient-dense diet can have an impact on depression and other mental health issues. Little is known whether this is attributed to some or all components and how these differ in a country that is known to have a vast diversity of nutrient-dense foods. The aim was to examine whether there is a relationship between individual food groups with depression and other mental health disorders
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Waning waves of mood: The declining trend of hospitalized patients with affective disorders in Germany J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Nike Walter, Markus Rupp, Adolfo Lambert-Delgado, Alberto Erconvaldo Cobián Mena, Thilo Hinterberger, Thomas Loew
Affective disorders profoundly affect individuals' emotional well-being and quality of life. This study investigates the epidemiology of affective disorders in Germany from 2011 to 2021, focusing on incidence rates, age- and sex-standardized rates, and developmental trends. Using nationwide data of ICD-10 diagnosis codes from 2011 to 2021, this cross-sectional study analyzed inpatient cases of affective
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Lower levels of TRAF1 in Brodmann's area 24, but not 46, in bipolar disorders are not detectable in major depressive disorders J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Brian Dean, Natasha Seymour, Andrew Gibbons
Multiple lines of research implicate inflammation-related pathways in the molecular pathology of mood disorders, with our data suggesting a critical role for aberrant cortical tumour necrosis factor α (TNF)-signaling in the molecular pathology of bipolar disorders (BPD) and major depressive disorders (MDD). To extend our understanding of changes in TNF-signaling pathways in mood disorders we used Western
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The impact of family socioeconomic status on depression in Chinese adolescents: A comparison of life course models J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Jing Zeng, Yuebin Xu
Low socioeconomic status (SES) is a well-recognized risk factor for depression. However, the relationship between the timing of exposure to disadvantaged SES in childhood and depression in adolescence remains to be explored. We examined the differential influence of SES in early childhood, late childhood and adolescence on adolescent depression by modeling life course models. We used longitudinal data
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Characteristics of oxyhemoglobin during the verbal fluency task in subthreshold depression: A multi-channel near-infrared spectroscopy study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Hui Da, Nian Xiang, Min Qiu, Sadia Abbas, Qiang Xiao, Yan Zhang
Subthreshold depression is an essential precursor and risk factor for major depressive disorder, and its accurate identification and timely intervention are important for reducing the prevalence of major depressive disorder. Therefore, we used functional near-infrared spectroscopic imaging (fNIRS) to explore the characteristics of the brain neural activity of college students with subthreshold depression
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Assisted reproductive technologies and postpartum depressive symptoms: A meta-analysis J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Si Si, Ge Zhao, Guang Song, Jing Liu
Assisted reproductive technologies (ARTs) have become the main treatment for infertility. ART treatment can be a stressful life event for infertile females. Whether there is an association between ARTs and postpartum depressive symptoms (PDS) has not been established. PubMed, MEDLINE, EMBASE, PsycINFO, and CNKI were searched. The pooled outcome was the difference in incidence of PDS within 1 year postpartum
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The association between urbanization and depression in the elderly: A network analysis from the complexity science perspective J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Rui Wang, Haoyuan Su, Tao Xu, Wenhui Jiang, Huan Liu, Wei Wang, Ce Chen, Xiancang Ma, Yunchun Chen, Wei Wang
The global increase in urbanization has coincided with a rise in depression prevalence. However, the effect of urbanization on depression remains controversial, especially for the elderly. To clarify how urbanization impacts depression in the elderly from a network perspective. This sectional cohort study used data from China Health and Retirement Longitudinal Study (CHARLS). The occurrence of depressive
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Depression, anxiety, and insomnia symptoms among Chinese college students: A network analysis across pandemic stages J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Jiahong Li, Cong Luo, Lili Liu, Andi Huang, Zijie Ma, Yujing Chen, Yishuai Deng, Jingbo Zhao
As the stages of the COVID-19 pandemic evolved, the symptoms of depression, anxiety, and insomnia have increasingly manifested among Chinese college students. The aim of this study is to investigate the relationships between these symptoms through network analysis among Chinese college students during COVID-19. A three-wave cross-sectional survey was conducted at 22 colleges in Guangdong Province,
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Depressive symptoms and neuroticism mediate the association between traumatic events and suicidality - A latent class mediation analysis of UK Biobank Database J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-06 Doo Woong Lee, Kwanghyun Kim, Jinhee Hyun, Sun Jae Jung
Mental disorders that follow traumatic experience may increase risk of suicidality, but a comprehensive approach to understand how these mental disorders mediate the association between psychological traumatic experience and suicidality should be elucidated. In this study, we attempted to provide comprehensive evidence on how depressive symptoms and neuroticism can mediate the association between psychological
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Digital biomarkers in depression: A systematic review and call for standardization and harmonization of feature engineering J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-05 Carolin Zierer, Corinna Behrendt, Anja Christina Lepach-Engelhardt
General physicians misclassify depression in more than half of the cases. Researchers have explored the feasibility of leveraging passively collected data points, also called digital biomarkers, to provide more granular understanding of depression phenotypes as well as a more objective assessment of disease. This paper provides a systematic review following the PRISMA guidelines (Page et al., 2021)
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Greater within- and between-day instability is associated with worse anxiety and depression symptoms J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-05 Adile Nexha, Luísa K. Pilz, Melissa A.B. Oliveira, Nicoli B. Xavier, Rogério Boff Borges, Benicio N. Frey, Maria Paz L. Hidalgo
Depression and anxiety affect hundreds of millions of people worldwide, and their prevalence increased during the COVID-19 pandemic as social schedules were disrupted. This study explores the associations between anxiety and depression and within- and between-day instability of affective, somatic, and cognitive symptoms during the early pandemic stages. Participants ( = 153, ages 18–77, 72 % female)
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Patterns of comorbid PTSD, depression, alcohol use disorder, and insomnia symptoms in firefighters: A latent profile analysis J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-05 Johanna Inhyang Kim, Beomjun Min, Ji-Hye Lee, Heyeon Park, Jeong-Hyun Kim
Firefighters are an at-risk population for multiple psychiatric conditions, including posttraumatic stress disorder (PTSD), depression, alcohol use disorders (AUDs), and insomnia. These disorders are likely to co-occur; however, patterns of comorbidity have scarcely been investigated in firefighters. We aimed to identify subgroups of comorbidity of PTSD, depression, AUDs, and insomnia in a nationwide
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Association between low MCV in early pregnancy and perinatal mental health in the Japan Environment and Children's Study and the possible effect of iron deficiency J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-05 T. Ohsuga, M. Egawa, Y. Takahashi, Y. Ikeda, K. Tsuyuki, K. Kanatani, F. Niwa, K. Hirabayashi, T. Nakayama, M. Mandai, The Japan Environment and Children's Study Group
Postpartum anemia and iron deficiency are associated with postpartum depression. This study investigated the association between a low mean corpuscular volume (MCV) without anemia (which implies early-stage iron deficiency) in early pregnancy and perinatal mental health outcomes. The fixed data from the Japan Environment and Children's Study (JECS), a Japanese nationwide birth cohort, were used. Perinatal
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Corrigendum to “Effects of group acceptance and commitment therapy (ACT) on anxiety and depressive symptoms in adults: A meta-analysis” [J. Affect. Disord. 309 (2022) 297–308] J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-05 Michele Gomes Ferreira, Luciano Inácio Mariano, Junio Vieira de Rezende, Paulo Caramelli, Naoko Kishita
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Data-driven personalized medicine approaches to cognitive-behavioral therapy allocation in a large sample: A reanalysis of the ENRICHED study J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-04 Suzanne Catharina van Bronswijk, Jacqueline Howard, Lorenzo Lorenzo-Luaces
Although effective treatments for common mental health problems are available, individual responses to treatments are difficult to predict. Treatment efficacy could be optimized by targeting interventions using individual predictions of treatment outcomes. The aim of this study was to develop a prediction algorithm using data from one of the largest randomized controlled trials on psychological interventions
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Major depressive disorder recognition by quantifying EEG signal complexity using proposed APLZC and AWPLZC J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-04 Xianyun Kang, Xiaoya Liu, Sitong Chen, Wenquan Zhang, Shuang Liu, Dong Ming
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Impact of ketamine on incidence of postoperative depression: Re-analysis using a more targeted approach J. Affect. Disord. (IF 6.6) Pub Date : 2024-04-04 I-Wen Chen, Chia-Li Kao, Kuo-Chuan Hung