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Sintering Driven Void Formation in PS@WO3 Core-Shell Composites: A Photodegradation Enhancement Strategy Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-04-22 Min Yen Yeh, Ruei Ying You, Po Wen Cheng, Shih-Syuan Hwang, Gui-Cheng Hu, Shun Hsyung Chang
Background: Polystyrene nanospheres are used as a substrate for the hydrothermal coating of tungsten trioxide (WO3) to form a core-shell composite of PS@WO3. The core-shell structure is used for the next sintering step. This produces porous WO3. The focus of this study is on the role of porous WO3 in enhancing photocatalytic performance. Methods: The hydrothermal method was employed for coating, and
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An Overview of Recent Analytical Techniques for Air Quality Monitoring and Assessment Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-04-16 Sa’adatu Eri Mohammed, Hamza Badamasi, Augustine A. Unimke, Naseer Inuwa Durumin Iya, Aderibigbe Deborah Olubunmi, Chinyere Okoro, Onyemaechi Okezie, Abdul Ademola Olaleye
: Access to clean air, a vital necessity for life, faces severe constraints globally due to industrialization and urbanization, leading to widespread air quality deterioration. To safeguard human health and the environment from detrimental effects, the essential components of proper monitoring, assessment, and management of air quality are paramount. Conventional air quality analytical techniques such
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Applicability of QbD-assisted Analytical Method for Simultaneous Detection of Tetrahydrocurcumin and Folic Acid in Developed Nanostructured Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-04-15 Parina Kumari, Sarwar Beg, Kamalinder K Singh, Vandita Kakkar
Aims:: Applicability of QbD-assisted analytical method for simultaneous detection of tetrahydrocurcumin and folic acid in developed nanostructured. background: Background: Diabetic foot ulcer (DFU), a multifactorial disorder involves chronic inflammation, oxidative stress and neuropathy. Current treatment therapies, involving the use of growth factors and skin substitutes being costly, are out of reach
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Local Structure and Optical Studies of Mn2+ Doped L-histidine-4-nitrophenolate 4-nitrophenol Single Crystal Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-04-04 Maroj Bharati, Vikram Singh, Ram Kripal
Background: The zero-field splitting parameters of Mn2+ doped L-histidine-4- nitrophenolate 4-nitrophenol single crystals are evaluated Methods: The superposition model and perturbation theory are used to obtain zero-field splitting parameters for Mn2+ ion-doped LHPP single crystals. The optical spectra of the system are computed using the crystal field parameters from the superposition model as input
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Silica-Based 1,3-Diphenyl-1,3-Propanedione Composites: Efficient Uranium Capture for Environmental Remediation Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-04-04 Mohammed A. Al-Anber, Wala Al-Qaisi, Idrees F. Al-Momani, Ahmed K. Hijazi, Dinara Sobola, Wasim Alhalasah, Zaid A. Al-Anber
Introduction:: This study synthesizes and characterizes a novel hybrid composite, SGdpm, to capture UO2 2+ ions from water. The composite has successfully formed by hosting covalently diphenylmethane-1,3-dione (dpm) within an inorganic silica gel matrix, showing promising potential for environmental remediation and nuclear waste management. Methods:: The preparation involved the reaction of tetraethylorthosilicate
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Practical Perspectives and Roles of XRD in Drug Discovery: A Review Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-04-04 Ashish Mehta, Rahul Makhija, Pallavi Barik, Shubham Dhiman, Ghanshyam Das Gupta, Vivek Asati
: Biophysical techniques include various methodologies applied in studying biological systems at the molecular and cellular level for the drug discovery process. Various methods like isothermal calorimetry, electron microscopy, XRD (X-ray diffraction), electron microscopy, mass spectrometry, atomic force microscopy, differential scanning calorimetry, surface plasmon resonance, and nuclear magnetic
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Biosensor Based on Zif-8-905% Metal-organic Nanocomposite and Carbon Nanotubes Associated with Concanavalin a for Detection of Alpha-fetoprotein Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-29 Aiany Maria Queiroz Felix, Severino Alves Júnior, Alberto Galdino da Silva Júnior, Michelly Cristiny Pereira, Maria Danielly Lima Oliveira, César Augusto Souza de Andrade
Introduction:: Lung carcinoma presents an aggressive evolution, with its carriers having reduced survival. Late diagnosis is one of the main factors of death. In the neoplasia in question, there is an established correlation with increases in Alpha-Fetoprotein (AFP) serum concentrations. Method:: Commonly used diagnostic methods are invasive or inaccessible. Therefore, a low-cost, non-invasive method
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Application of a Green Deep Eutectic Solvent for Preconcentration and Determination of Copper and Cadmium in Food, Cosmetic, and Water Samples Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-29 Hamidreza Haghgoo Qezelje, Maryam Rajabi, Erfan Parsa, Sayeh Ghanbari Adivi, Mehrnaz Shahi, Alireza Asghari, Mohammad Bazregar, Ahmad Hosseini-Bandegharaei
Background:: Determination of environmental pollutants is important due to their harmful effects on the health of living organisms. However, direct measurement of many of these pollutants is not possible due to their low concentrations, which necessitates the need for sample preparation methods. One of the rapid and simple sample preparation methods is the Air-Agitated Liquid-Liquid Microextraction
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A Review of Minimally and Non-invasive Glucose Monitoring Techniques, Devices and Sensors Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-29 Mohammad Nooshnab, Seyed Morteza Naghib, Rouhollah Rahmanifard, Elnaz Khakpour
: Glucose determination, without pain and aches, is essential for biomedical applications. Minimally invasive (MI) and non-invasive (NI) are the approaches that could address these challenges. MI approaches are based on body fluids such as saliva, urine, tears, and interstitial fluid that are exploited to determine glucose levels. NI methods utilize radiation forms to determine glucose concentration
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Emerging Technologies for Sensitive Detection of Organophosphate Pesticides: A Review Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-28 A. Kumaravel, S. Aishwarya, S. Sathiyamoorthi
: The use of organophosphate pesticides (OPPs) in agricultural practices improves crop yield and controls pests, but their indiscriminate use and persistence in the environment pose significant health risks. Therefore, it has become increasingly important to develop reliable and efficient detection methods for OPPs to ensure food safety and monitor their presence. In recent years, OPP detection methods
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Development of UV Method for Simultaneous Estimation of Imipramine and Ferulic Acid in Bulk and Developed Freeze-Dried Mixed Micelles Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-28 Naman Deep Raj, Dilpreet Singh
Introduction:: A simple, precise, and sensitive UV spectrophotometric method was developed to estimate Imipramine and Ferulic acid in bulk and polymeric micelles formulation. Moreover, imipramine and ferulic acid showed maximum absorbance at 237 nm and 216 nm. Method:: The method was validated for linearity, accuracy, precision, robustness, and ruggedness. The detector response for the imipramine and
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A Novel Electrochemiluminescence (ECL) Immunoassay for the Quantitation of Monoclonal Antibody (mAb) PYX-106 in Human Serum Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-28 Feng Yin, Diana Adhikari, Xiaodong F. Liu, Jianxin Wang, Wensheng Yang, Gabriela A. Balogh, Teri Simon, Wenji Lei, Mariana Squicciarini, Lisa Bruce, Yan Ke, Mike Dyszel, Shawn Harriman, Jan Pinkas
Background:: PYX-106 is a novel monoclonal antibody (mAb), targeting the sialic acidbinding immunoglobulin-like lectin 15 (Siglec-15) in the Tumor Microenvironment (TME). Precise measurement of PYX-106 is essential for the thorough assessment of PYX-106 pharmacokinetics in clinical investigations. Methods:: A novel Electrochemiluminescence (ECL) immunoassay for the quantitation of PYX- 106 in human
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Recent Advancements in Biochar and its Composite for the Remediation of Hazardous Pollutants Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-26 Akshay Verma, Gaurav Sharma, Amit Kumar, Pooja Dhiman, F. J. Stadler
: Biochar has garnered considerable attention in recent times due to its potential uses in the environmental field. In this study, we comprehensively examine and condense information on biochar production, characteristics, and adsorption mechanisms, with a focus on its economic applications for remediating hazardous contaminants. Our assessment is based on over 200 publications from the past decade
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Ag-TiO2 Photovoltaic Synergistic Field-catalyzed Degradation Performance of Tetracycline Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-21 Qirui Wang, Xian Liu, Ziqi Qin, Xiang Ge, Chengcheng Li, Lei Zhu, Xun Wang
Background: Tetracycline (TC), a commonly used antibiotic, is extensively utilized in the medical sector, leading to a significant annual discharge of tetracycline effluent into the water system, which harms both human health and the environment. background: Tetracycline (TC), a commonly used antibiotic, is extensively utilized in the medical sector, leading to a significant annual discharge of tetracycline
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Smartphone-Based Colourimetric Detection of Methyl Red, Co(II), Uric Acid, and Topotecan after Pre-concentration onto a Hectorite Clay-Hydroxyethylcellulose Hybrid Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-20 Anastasios Phoebus Mazarakis, Georgia Eleni Tsotsou
Objective: This paper describes a new, digital image colourimetry-based format for the quantification of analytes in an aqueous solution. Method: The proposed method is based on analyte pre-concentration by adsorption onto Bentone LT. Bentone LT pellet isolation comes after adsorption, followed by in-situ application of an analyteselective chromogenic reaction. The resulting pellet colouration is captured
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Paper-based Microfluidic Devices for the Analysis of Various Pathogens from Diverse Samples Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-14 Namita Ashish Singh, Nitish Rai, Ashish Kumar Singh, Vidhi Jain, Jagriti Narang
: In today’s era, detection of disease is utmost important for the management of disease. Early detection leads to early management of disease. Paper-based microfluidic devices are promising technologies that are cost-effective, portable and easy to use over conventional methods. In addition, paper-based microfluidics offers low reagent/sample volume, less response time and can be used in resource-limited
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Advancing Diagnostics: Evaluating the Potential of Nanoparticle-Based Immunoassays as PCR Alternatives for Disease Confirmation Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-11 Aditya Kurdekar, Venkataramaniah Kamisetti
In diagnostic technologies, search for quick, accurate, and cost-efficient ways to confirm diseases has prompted the investigation of alternative methodologies to classic PCR-based tests. This article delves into the growing field of nanoparticle-based immunoassays, offering a comprehensive evaluation of their potential as viable alternatives to PCR for disease diagnostics. We discuss the basic principles
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Hydrophilic Interaction Liquid Chromatography for the Analysis of Pharmaceutical Formulations Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-08 Aleksandra Radoičić, Sandra Šegan, Aleksandra Dramićanin, Dušanka Milojković-Opsenica
For a long time, Reversed-Phase Liquid Chromatography (RPLC) was the most dominant technique for the analysis of pharmaceutical compounds, but with poor efficiency in the separation of small polar molecules. From the efforts to solve the problem of insufficient retention of these molecules, during the last decades, a mode of liquid chromatography named Hydrophilic Interaction Liquid Chromatography
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Sorption Efficacy of Weathered Basalt Rock for Metal Ions of Nuclear Importance Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-08 Harshala Parab, Rahul Sirvi, Shrutika Kadam, Pranesh Sengupta, Sangita D. Kumar, Uttam K. Bhui
Background: A safe and long-term isolation of radionuclides is crucial for efficient waste management in the nuclear fuel cycle. Clay minerals of geological origin are considered candidate barrier materials for the sequestration of nuclear waste for geological disposal applications. Objective: The present study encompasses a systematic characterization of weathered basalt rock and the influence of
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A Study on the Anti-inflammatory Activity of Clematis tangutica Using Molecular Networking Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-08 Aijing Li, Tao Chen, Shuo Wang, Juyuan Luo, Cheng Shen, Hongmei Li, Yumei Ma, Zhibo Song, Weihang Lu, Denglang Zou, Yulin Li
Background:: Clematis tangutica, an indigenous medicinal herb native to the Qinghai- Tibet Plateau of China, has traditionally been associated with treating various inflammation-related diseases. While its therapeutic potential is recognized, a comprehensive characterization of its metabolite molecules and their anti-inflammatory properties has not been undertaken. Objective:: This study aimed to comprehensively
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Citrus Essential Oils as Potential Insecticides Against Thrips flavus Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-03-01 Tian-hao Pei, Yu-Long Niu, Bin Liu, Ming Yuan, Ai-Guo Zhang, Xiao-Feng Li, Lian-Xia Wang, Meng-Lei Xu, Yu Gao
Background: Essential oils (EOs) are recognized for their potent insecticidal activity and are widely considered promising agents for pest control. Methods: The insecticidal activity of seven commercial citrus EOs against the global phytophagous pest Thrips flavus was evaluated using bioassays conducted under laboratory conditions. Moreover, the chemical composition of these EOs was analyzed using
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Effects of Salvianolate Injection on the Pharmacodynamics and Pharmacokinetics of Warfarin in Rats In vivo Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-29 Yue Zhao, Jiahui Sun, Shiwei Xu, Yan Liu, Mengnan Qin, Chunjuan Yang, Gaofeng Liu
Background: Both Salvianolate Injection and warfarin are widely prescribed in patients with cardiovascular diseases, but the interaction between them is unknown and needs to be investigated. Objective: This research aims to study the effects and mechanism of Salvianolate Injection on the pharmacodynamics and pharmacokinetics of warfarin in rats. Methods: Male Wistar rats were intraperitoneally injected
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Magnetite Reduced Graphene Oxide/Ordered Mesoporous Carbon Nanocomposite as Effective Adsorbent for Removal of 2-Naphthol in Wastewater Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-27 Fatemeh Chaltash, Fereshteh Chekin, Seyed Mohammad Vahdat
Background: The wastewater released from various industries contains substantial amounts of organic compounds such as dyes and naphthols. However, naphthols are toxic to the environment and human health. So, it is essential to eliminate them, which will contribute to manufacturing and environmental management. Methods: In the work, an eco-friendly method is adapted to synthesize reduced graphene oxide
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Influence of the Presence of Sulfur and Oxygen Atoms on Molecular, Thermodynamic and Transport Properties in Hydrocarbon Mixtures Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-26 Josue Francisco Perez-Sanchez, Ruth del Carmen Galindo-Lopez, Edgardo Jonathan Suarez Dominguez, Jpsé Rafael Rodriguez-Rodriguez, Yoana Perez-Badell, Elena Francisco Izquierdo Kulich
Introduction: Crude oil is a complex blend of various hydrocarbon families, with compositions that vary depending on the source well and exploitation duration. To categorize its constituents, SARA analysis divides them into saturated, aromatic, resins, and asphaltenes. Heavy asphaltene- rich crude oils can present challenges like viscosity and pipeline blockages, which are often addressed with viscosity-reducing
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Extraction Optimization, Structure Analysis and Antioxidant Activity of Polysaccharide from Sanghuangporus baumii Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-26 Yunhe Qu, Pingping Zhang, Jing Cui, Xiuzhen Ni, Kai Song, Dongfang Shi
Introduction: In this study, we optimized the extraction process, analyzed the structure and assessed the antioxidant activity of Sanghuangporus baumii polysaccharide (SBP). The present results provide important information for the Sanghuangporus baumii polysaccharides in potential natural antioxidant effects. Background: The extraction and structural analysis of polysaccharides from Sanghuangporus
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HPLC-MS/MS Method for the Quantitative Determination of Metformin in Rat Plasma and Its Application to Comparative Bioavailability Assessment Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-15 Di-Di Zhang, Young-Heun Jung, Mi-Ji Seol, Siyu Zhou, Dinesh Chaudhary, Jee-Heon Jeong, Ju-Hyun Kim
Background: Metformin is a biguanide derivative utilized as a first-line treatment for type 2 diabetes for people over 60 years. However, it faces certain limitations due to its incomplete absorption, resulting in a 50-60% bioavailability. In addition to its blood glucose-lowering effect, the antiproliferative effect of metformin has been demonstrated in vitro. Therefore, it is necessary to consider
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Design and Fabrication of Silver Nanoparticles Doped β-cyclodextrin-chitosan Functionalized Graphene Nanocomposite Modified Electrode for Determination of Cu(II) Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-13 Abdullah Akhdhar, Mona Saad Binkadem, Waleed Ahmed El-Said, Amr A. Yakout
Introduction: In this study, a nanocomposite film was prepared by doping silver nanoparticles onto β-cyclodextrin-chitosan functionalized Reduced Graphene Oxide (RGO), denoted as Ag/ β-CD/CS/G nanocomposite. The average diameter of the Ag NPs was found to be 62±17 nm. Method: The fabricated composite was applied to monitor trace levels of copper ions in different industrial and environmental water
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Development of an Indirect ELISA for the Detection of Lactoferrin in Type 2 Diabetes Plasma: A Novel Approach Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-09 Amani Alhalwani
Background: In biological systems, lactoferrin (LF) is a crucial protein for protecting the body against diseases and pathogens that can affect both humans and animals. LF is a multifunction protein that binds to different surface receptors to stimulate the innate immune system. In diabetes, lactoferrin has a direct association with inflammation. The effects of inflammation interaction are unknown
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Research Progress in the Detection of Aflatoxin B1 Based on Aptamers Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-07 Yi Zhang, Xiaofang Chen, Xiaoyi Xie, Dong Li, Yuxiu Fan, Bin Huang, Xiupei Yang
Aflatoxin B1 is highly toxic, mutagenic, teratogenic, and carcinogenic and is a class I carcinogen. Peanuts, cotton, and corn may be affected by AFB1 during cultivation, which can seriously jeopardize human health. Developing a simple, sensitive, and selective method for detecting AFB1 is imminent. Aptamers are obtained through in vitro screening of ligands by single-stranded oligonucleotides (DNA
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Quantitative Applications of ATR-FTIR Spectroscopy with Chemometrics for the Estimation of Amikacin in Amikacin Sulphate Injections Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-02-06 Chow Jie Chen, Bontha Venkata Subrahmanya Lokesh, Gabriel Akyirem Akowuah
Background: Amikacin belongs to the class of aminoglycoside antibiotics used in the treatment of gram-negative bacterial infections. It is resistant to the aminoglycosides modifying enzymes, making it a clinically effective drug in multidrug-resistant infections. Methods: In this study, a simple Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy was used for the quantification of
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Ultrasound-assisted Aqueous Two-Phase Extraction of Flavonoids from Scutellariae Radix and Evaluation of their Bioactivities In Vitro Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-30 Zhenkai Ge, Yongheng Zhao, Xu Ling, Chenpan Zhu, Xincai Hao
Background: Scutellariae Radix, one of the most widely used herbs in Traditional Chinese Medicine, exhibits various biological activities due to its chemical components, which stand out for a number of flavonoids. In this study, Ultrasound-assisted aqueous two-phase extraction (UAATPE) was employed for the first time to obtain a high extraction rate and high purity of flavonoids from Scutellariae Radix
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Rapid Determination of Diverse Ganoderic Acids in Ganoderma Using UPLC–MS/MS Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-30 Yan Yang, Yuying Jian, Bin Liu
Background: Ganoderma is known for its pharmaceutical, nutritional, and functional benefits. Its primary bioactive components are ganoderic acids. However, previous quantification methods only analyzed an individual or limited number of ganoderic acids. This study aims to develop a reliable method for simultaneously quantifying the major ganoderic acids to enhance Ganoderma quality control and study
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Heavy Metals in Blood Serum of Smokers and Non-smoking Controls Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-29 Abdulhussein Abdulameer Alkufi, Mohanad Hussain Oleiwi, Ali Abid Abojassim
Background: The analysis of heavy metals in the blood serum can serve as a reliable indicator for establishing the association between cigarette smoking and the presence of heavy metals. Methods: In this study, performed in Al-Najaf during 2023, concentrations of three heavy metals - cadmium (Cd), chromium (Cr), and lead (Pb) – were investigated in two groups: cigarette smokers, and non-smokers (the
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Construction of a Miniaturized Electrochemical Sensor for Voltammetric Detection of 17β-Estradiol Using a g-C3N4-Decorated Gold Nanoparticles Electrode Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-29 Yue Ma, Xuqiao Liu, Kai Yan, Jingdong Zhang
Background: 17β-estradiol (E2) is a steroid hormone that has the potential to disrupt the endocrine system, leading to adverse effects on both humans and ecosystems, even when present in low concentrations. The quantitative determination of E2 is of great practical significance. Hypothesis: Electrochemical methods offer several advantages, including low cost, ease of operation, and potential for miniaturization
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Study on the Chemical Composition of the Mainstream Cherry-red Tobacco Smoke Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-29 Yong Li, Tao Pang, Yihan Zhang, Junli Shi, Zhongbang Song, Zhaoli Xu
Introduction: Cherry-red tobacco is a flue-cured variant that possesses a distinctive “sticky rice” flavor, which is highly valued by the tobacco industry. However, the value of cherryred tobacco is dubious due to the possible health risks associated with tobacco-specific nitrosamines (TSNAs). Objective: This study aimed to investigate the chemical origin of the “sticky rice” flavor and to assess the
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Quantification of Rutin, an Anti-glycating Drug, in Selected Euphorbia Species by Florescence Spectroscopy and Partial Least Squares Regression Analysis Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-28 Maroof Ali, Ajmal Khan, Syed Abdullah Gilani, Liaqat Ali, Rabia Maqsood, Amjad Hussain, Hamida Al Rabani, Najeeb Ur Rehman, Farah Jabeen, Fazal Mabood, Ahmed Al-Harrasi, Javid Hussain
Background: Rutin is a natural flavonol that showed excellent antiglycation activity with an IC50 value of 294.5 ± 1.5 μM. In the current study, three selected plant species of Euphorbia, i.e., Euphorbia helioscopia, Euphorbia larica, and Euphorbia wallichii, were analyzed for the quantification of rutin. Methods: The quantification was done through a newly developed method of Emission spectroscopy
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Green Synthesis Derived Novel Fe2O3/ZnO Nanocomposite for Efficient Photocatalytic Degradation of Methyl Orange Dye Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-23 Nimisha Jadon, Bhupinder Kour, Bilal Ahmad Bhat, Harendra K. Sharma
Introduction: An eco-friendly method was reported for the synthesis of ferric oxide nanoparticles (Fe2O3), zinc oxide nanoparticles (ZnO) and Fe2O3/ZnO nanocomposite using Mangifera indica plant leaf extract as a natural reducing agent. Methods: The synthesized nanomaterials were successfully characterized by X-ray diffraction, UVvisible spectrophotometer, Photoluminescence spectroscopy and Transmission
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Review on Phytoremediation: Toxic Heavy Metal Removal Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-22 Rajesh Nithyanandam, Moontarij Jahan Orvy, Rajavarsini Rajesh, Rupika Rajendran, Jyotsna SudhiMithran
Among the environmental contaminants in water, heavy metals and other pollutants are becoming a common occurrence. To solve this issue, the process of phytoremediation was utilized to clear up polluted media. Heavy metal and other pollution contamination of water is becoming more common, which has prompted a conversation that goes beyond heavy metals. These
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Identification and Limit of Detection of Benzene, Chlorobenzene, Benzoic Acid, Phthalic Acid, and Mellitic Acid in Water Solutions Using Excitation, Emission, and Single-band Synchronous Fluorescence Spectroscopy Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-09 Suresh Sunuwar, Carlos E. Manzanares
Introduction: This paper first introduces the use of computer-simulated single-band synchronous fluorescence (SF) obtained from experimental excitation and emission fluorescence spectra of a pure compound in solution. The simulation produces a single narrow band with a peak wavelength that identifies the compound. Method: The method is used to show single peak identification of benzene, chlorobenzene
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Mechanical Activation as a Stage of Coal Sample Preparation in the Analysis of Rare Earth Elements Content by Inductively Coupled Plasma Mass Spectrometry Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-09 Lidiya I. Yudina, Tatiana S. Skripkina, Svetlana S. Shatskaya
Background: Brown coals are recognized as promising sources of rare earth elements (REEs). Rare earths are present in both the mineral and organic parts of brown coal. Objectives: This study was conducted to investigate the influence of preliminary mechanical activation in the process of sample preparation prior to analyzing the concentrations of rare earth elements in brown coal samples of various
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Metal-organic Frameworks: Emerging Luminescent Sensors Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-09 Meman Sahu, Vanshika Sharma, Goutam Kumar Patra
Metal-organic frameworks (MOFs), a crystalline material, are a new type of inorganicorganic hybrid material. MOFs are of great interest to researchers in chemistry and material science due to their various chemical and physical properties, and features include their remarkable surface area, high porosity, flexibility, structural variety, flexibility, extreme porosity, a large surface area, augmented
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A Systematic Study of Pyracantha crenulata Phytoconstituents for their Anti-Diabetic Activity Using Computational Techniques Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-09 Girish Chandra Arya
Background: Diabetes mellitus is a significant medical condition with rising incidence and fatality rates. According to WHO, around 422 million individuals globally have diabetes, the majority of whom live in low and middle-income economies. Diabetes is entirely responsible for 1.5 million fatalities yearly. Researchers are concentrating on plant derivatives due to the higher toxicity of conventional
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HPLC Analysis of Vitamins C, E, Beta-carotene, and Some Flavonoids in Armenian Red Wines Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-09 Ani A. Grigoryan, Ani A. Hayrapetyan, Zhermen A. Azaryan, Siranush V. Harutyunyan, Aleksandr P. Yengoyan
Background: Oxidative damage to biological molecules is mainly caused by free radicals produced in the body. Natural antioxidants can prevent the resulting oxidative stress. For this purpose, particularly grapes and grape products, which contain vitamins and polyphenolic substances with high antioxidant activity, are used. Methods: In the present study, the content of vitamins C and E, beta-carotene
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Label-free Electrochemical Nanobiosensors Using Au-SPE for COVID-19 Detection: A Comparative Review of Different Biomarkers and Recognition Elements Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-09 Babak Mikaeeli Kangarshahi, Seyed Morteza Naghib
An immediate and precise diagnosis is required due to the COVID-19 outbreak. Labelfree electrochemical biosensors show promise as potentially valuable instruments for detecting COVID-19. These biosensors are distinguished by their lack of complexity, high speed, sensitivity, and relatively low cost. The precise COVID-19 biomarkers may be recognized without labeling or amplification by detecting the
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Method Development and Validation for Simultaneous Detection of Corticosteroids, Small Peptides, SARMs and Quaternary Ammonium Drugs in Camel Urine for Doping Control Applications Curr. Anal. Chem. (IF 1.8) Pub Date : 2024-01-05 Jahfar Nalakath, Rasik P.T., Praseen O.K., Shamil P., N. Selvapalam, E.R. Nagarajan
Background: Detection and identification of a wide range of drugs, including small peptides, corticosteroids, selective androgen receptor modulators (SARMs), and quaternary ammonium drugs (QADs), are imperative across several domains, particularly in anti-doping analysis, given the potential misuse of these substances in animal sports, there is an urgent demand for an allencompassing screening method
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New Green and High-throughput Microwell Spectrophotometric Method for Quality Control of Pharmaceutical Formulations of Selective Serotonin Reuptake Inhibitors via Microscale Formation of their N-Vinylamino-naphthoquinone Derivatives Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-12-28 Reem M. Abuhejail, Nourah Z. Alzoman, Ibrahim A. Darwish
Background: Selective serotonin reuptake inhibitors (SSRIs) are mostly prescribed for the treatment of depression. This study describes the microscale in-microwell formation of blue-colored N-vinylamino-naphthoquinone derivatives of SSRIs upon their reaction with 2,3-dichloro-1,4- naphthoquinone (DCNQ) and acetaldehyde. The reaction was subsequently utilized as a basis for the development of a new
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Colorimetric and Electrochemical Sensors for the Detection of Sarcosine, A Potential Biomarker for Prostate Cancer: A Review Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-12-12 Vaishnavi Venugopal Iyer, Rajapriya Rajendran, Stalin Selvaraj
Sarcosine is currently identified as a potential biomarker for prostate cancer. It is n-methyl derivative of glycine, which is naturally present in muscle and body tissues. Studies indicate that a delay in the treatment of prostate cancer is often due to its diagnosis not being possible at earlier stages. Also, plasma and urine samples with increased sarcosine concentration exhibit a higher probability
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A Bioinformatics Study of the Influenza H5N1 Virus that Infects Wild Fowl and Poultry and, Potentially, Humans Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-12-08 Carlos Polanco, Vladimir N. Uversky, Alberto Huberman, Enrique Hernandez-Lemus, Mireya Martínez-Garcia, Claudia Pimentel Hernández, Martha Rios Castro, Thomas Buhse, Gilberto Vargas Alarcon, Jorge Alberto Castañón González, Juan Luciano Díaz González, Mauricio Missael Sanchez Díaz, Erika Jeannette López Oliva, Francisco J. Roldan Gomez, Brayans Becerra Lun
Introduction: More than sixteen countries are infected with the highly pathogenic avian influenza A-H5N1 virus. As the virus circles the world, it has led to the slaughter of millions of poultry birds as well as the infection of farmed mink in Europe and among seals and grizzly bears on the Northern coast of America; some infected mammals exhibited neurological symptoms like disorientation and blindness
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Quantitative HPLC-based Metabolomics Approach for the Discrimination of Processed Rhizomes of Atractylodes Macrocephala Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-12-06 Cao Thanh Hai, Nguyen Thu Uyen, Do Hoang Giang, Nguyen Thi Thu Minh, Hoang Thuy Duong, Bui Thi Nhat Le, Nguyen Trung Thanh, Truong Ngoc Minh, Nguyen Tien Dat
Background: The current study presents a method for the simultaneous quantification of atractylenolide I, II, and III, together with syringin, syringaresinol-4-O-β-D-glucoside and caffeine in Atractylode macrocephala (AM) rhizomes. Contents of the metabolites, in combination with the metabolomics approach, were used to discriminate AM rhizomes, which were processed by different methods. Method: An
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Aluminum Oxide Nanoparticles from Aluminum Door and Window Factory Wastes for the Removal of Methyl Green Dye from Wastewater: A Comparative Study Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-12-06 Wrea Mohammed Ibrahim, Ibrahim Qadr Saeed, Hunar Yasin Muhammad, Hijran Sanaan Jabbar
Background: It has become increasingly important to use non-toxic nanomaterials for treating industrial wastewater that contains organic dyes, such as methyl green. Method: A sol-gel method was used to synthesize aluminum oxide nanoparticles from waste aluminum and investigate the physicochemical process involved in their removal from methyl green. Result: The synthesized adsorbent was characterized
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Fabrication of a Molecularly Imprinted Polymer Adsorbent for Pipette Tip Micro Solid-phase Extraction of Levofloxacin from Aqueous Samples Prior to its Spectrophotometric Determination Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-12-01 Sayyed Hossein Hashemi, Massoud Kaykhaii, Ahmad Jamali Keikha, Jasem Jangizahi
Aims: The main goal of this research was to find a simple, selective, sensitive and rapid protocol for the detection of traces of levofloxacin (Lev) in seawater, pills, urine, and human plasma samples by using a novel sorbent made of molecularly imprinted polymer (MIP) for its pipette-tip micro-solid phase extraction (PT-μSPE), followed by spectrophotometry. Parameters affecting the method were evaluated
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Dengue Fever Virus Envelope Glycoproteins Variability Characterized Bioinformatically Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-11-29 Carlos Polanco, Vladimir N. Uversky, Alberto Huberman, Enrique Hernandez-Lemus, Martha Rios Castro, Erika Jeannette López Oliva, Mireya Martínez-Garcia, Thomas Buhse, Francisco J. Roldan Gomez, Gilberto Vargas-Alarcon, Cecilia Zazueta, Claudia Pimentel-Hernández
Background: The infection caused by the dengue fever virus is a severe threat to public health on a global scale; nevertheless, there is currently no effective medical treatment or vaccine available to prevent or treat the condition. Objective: To better understand the physicochemical regularities of these proteins, it is necessary to carry out a computational multiparametric study of the amino acid
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Molecularly Imprinted Electrochemical Sensor Based on Reduced Graphene Oxide-Gold Nanoparticles-Poly(p-aminobenzoic Acid) Nanocomposites for the Determination of Sunset Yellow Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-11-10 Youyuan Peng, Zhuojialu Li
Background: In this work, the reduced graphene oxide decorated with gold nanoparticles (Au/rGO) had been synthesized on glass carbon electrode (GCE) using a simple one-step electrochemical method. The molecularly imprinted poly(p-aminobenzoic acid) (PABA) film was prepared for the analysis of sunset yellow (SY) on Au/rGO/GCE by electropolymerization of p-aminobenzoic acid (pABA) and SY. Methods: Methods
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Label-free and Colorimetric Sensitive Detection of SNPs Based on Catalytic Beacon and RNase Cleavage Reaction Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-11-07 Zhaojiang Yu, Chunxue Zhao
Background: Single nucleotide polymorphisms (SNPs) are important hallmarks in various pathological activities, especially genetic and inherited diseases, and detecting them with accuracy, high throughput and low cost becomes increasingly necessary. Methods: Methods: Herein, we have developed a new label-free and sensitive detection method for SNPs assay. Due to its favorable traits, the method presents
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Nanotechnology-based Assays for the Detection of Cancer through Sputum Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-11-07 Dilpreet Singh
Cancer remains a formidable global health challenge, underscoring the critical need for early and accurate diagnostic tools. In recent years, nanotechnology has emerged as a promising frontier in cancer detection, offering innovative approaches to enhance sensitivity, specificity, and convenience in diagnostics. This comprehensive review delves into the intersection of nanotechnology and sputum-based
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Study on Separation Mechanism of Ephedrine and Pseudoephedrine in Borax Buffer by Capillary Electrophoresis Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-11-07 Jinqiu Xu, Yinhua Gong, Rongrong Huang, Liangliang Cai, Xiaofei Ma
Background: In borax buffer, ephedrine (EPH) and pseudoephedrine (PSE) can be well separated (Rs>10) in capillary electrophoresis (CE) without adding any other compounds, but the specific mechanism remains unclear. Methods: Titration analysis, nuclear magnetic resonance analysis, mass spectrum analysis and molecular modeling were used to investigate the separation mechanism. Results: Tetrahydroxy borate
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An Improved Amperometric D-amino Acid Biosensor Based on Immobilization of D-Amino Acid Oxidase on Nanocomposite of Chitosan/Fe3O4NPs/ cMWCNT/GC Electrode Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-11-03 Chandra Shekhar Pundir, Suman Lata, Bhawna Batra, Jyoti Ahlawat
Objective: An improved amperometric D aminoacid (DAA) biosensor was fabricated by immobilizing covalently, D-amino acid oxidase (DAAO) onto nanocomposite of chitosan (CHIT)/ iron oxide nanoparticles (Fe3O4)/ carboxylated multiwalled carbon nanotubes (cMWCNT)/ electrodeposited onto glassy carbon (GC) electrode. Methods: The iron oxide nanoparticles (Fe3O4) were prepared and characterized by UV spectroscopy
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A Novel Fluorescent Aptasensor Based on Mesoporous Silica Nanoparticles for Selective and Sensitive Detection of Saxitoxin in Shellfish Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-10-31 Najeeb Ullah, Beenish Noureen, Qurat ul ain Zahra, Tariq Aziz, Somia Shehzadi, Mohammad Y. Alfaifif, Serag Eldin I. Elbehairif, Khalid Hussain Thebo, Asmat Ullah, Haroon Iqbal
Background: Saxitoxin (STX) stands as one of the most potent marine biotoxins, exhibiting high lethality. Despite its severity, current treatments remain ineffective, and existing detection techniques are limited due to ethical concerns and technical constraints. Methods: Herein, an innovative approach was constructed for STX detection, utilizing mesoporous silica nanoparticles (MSN) as a foundation
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Characterization of a High-performance PCF-SPR Sensor for Biomedical Applications Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-10-27 Himansu Shekhar Pradhan
Background: Surface plasmon resonance (SPR) based fibre optic sensors are becoming increasingly popular in biomedical applications. However, the sensor performance is degraded because of low sensitivity with inadequate detection accuracy and figure of merit. Objectives: The first objective of this study is to design a D-shaped photonic crystal fibre (PCF) using COMSOL multiphysics. The second objective
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One-step Nonenzymatic Electrochemical Sensor for the Detection of Sarcosine Using Nanozyme Glutathione Copper Complex Curr. Anal. Chem. (IF 1.8) Pub Date : 2023-10-27 Janani Udayakumar, Stalin Selvaraj
Background: The present study aims to develop the use of glutathione copper complex for the detection of sarcosine, a marker for prostate cancer. The glutathione-copper complex was successfully synthesized at room temperature and characterized using FTIR, UV, and Scanning Electron Micrograph. Methods: The structure of the glutathione copper complex was found to be a 1:2 Metal: Ligand ratio. The cyclic