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Optimization of peptide synthesis time and sustainability using novel eco‐friendly binary solvent systems with induction heating on an automated peptide synthesizer J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-25 Lorenzo Pacini, Manoj Muthyala, Luisa Aguiar, Robert Zitterbart, Paolo Rovero, Anna Maria Papini
On December 12th, 2023, the European Commission took regulatory action to amend Annex XVII of REACH, imposing restrictions on the use of N,N‐dimethylformamide (DMF) within the EU market owing to its high toxicity. Historically, DMF has been widely considered the gold standard for solid‐phase peptide synthesis (SPPS). Being urgent to propose alternative solvents, we tested the suitability of non‐hazardous
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Investigating the impact of thiol reactivity and disulfide formation on cellular uptake of cell‐permeable peptides J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-23 Merlin Klußmann, Katharina Stillger, Melina Ruppel, Coco‐Louisa Sticker, Ines Neundorf
Cell‐penetrating peptides (CPPs) have been explored as versatile tools to transport various molecules into cells. The uptake mechanism of CPPs is still not clearly understood and most probably depends on several factors like the nature of the CPP itself, the attached cargo, the investigated cell system, and other experimental conditions, such as temperature and concentration. One of the first steps
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Design and synthesis of peptides as stabilizers of histone deacetylase 4 J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-16 Annika Lill, Markus Schweipert, Thomas Nehls, Eva Wurster, Frederik Lermyte, Franz‐Josef Meyer‐Almes, Katja Schmitz
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Genetically encoded libraries and spider venoms as emerging sources for crop protective peptides J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-16 Elena Marone Fassolo, Shaodong Guo, Yachen Wang, Stefano Rosa, Volker Herzig
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Peptide‐drug conjugate designated for targeted delivery to HER2‐expressing cancer cells J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-11 Amit Kumar Sharma, Rohit Sharma, Nitish Chauhan, Amit Das, Drishty Satpati
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Designer tryptophan‐rich peptide modulates structural dynamics of HIF‐1α DNA i‐motif DNA J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-09 Debasis Ghosh, Sumon Pratihar, Thimmaiah Govindaraju
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-04
No abstract is available for this article.
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The bright side of chemistry: Exploring synthetic peptide‐based anticancer vaccines J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-04 Antonia D'Aniello, Alessandra Del Bene, Salvatore Mottola, Vincenzo Mazzarella, Roberto Cutolo, Erica Campagna, Salvatore Di Maro, Anna Messere
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Impact of glycan nature on structure and viscoelastic properties of glycopeptide hydrogels J. Pept. Sci. (IF 2.1) Pub Date : 2024-04-03 Jonas Proksch, Marlene C. S. Dal Colle, Frederick Heinz, Robert F. Schmidt, Jacqueline Gottwald, Martina Delbianco, Bettina G. Keller, Michael Gradzielski, Ulrike Alexiev, Beate Koksch
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Bergofungin D, a peptaibol template for the introduction of chemical modifications, synthesis of analogs and comparative studies of their structures J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-26 Sanjit Das, Khoubaib Haj Ben Salah, Emmanuel Wenger, Baptiste Legrand, Claude Didierjean, Nicolas Inguimbert
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Workshop: Sorrento 2013 – Sorrento 2023 A decade of Peptide Materials J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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Extract from the Minutes of the EC Meeting, 22 and 23 of March 2023 (Videoconference) J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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Extract from the Minutes of the Meeting of the International Liaison Committee (ILC) J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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10th International Peptide Conference of the Bulgarian Peptide Society J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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23rd meeting of the French Peptides and Proteins Group (GFPP) J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
No abstract is available for this article.
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10th International Meeting on Antimicrobial Peptides (IMAP) J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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Extract from the Minutes of the General Assembly of the European Peptide Society of May 12, 2023 J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-27
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N‐terminal modification of an LAH4‐derived peptide increases mRNA delivery in the presence of serum J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-25 Candice Dussouillez, Morane Lointier, Mohammed‐Karim Sebane, Sylvie Fournel, Burkhard Bechinger, Antoine Kichler
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Supercharged coiled‐coil protein with N‐terminal decahistidine tag boosts siRNA complexation and delivery efficiency of a lipoproteoplex J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-19 Jonathan W. Sun, Joseph S. Thomas, Julia M. Monkovic, Halle Gibson, Akash Nagapurkar, Joseph A. Frezzo, Priya Katyal, Kamia Punia, Farbod Mahoudinobar, P. Douglas Renfrew, Jin Kim Montclare
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Wound microenvironment‐responsive peptide hydrogel with multifunctionalities for accelerating wound healing J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-18 Weimiao Dong, Haihong Yang, Min Liu, Leixia Mei, Jun Han
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-16
No abstract is available for this article.
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Hybrid peptide-PNA monomers as building blocks for the fabrication of supramolecular aggregates J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-12 Luca Cimmino, Carlo Diaferia, Mariangela Rosa, Giancarlo Morelli, Elisabetta Rosa, Antonella Accardo
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Towards targeted Cas9 (CRISPR‐Cas) delivery: Preparation of IgG antibody‐Cas9 conjugates using a split intein J. Pept. Sci. (IF 2.1) Pub Date : 2024-03-06 Tim Pasch, Nicole Bäumer, Sebastian Bäumer, Frank Buchholz, Henning D. Mootz
The CRISPR‐Cas9 system has revolutionized the field of genetic engineering, but targeted cellular delivery remains a central problem. The delivery of the preformed ribonuclease‐protein (RNP) complex has the advantages of fewer side effects and avoidance of potential permanent effects. We reasoned that an internalizing IgG antibody as a targeting device could address the delivery of Cas9‐RNP. We opted
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Isolation and antioxidant activity of peptides from Chinese hairy tofu J. Pept. Sci. (IF 2.1) Pub Date : 2024-02-24 Li‐Ping Wu, Yong‐Xiang Wu, Xiang‐Tao Ke, Pan Wang, Shuo Zhang, Yu‐Ting Zhu, Ying Lu, Yu‐Jie Shu, Shang‐Yue Jiang, Chang‐Jiang Li, Xiao‐Qian Hu
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Small molecule– and peptide–drug conjugates addressing integrins: A story of targeted cancer treatment J. Pept. Sci. (IF 2.1) Pub Date : 2024-02-21 Jannik Paulus, Norbert Sewald
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Comparison of the self‐assembly and cytocompatibility of conjugates of Fmoc (9‐fluorenylmethoxycarbonyl) with hydrophobic, aromatic, or charged amino acids J. Pept. Sci. (IF 2.1) Pub Date : 2024-02-20 Valeria Castelletto, Lucas de Mello, Emerson Rodrigo da Silva, Jani Seitsonen, Ian W. Hamley
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Detailed investigation of the binding abilities of the heterodomain of a multiHis cyclopeptide toward Cu(II) ions J. Pept. Sci. (IF 2.1) Pub Date : 2024-02-05 Marco Bortolus, Aleksandra Kotynia, Giacomo Saielli, Paolo Ruzza, Marilena Di Valentin, Mauro Carraro, Justyna Brasuń
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2024-02-05
No abstract is available for this article.
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Total synthesis of antifungal lipopeptide iturin A analogues and evaluation of their bioactivity against F. graminearum J. Pept. Sci. (IF 2.1) Pub Date : 2024-02-01 Periklis Karamanis, Jimmy Muldoon, Cormac D. Murphy, Marina Rubini
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All-hydrocarbon stapling enables improvement of antimicrobial activity and proteolytic stability of peptide Figainin 2 J. Pept. Sci. (IF 2.1) Pub Date : 2024-01-25 Jingwen Xue, Yinxue Fu, Huang Li, Ting Zhang, Wei Cong, Honggang Hu, Zhiyuan Lu, Fang Yan, Yulei Li
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Identification, chemical synthesis, and receptor binding of a reptilian gecko ghrelin J. Pept. Sci. (IF 2.1) Pub Date : 2024-01-24 Hidekazu Katayama, Hiroyuki Kaiya
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Non-canonical amino acid bioincorporation into antimicrobial peptides and its challenges J. Pept. Sci. (IF 2.1) Pub Date : 2024-01-23 George Nkrumah Enninful, Rajesh Kuppusamy, Elvis K. Tiburu, Naresh Kumar, Mark D. P. Willcox
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Design, synthesis, and analysis of macrobicyclic peptides for targeting the Gαi protein J. Pept. Sci. (IF 2.1) Pub Date : 2024-01-17 Anna Pepanian, F. Ayberk Binbay, Dehua Pei, Diana Imhof
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Solid-phase peptide synthesis in 384-well plates J. Pept. Sci. (IF 2.1) Pub Date : 2024-01-14 Mischa Schüttel, Edward Will, Gontran Sangouard, Anne Zarda, Sevan Habeshian, Alexander L. Nielsen, Christian Heinis
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2024-01-07
No abstract is available for this article.
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Development of stapled NONO-associated peptides reveals unexpected cell permeability and nuclear localisation J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-26 Reginald Young, Tiancheng Huang, Zijie Luo, Yaw Sing Tan, Amandeep Kaur, Yu Heng Lau
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Identification, synthesis, and characterization of an unprecedented N-(2-carboxyethyl) adduct impurity in an injectable ganirelix formulation J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-22 Rohit Jadav, Ramraj Kameriya, Saurav Chatterjee, Vinod Gour, Parva Purohit, Anupam Bandyopadhyay
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Targeting Rab-RILPL interactions as a strategy to downregulate pathogenic LRRK2 in Parkinson's disease J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-22 Krista K. Alexander, Yahaira Naaldijk, Rachel Fasiczka, Besma Brahmia, Tiancheng Chen, Sabine Hilfiker, Eileen J. Kennedy
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Hydrophobicity: The door to drug delivery J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-19 Annarita Falanga, Rosa Bellavita, Simone Braccia, Stefania Galdiero
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Self-assembly of heterochiral, aliphatic dipeptides with Leu J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-18 Erica Scarel, Marco De Corti, Maurizio Polentarutti, Giovanni Pierri, Consiglia Tedesco, Silvia Marchesan
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-06
No abstract is available for this article.
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A library-derived peptide inhibitor of the BZLF1 transcription factor J. Pept. Sci. (IF 2.1) Pub Date : 2023-12-02 Sarah K. Madden, Andrew Brennan, Jody M. Mason
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Breaking down and building up alpha-synuclein: An insight on its N-terminal domain J. Pept. Sci. (IF 2.1) Pub Date : 2023-11-30 Kaliroi Peqini, Simone Attanasio, Lucia Feni, Graziella Cappelletti, Sara Pellegrino
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Antiviral peptides inhibiting the main protease of SARS-CoV-2 investigated by computational screening and in vitro protease assay J. Pept. Sci. (IF 2.1) Pub Date : 2023-11-29 James Stewart, Jakaria Shawon, Md Ackas Ali, Blaise Williams, A. D. A. Shahinuzzaman, Sharmin Akther Rupa, Taha Al-Adhami, Ruoqing Jia, Cole Bourque, Ryan Faddis, Kaylee Stone, Md Abu Sufian, Rajib Islam, Andrew C. McShan, Khondaker Miraz Rahman, Mohammad A. Halim
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Cysteine-free cone snail venom peptides: Classification of precursor proteins and identification of mature peptides J. Pept. Sci. (IF 2.1) Pub Date : 2023-11-27 Marimuthu Vijayasarathy, Sanjeev Kumar, Rajdeep Das, Padmanabhan Balaram
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Ernesto Scoffone: A great scientist, colleague, and mentor. J. Pept. Sci. (IF 2.1) Pub Date : 2023-11-05 Claudio Toniolo,Marta De Zotti
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Exploring biocompatible chemistry to create stapled and photoswitchable variants of the antimicrobial peptide aurein 1.2 J. Pept. Sci. (IF 2.1) Pub Date : 2023-11-05 Alexandra E. Coram, Richard Morewood, Saan Voss, Joshua L. Price, Christoph Nitsche
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Issue Information J. Pept. Sci. (IF 2.1) Pub Date : 2023-11-02
No abstract is available for this article.
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Antibacterial and in vitro anticancer activities of the antimicrobial peptide NRC-07 encapsulated in chitosan nanoparticles J. Pept. Sci. (IF 2.1) Pub Date : 2023-10-19 Nancy O. Turky, Noura A. Abdelmonem, Salma N. Tammam, Mohamed Z. Gad, Hans-Georg Breitinger, Ulrike Breitinger