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Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion Physiol. Rev. (IF 33.6) Pub Date : 2024-04-25 Bernard Thorens
Glucose homeostasis is mainly under the control of the pancreatic islet hormones insulin and glucagon, which, respectively, stimulate glucose uptake and utilization by liver, fat, and muscle or glucose production by the liver. The balance between the secretion of these hormones is under the control of blood glucose concentrations. Indeed, pancreatic islet b-cells and a-cells can sense variations in
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Physiological Basis for Xenotransplantation from Genetically-Modified Pigs to Humans: A Review Physiol. Rev. (IF 33.6) Pub Date : 2024-03-22 Leigh Peterson, Magdi Yacoub, David Ayares, Kazuhiko Yamada, Daniel Eisenson, Bartley P. Griffith, Muhammad Mohiuddin, Will Eyestone, J. Craig Venter, Ryszard T. Smolenski, Martine Rothblatt
Physiological Reviews, Ahead of Print.
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Neurobiology and systems biology of stress resilience Physiol. Rev. (IF 33.6) Pub Date : 2024-03-14 Raffael Kalisch, Scott J. Russo, Marianne B. Müller
Physiological Reviews, Ahead of Print.
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Best Practices for Data Management and Sharing in Experimental Biomedical Research Physiol. Rev. (IF 33.6) Pub Date : 2024-03-07 Teresa Cunha-Oliveira, John P.A. Ioannidis, Paulo J. Oliveira
Physiological Reviews, Ahead of Print.
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The Ion Channels of Endomembranes Physiol. Rev. (IF 33.6) Pub Date : 2024-03-07 Meiqin Hu, Xinghua Feng, Qiang Liu, Siyu Liu, Fangqian Huang, Haoxing Xu
Physiological Reviews, Ahead of Print.
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Mechanisms of myosin II force generation. Insights from novel experimental techniques and approaches Physiol. Rev. (IF 33.6) Pub Date : 2024-03-07 Dilson E. Rassier, Alf Månsson
Physiological Reviews, Ahead of Print.
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Evolution, biomechanics, and neurobiology converge to explain selective finger motor control Physiol. Rev. (IF 33.6) Pub Date : 2024-02-22 Jing Xu, Firas Mawase, Marc H. Schieber
Physiological Reviews, Ahead of Print.
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Navigating the Multifaceted Intricacies of the Na+-Cl− cotransporter, a Highly Regulated and Key Effector in the Control of Hydromineral Homeostasis Physiol. Rev. (IF 33.6) Pub Date : 2024-02-08 Alexis V. Rioux, Thy-Rene Nsimba-Batomene, Samira Slimani, Nicolas AD Bergeron, Mathieu AM Gravel, Simon V Schreiber, Marie-Jeanne Fiola, Ludwig Haydock, Alexandre P. Garneau, Paul Isenring
Physiological Reviews, Ahead of Print.
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The hormonal control of parturition Physiol. Rev. (IF 33.6) Pub Date : 2024-02-08 Emily Hamburg-Shields, Sam Mesiano
Physiological Reviews, Ahead of Print.
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Hepatic Glucagon Action - Beyond Glucose Mobilization Physiol. Rev. (IF 33.6) Pub Date : 2024-02-01 Sarina Kajani, Rhianna C. Laker, Sarah Will, Ekaterina Ratkova, Christopher J. Rhodes
Physiological Reviews, Ahead of Print.
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Proteomics of the Heart Physiol. Rev. (IF 33.6) Pub Date : 2024-02-01 Oleg A. Karpov, Aleksandr Stotland, Koen Raedschelders, Blandine Chazarin, Lizhuo Ai, Christopher I. Murray, Jennifer E. Van Eyk
Physiological Reviews, Ahead of Print.
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Ceramides are Fuel Gauges on the Drive to Cardiometabolic Disease Physiol. Rev. (IF 33.6) Pub Date : 2024-02-01 Joseph L. Wilkerson, Sean M. Tatum, William L. Holland, Scott A. Summers
Physiological Reviews, Ahead of Print.
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The anterior chamber of the eye technology and its anatomical, optical and immunological bases Physiol. Rev. (IF 33.6) Pub Date : 2024-01-11 Shao-Nian Yang, Yue Shi, Per-Olof Berggren
Physiological Reviews, Ahead of Print.
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Timing and cause of olfactory deciliation in COVID-19 Physiol. Rev. (IF 33.6) Pub Date : 2024-01-11 Rafal Butowt, Christopher S. von Bartheld
Physiological Reviews, Volume 104, Issue 2, Page 589-590, April 2024.
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Computational modeling of cardiac electrophysiology and arrhythmogenesis Physiol. Rev. (IF 33.6) Pub Date : 2023-12-28 Natalia A. Trayanova, Aurore Lyon, Julie Shade, Jordi Heijman
Physiological Reviews, Ahead of Print.
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The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract Physiol. Rev. (IF 33.6) Pub Date : 2023-12-07 Olaf Perdijk, Rossana Azzoni, Benjamin J. Marsland
Physiological Reviews, Ahead of Print.
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Corrigendum for Eisner et al., volume 103, 2023, p. 2767–2845 Physiol. Rev. (IF 33.6) Pub Date : 2023-12-04
Physiological Reviews, Volume 104, Issue 1, Page 327-327, January 2024.
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Phosphodiesterases in heart and vessels- From Physiology to Diseases Physiol. Rev. (IF 33.6) Pub Date : 2023-11-16 Qin Fu, Ying Wang, Chen Yan, Yang K. Xiang
Physiological Reviews, Ahead of Print.
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Editorial on Davis et al. Physiol. Rev. (IF 33.6) Pub Date : 2023-11-09 Brooke R. Shepley, Anthony R. Bain
Physiological Reviews, Ahead of Print.
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Cannabinoid treatments in epilepsy and seizure disorders Physiol. Rev. (IF 33.6) Pub Date : 2023-10-26 Orrin Devinsky, Nicholas A. Jones, Mark O. Cunningham, B. Ashan P. Jayaskera, Sasha Devore, Benjamin J. Whalley
Physiological Reviews, Ahead of Print.
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CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease Physiol. Rev. (IF 33.6) Pub Date : 2023-10-26 Jan F.C. Glatz, Lisa C. Heather, Joost J.F.P. Luiken
Physiological Reviews, Ahead of Print.
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Netosis creates a link between diabetes and Long COVID Physiol. Rev. (IF 33.6) Pub Date : 2023-10-19 Alain R. THIERRY
Physiological Reviews, Ahead of Print.
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Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease Physiol. Rev. (IF 33.6) Pub Date : 2023-10-16 Marzia Perluigi, Fabio Di Domenico, D. Allan Butterfield
Physiological Reviews, Volume 104, Issue 1, Page 103-197, January 2024.
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Multiscale Structure and Function of the Aortic Valve Apparatus Physiol. Rev. (IF 33.6) Pub Date : 2023-09-21 Hussam El-Nashar, Malak Sabry, Yuan-Tsan Tseng, Nadine Francis, Najma Latif, Kim H. Parker, James E. Moore, Magdi H. Yacoub
Physiological Reviews, Ahead of Print.
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Glucocorticoids, Their Uses, Sexual Dimorphisms, and Diseases: New Concepts, Mechanisms, and Discoveries Physiol. Rev. (IF 33.6) Pub Date : 2023-09-21 Genesee J Martinez, Malik Appleton, Zachary A. Kipp, Analia S. Loria, Booki Min, Terry D Hinds
Physiological Reviews, Ahead of Print.
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Tissue Transglutaminase: A Multifunctional and Multisite Regulator in Health and Disease Physiol. Rev. (IF 33.6) Pub Date : 2023-09-15 Zhouzhou Yao, Yuhua Fan, Lizhen Lin, Rodney E. Kellems, Yang Xia
Physiological Reviews, Ahead of Print.
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SIRT7: the seventh key to unlocking the mystery of aging Physiol. Rev. (IF 33.6) Pub Date : 2023-09-07 Umar Raza, Xiaolong Tang, Zuojun Liu, Baohua Liu
Physiological Reviews, Ahead of Print.
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New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN Physiol. Rev. (IF 33.6) Pub Date : 2023-08-24 Arnaud Monteil, Adriano Senatore, Antonio Gil-Nagel, Paloma Parra-Diaz, Philippe Lory, Nathalie C. Guérineau
Physiological Reviews, Ahead of Print.
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Community-Acquired Bacterial Co-infections and COVID-19 Physiol. Rev. (IF 33.6) Pub Date : 2023-08-17 Michael John Patton, Amit Gaggar, Matthew Might, Nathaniel Erdmann, Carlos J. Orihuela, Kevin S. Harrod
Physiological Reviews, Ahead of Print.
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Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing Physiol. Rev. (IF 33.6) Pub Date : 2023-08-17 Stéphanie Barrère-Lemaire, Anne Vincent, Christian Jorgensen, Christophe Piot, Joël Nargeot, Farida Djouad
Physiological Reviews, Ahead of Print.
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The Role of Quality Metrics in the Evolution of AI in Healthcare and Implications for Generative AI Physiol. Rev. (IF 33.6) Pub Date : 2023-08-10 Ryan C. Godwin, Ryan L. Melvin
Physiological Reviews, Ahead of Print.
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Recent Insights into Channelopathies Physiol. Rev. (IF 33.6) Pub Date : 2023-08-10 Osama F. Harraz, Eric Delpire
Physiological Reviews, Ahead of Print.
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Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract Physiol. Rev. (IF 33.6) Pub Date : 2023-08-10 Kenton M. Sanders, Bernard T. Drumm, Caroline A. Cobine, Salah A. Baker
Physiological Reviews, Ahead of Print.
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Lung Endothelium, Tau, and Amyloids in Health and Disease Physiol. Rev. (IF 33.6) Pub Date : 2023-08-10 Ron Balczon, Mike T. Lin, Sarah Voth, Amy R. Nelson, Jonas C. Schupp, Brant M. Wagener, Jean-Francois Pittet, Troy Stevens
Physiological Reviews, Ahead of Print.
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Sex Differences in Blood Pressure Regulation and Hypertension: Renal, Hemodynamic, and Hormonal Mechanisms Physiol. Rev. (IF 33.6) Pub Date : 2023-07-21 Erika R. Drury, Jing Wu, Joseph C. Gigliotti, Thu H. Le
Physiological Reviews, Ahead of Print.
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Obstructive nephropathy and molecular pathophysiology of renal interstitial fibrosis Physiol. Rev. (IF 33.6) Pub Date : 2023-07-13 Rikke Nørregaard, Henricus A.M. Mutsaers, Jorgen Frøkiær, Tae-Hwan Kwon
Physiological Reviews, Ahead of Print.
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Sympathetic circuits regulating hepatic glucose metabolism, where we stand Physiol. Rev. (IF 33.6) Pub Date : 2023-07-13 Andrea Zsombok, Lucie D Desmoulins, Andrei V Derbenev
Physiological Reviews, Ahead of Print.
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The Conducted Vasomotor Response and the Principles of Electrical Communication in Resistance Arteries Physiol. Rev. (IF 33.6) Pub Date : 2023-07-06 Galina Yu. Mironova, Paulina M. Kowalewska, Mohammed El-Lakany, Cam Ha T. Tran, Maria Sancho, Anil Zechariah, William F. Jackson, Donald G. Welsh
Physiological Reviews, Ahead of Print.
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Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions Physiol. Rev. (IF 33.6) Pub Date : 2023-06-29 Michael D. Roberts, John J. McCarthy, Troy A. Hornberger, Stuart M. Phillips, Abigail L. Mackey, Gustavo A. Nader, Marni D. Boppart, Andreas N. Kavazis, Paul T. Reidy, Riki Ogasawara, Cleiton A. Libardi, Carlos Ugrinowitsch, Frank W. Booth, Karyn A. Esser
Physiological Reviews, Ahead of Print.
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Mechanisms of SARS-CoV-2 Associated Anosmia Physiol. Rev. (IF 33.6) Pub Date : 2023-06-21 Tatsuya Tsukahara, David H. Brann, Sandeep Robert Datta
Physiological Reviews, Ahead of Print.
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Climate Change Impacts on Respiratory Health: Exposure, Vulnerability, and Risk Physiol. Rev. (IF 33.6) Pub Date : 2023-06-16 Hannah H. Covert, Firoz Abdoel Wahid, Sally E. Wenzel, Maureen Y. Lichtveld
Physiological Reviews, Ahead of Print.
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Physiology of intracellular calcium buffering Physiol. Rev. (IF 33.6) Pub Date : 2023-06-16 David Eisner, Erwin Neher, Holger Taschenberger, Godfrey Smith
Physiological Reviews, Ahead of Print.
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The Physiology of Sedentary Behavior Physiol. Rev. (IF 33.6) Pub Date : 2023-06-16 Ana J. Pinto, Audrey Bergouignan, Paddy C. Dempsey, Hamilton Roschel, Neville Owen, Bruno Gualano, David W. Dunstan
Physiological Reviews, Ahead of Print.
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Synaptic memory and CaMKII: a review Physiol. Rev. (IF 33.6) Pub Date : 2023-06-08 Roger A. Nicoll, Howard Schulman
Physiological Reviews, Ahead of Print.
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Making a good egg: human oocyte health, aging and in vitro development Physiol. Rev. (IF 33.6) Pub Date : 2023-05-12 Evelyn Elizabeth Telfer, Johanne Grosbois, Yvonne L. Odey, Roseanne Rosario, Richard A. Anderson
Physiological Reviews, Ahead of Print.
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The placenta: Epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health Physiol. Rev. (IF 33.6) Pub Date : 2023-05-12 Myriam Hemberger, Wendy Dean
Physiological Reviews, Ahead of Print.
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Leveraging Physiology and Artificial Intelligence to Deliver Advancements in Healthcare Physiol. Rev. (IF 33.6) Pub Date : 2023-04-27 Angela Zhang, Zhenquin Wu, Eric Wu, Matthew Wu, Michael P. Snyder, James Zou, Joseph C. Wu
Physiological Reviews, Ahead of Print.
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Mitochondria in Health, Disease, and Ageing Physiol. Rev. (IF 33.6) Pub Date : 2023-04-06 John S. Harrington, Stefan W. Ryter, Maria Plataki, David R. Price, Augustine M.K. Choi
Physiological Reviews, Ahead of Print.
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Bioenergetics: The Evolutionary Basis of Progressive Kidney Disease Physiol. Rev. (IF 33.6) Pub Date : 2023-03-30 Robert L. Chevalier
Physiological Reviews, Ahead of Print.
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The human periconceptional maternal-embryonic space in health and disease Physiol. Rev. (IF 33.6) Pub Date : 2023-02-16 Inmaculada Moreno, Antonio Capalbo, Aymara Mas, Tamara Garrido-Gomez, Beatriz Roson, Maurizio Poli, Eva Dimitriadis, Xavier Santamaria, Felipe Vilella, Carlos Simon
Physiological Reviews, Ahead of Print.
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Membrane Adhesion Junctions Regulate Airway Smooth Muscle Function and Phenotype Physiol. Rev. (IF 33.6) Pub Date : 2023-02-16 Wenwu Zhang, Yidi Wu, Susan Gunst
Physiological Reviews, Ahead of Print.
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The long-term variability of human health related solar ultraviolet-B radiation doses for the 1980s to the end of 21st century Physiol. Rev. (IF 33.6) Pub Date : 2023-02-14 Christos Zerefos, Ilias Fountoulakis, Kostas Eleftheratos, Andreas Kazantzidis
Physiological Reviews, Ahead of Print.
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The multiple roles of salt-inducible kinases in regulating physiology Physiol. Rev. (IF 33.6) Pub Date : 2023-02-02 Aarti Jagannath, Lewis Taylor, Yining Ru, Zeinab Wakaf, Kayomavua Akpobaro, Sridhar Vasudevan, Russell G. Foster
Physiological Reviews, Ahead of Print.
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The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes Physiol. Rev. (IF 33.6) Pub Date : 2023-02-02 Morten S. Nielsen, Chantal J.M. van Opbergen, Toon A.B. van Veen, Mario Delmar
Physiological Reviews, Ahead of Print.
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Mesenchymal Condensation in Tooth Development and Regeneration: a Focus on Translational Aspects of Organogenesis Physiol. Rev. (IF 33.6) Pub Date : 2023-01-19 Bing-Dong Sui, Chen-Xi Zheng, Wan-Min Zhao, Kun Xuan, Bei Li, Yan Jin
The teeth are vertebrate-specific and highly specialized organs performing fundamental functions of mastication and speech, the maintenance of which is crucial for orofacial homeostasis and is further linked to systemic health and human psychosocial well-being. However, with limited ability of self-repair, the teeth can often be impaired by traumatic, inflammatory and progressive insults, leading to
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Genome-wide association studies of cardiovascular disease Physiol. Rev. (IF 33.6) Pub Date : 2023-01-12 Roddy Walsh, Sean J. Jurgens, Jeanette Erdmann, Connie R. Bezzina
Genome-wide association studies (GWAS) aim to identify common genetic variants that are associated with traits and diseases. Since 2005, more than 5,000 GWAS have been published for almost as many traits. These studies have offered insights into the loci and genes underlying phenotypic traits, highlighted genetic correlations across traits and diseases and are beginning to demonstrate clinical utility
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Examining the shared etiology of psychopathology with genome-wide association studies Physiol. Rev. (IF 33.6) Pub Date : 2023-01-12 Travis T. Mallard, Andrew D. Grotzinger, Jordan W. Smoller
Genome-wide association studies (GWASs) have ushered in a new era of reproducible discovery in psychiatric genetics. The field has now identified hundreds of common genetic variants that are associated with mental disorders - many of which influence more than one disorder. By advancing understanding of causal biology underlying psychopathology, GWAS results are poised to inform the development of novel
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Vascular Mechanotransduction Physiol. Rev. (IF 33.6) Pub Date : 2023-01-05 Michael J. Davis, Scott Earley, Yi-Shuan Li, Shu Chien
This review aims to survey the current state of mechanotransduction in vascular smooth muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical stimuli and transduction of mechanical signals that result in the acute functional modulation and longer-term transcriptomic and epigenetic regulation of blood vessels. The mechanosensors discussed include ion channels, plasma
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Comparative Physiological Anthropogeny: Exploring Molecular Underpinnings of Distinctly Human Phenotypes Physiol. Rev. (IF 33.6) Pub Date : 2023-01-05 Michael Vaill, Kunio Kawanishi, Nissi Varki, Pascal Gagneux, Ajit Varki
Anthropogeny is a classic term encompassing transdisciplinary investigations of the origins of the human species. Comparative Anthropogeny is a systematic comparison of humans and other living non-human hominids (so-called "Great Apes"), aiming to identify distinctly human features in health and disease, with the overall goal of explaining human origins. We begin with a historical perspective, briefly
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The molecular athlete: exercise physiology from mechanisms to medals Physiol. Rev. (IF 33.6) Pub Date : 2023-01-05 Regula Furrer, John A. Hawley, Christoph Handschin
Physiological Reviews, Ahead of Print.