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Rice crop residue management by the microbial consortium for rapid decomposition of straw 3 Biotech (IF 2.8) Pub Date : 2024-04-25 Kunvar Gyanendra Kumar, Raja Husain, Anurag Mishra, Nitin Vikram, Devendra Kumar Dwivedi, Saurabh Pandey, Ashutosh Singh
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Functional study of two ER localized sterol C-14 reductases in Aspergillus oryzae 3 Biotech (IF 2.8) Pub Date : 2024-04-25 Yitong Shang, Qi Jin, Ganghua Li, Huanhuan Yan, Mingquan Yu, Zhihong Hu
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Structure-based virtual screening of mangiferin derivatives with antidiabetic action: a molecular docking and dynamics study and MPO-based drug-likeness approach 3 Biotech (IF 2.8) Pub Date : 2024-04-23 Francisco Flávio da Silva Lopes, Francisco Nithael Melo Lúcio, Matheus Nunes da Rocha, Victor Moreira de Oliveira, Caio Henrique Alexandre Roberto, Márcia Machado Marinho, Emmanuel Silva Marinho, Selene Maia de Morais
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Exploring the therapeutic effect of Pen Yan Kang Fu Decoction on SPID rats based on LIF/JAK2/STAT3 signaling pathway 3 Biotech (IF 2.8) Pub Date : 2024-04-23 Xiaoli Ji, Quan Hu, Chengcheng Yang, Li Huang, Yefang Huang, Linwen Deng, Xiaoqing Song, Yongqing Zhang, Yan Wang
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Delineating the role of host plants in regulating the water and salinity stress induced changes in sandalwood roots 3 Biotech (IF 2.8) Pub Date : 2024-04-22 Aarju Sharma, Kamlesh Verma, Ashwani Kumar, Sulekha Rani, Kajal Chauhan, Bindu Battan, Raj Kumar
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Concurrent effect of drought and heat stress in rice (Oryza sativa L.): physio-biochemical and molecular approach 3 Biotech (IF 2.8) Pub Date : 2024-04-19 Kongkong Mondal, Rup Kumar Kar, Abhra Chakraborty, Narottam Dey
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Isolation, screening and characterization of efficient cellulose-degrading fungal and bacterial strains and preparation of their consortium under in vitro studies 3 Biotech (IF 2.8) Pub Date : 2024-04-19 Deblina Roy, Sunil Kumar Gunri, Kamal Krishna Pal
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Microalgae for freshwater arsenic bioremediation: examining cellular toxicity, bioconcentration factor and eluding an alternative arsenic detoxification pathway 3 Biotech (IF 2.8) Pub Date : 2024-04-10 Wenn Wenn Tang, Su Chern Foo
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Wastewater treatment from a science faculty during the COVID-19 pandemic by using ammonium-oxidising and heterotrophic bacteria 3 Biotech (IF 2.8) Pub Date : 2024-04-09 Lucas D. Pedroza-Camacho, Paula A. Ospina-Sánchez, Felipe A. Romero-Perdomo, Nury G. Infante-González, Diana M. Paredes-Céspedes, Balkys Quevedo-Hidalgo, Viviana Gutiérrez-Romero, Claudia M. Rivera-Hoyos, Aura M. Pedroza-Rodríguez
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Identification of chemoresistance associated key genes-miRNAs-TFs in docetaxel resistant breast cancer by bioinformatics analysis 3 Biotech (IF 2.8) Pub Date : 2024-04-06 Baddipadige Raju, Gera Narendra, Himanshu Verma, Om Silakari
The present study aimed to identify the differentially expressed genes (DEGs) and enriched pathways in docetaxel (DTX) resistant breast cancer cell lines by bioinformatics analysis. The microarray dataset GSE28784 was obtained from gene expression omnibus (GEO) database. The differentially expressed genes (DEGs), gene ontology (GO), and Kyoto Encyclopedia of gene and genome (KEGG) pathway analyses
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Exploring the antioxidant potential of endophytic fungi: a review on methods for extraction and quantification of total antioxidant capacity (TAC) 3 Biotech (IF 2.8) Pub Date : 2024-04-05 Rita Onyekachukwu Asomadu, Timothy Prince Chidike Ezeorba, Tobechukwu Christian Ezike, Jude Obiorah Uzoechina
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Mucuna laticifera: unprecedented L-dopa content and its role in neurodegenerative and inflammatory conditions 3 Biotech (IF 2.8) Pub Date : 2024-04-04 Viresh Thamke, Suresh Suryawanshi, Chetan Aware, Pratibha Mali, Balkrishna Shinde, Devashree Patil, Manali Rane, Ashvini Chaudhari, Savita Tapase, Jyoti Jadhav
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LncRNA MRPL39 inhibits cell proliferation and migration by regulating miR-130/TSC1 axis in non-small cell lung cancer 3 Biotech (IF 2.8) Pub Date : 2024-04-02
Abstract Currently, the effect of miR-130 on non-small cell lung cancer (NSCLC) remains controversial. In this study, the expression of miR-130 and lncRNA MRPL39 in tumor and non-tumor tissues of NSCLC patients was examined using real-time PCR (RT-PCR) and correlated with the prognosis of NSCLC. The phenotypic effects of miR-130 and MRPL39 on proliferation and migration of NSCLC cell line A549 cells
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Investigation of the cellular and molecular effects of dehydrozingerone formulation on various days of diabetic wound repair 3 Biotech (IF 2.8) Pub Date : 2024-04-01
Abstract Cases of diabetes are significantly increasing year by year, attracting the attention of medical professionals and researchers to focus on diabetes and its underlying complications. One among such are diabetic wounds which are difficult to heal, creating severe implications in the day-to-day chores of not only patients, but also family members. Dehydrozingerone (DHZ) is known to possess various effects like
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Comparative studies on the cultivation, yield, and nutritive value of an edible mushroom, Pleurotus tuber-regium (Rumph. ex Fr.) Singer, grown under different agro waste substrates 3 Biotech (IF 2.8) Pub Date : 2024-03-30
Abstract In the present study, Pleurotus tuber-regium (Rumph. ex Fr.) Singer collected from Keeriparai forest of Kanyakumari district, South India was cultivated using environmentally benign, low-cost agricultural waste residues (paddy straw, sugarcane bagasse, rice husk, and sawdust) as growth substrates. The main goal of this study was to assess the cultivation, yield, and nutritional value of P
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Detection of selective sweep in European wild sheep breeds 3 Biotech (IF 2.8) Pub Date : 2024-03-28 Masoud Alipanah, Seyed Mostafa Mazloom, Faezeh Gharari
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Ischemic preconditioning modulates the DNA methylation process of the rat heart to provide tolerance to withstand ischemia reperfusion injury and its associated mitochondrial dysfunction 3 Biotech (IF 2.8) Pub Date : 2024-03-26 Sri Rahavi Boovarahan, Gino A. Kurian
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Chloroplast transformation in new cultivars of tomato through particle bombardment 3 Biotech (IF 2.8) Pub Date : 2024-03-25
Abstract A protocol has been established for genetic transformation of the chloroplasts in two new cultivars of tomato (Solanum lycopersicum L.) grown in India and Australia: Pusa Ruby and Yellow Currant. Tomato cv. Green Pineapple was also used as a control that has previously been used for establishing chloroplast transformation by other researchers. Selected tomato cultivars were finalized from
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Optimization of newly isolated Bacillus cereus α-amylase production using orange peels and crab shells and application in wastewater treatment 3 Biotech (IF 2.8) Pub Date : 2024-03-22 Bouthaina Ben Hadj Hmida, Sameh Ben Mabrouk, Ahmed Fendri, Aïda Hmida-Sayari, Adel Sayari
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Differentiation of placenta-derived MSCs cultured in human platelet lysate: a xenofree supplement 3 Biotech (IF 2.8) Pub Date : 2024-03-22 Merlin Sobia Poomani, Rathika Regurajan, Ramachandran Perumal, Aravindhakshan Ramachandran, Iyyadurai Mariappan, Krishnaveni Muthan, Venkatesh Subramanian
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Engineered E. coli for D-pantothenic acid production with an acetolactate isomeroreductase mutant 3 Biotech (IF 2.8) Pub Date : 2024-03-22
Abstract D-Pantothenic acid, as a momentous vitamin, is extensively applied to feed, medicine, cosmetics and other fields. However, there are still limitations to produce D-pantothenic acid by microbial fermentation at present. In this paper, we constructed a recombinant strain for D-pantothenic acid production by blocking the organic acid pathway, boosting pyruvate biosynthesis, relieving feedback
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Detection of typical indigenous gut bacteria related to kanpyo Lagenaria siceraria var. hispida powder in murine caecum and human faecal cultures 3 Biotech (IF 2.8) Pub Date : 2024-03-22 Mahiro Yamamoto, Hikaru Ogura, Takashi Kuda, Yumeng Xia, Ayaka Nakamura, Hajime Takahashi, Junji Inoue, Shu Takayanagi
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Rapid induction of dopaminergic neuron-like cells from human fibroblasts by autophagy activation with only 2-small molecules 3 Biotech (IF 2.8) Pub Date : 2024-03-20 Natchadaporn Sorraksa, Palakorn Kaokaen, Phongsakorn Kunhorm, Nudjanad Heebkaew, Wilasinee Promjantuek, Parinya Noisa
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Comparative genome-wide analysis of novel Streptomyces isolates RC1831 and RC1832: deciphering the role of functional carbohydrate (CAZy) active genes including chitinase for production of chitosan 3 Biotech (IF 2.8) Pub Date : 2024-03-20 Suchismita Nivedita, Subhransu Sekhar Behera, Himadri Tanaya Behera, Sudhansu Kumar Gouda, Ananta Narayana Panda, Lopamudra Ray
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Genome-wide identification and comparative analysis of YABBY transcription factors in oil tea and tea tree 3 Biotech (IF 2.8) Pub Date : 2024-03-19 Xiaoqin Zhang, Xianfeng Yang, Qinqin Zhang, Jialun Wang, Tingting Zeng, Yanan Xi, Qiang Shen
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Therapeutic proteins: developments, progress, challenges, and future perspectives 3 Biotech (IF 2.8) Pub Date : 2024-03-18 Vimal Kumar, Arti Barwal, Nitin Sharma, Danish Shafi Mir, Pradeep Kumar, Vikas Kumar
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A review on pharmacological studies of natural flavanone: pinobanksin 3 Biotech (IF 2.8) Pub Date : 2024-03-13 Brindha Elangovan
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Isolation and characterization of novel bioplasticizers from rose (Rosa damascena Mill.) petals and its suitability investigation for poly (butylene adipate-co-terephthalate) biofilm applications 3 Biotech (IF 2.8) Pub Date : 2024-03-12 Naushad Edayadulla, Divya Divakaran, Shanmuga Sundari Chandraraj, Indran Suyambulingam, Elammaran Jayamani, M. R. Sanjay, Suchart Siengchin
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Draft genome sequence of 'Candidatus Phytoplasma asteris,’ strain SW86 associated with sandal spike disease (SSD) 3 Biotech (IF 2.8) Pub Date : 2024-03-11 Kiran Kirdat, Bhavesh Tiwarekar, K. N. Manjula, S. Padma, Shivaji Sathe, R. Sundararaj, Amit Yadav
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Ab initio modeling of human IRS1 protein to find novel target to dock with drug MH to mitigate T2DM diabetes by insulin signaling 3 Biotech (IF 2.8) Pub Date : 2024-03-11 Ritika Kumari Singh, Avinash Kumar Chaurasiya, Arvind Kumar
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Isolation and molecular characterization of multidrug‑resistant Escherichia coli from chicken meat 3 Biotech (IF 2.8) Pub Date : 2024-03-10 Anugya Jaiswal, Aquib Khan, Akanksha Yogi, Sweta Singh, Arun Kumar Pal, Ramendra Soni, Pooja Tripathi, Jonathan A. Lal, Vijay Tripathi
Antibiotics in animal farms play a significant role in the proliferation and spread of antibiotic-resistant genes (ARGs) and antibiotic-resistant bacteria (ARB). The dissemination of antibiotic resistance from animal facilities to the nearby environment has become an emerging concern. The present study was focused on the isolation and molecular identification of Escherichia coli (E. coli) isolates
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An insight into the diagnostic, prognostic, and taxanes resistance of double zinc finger and homeodomain factor’s expression in naïve prostate cancer 3 Biotech (IF 2.8) Pub Date : 2024-03-10
Abstract Currently, clinical biomarkers are urgently needed to improve patient management to guide personal therapy for cancer. In this study, we investigate the deregulation of Zeb-1 in prostate cancer (PC) Tunisian patients. Expression patterns of the Zeb-1 were investigated in prostate adenocarcinoma and benign prostate biopsies using quantitative real-time reverse transcription-polymerase chain
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Characterizations of Ganoderma species causing basal stem rot disease in coconut tree 3 Biotech (IF 2.8) Pub Date : 2024-03-08 Umesh Sajjan, Manjunath Hubballi, Abhay K. Pandey, V. Devappa, H. P. Maheswarappa
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Anti-listerial peptides from a marine Bacillus velezensis FTL7: production optimization, characterizations and molecular docking studies 3 Biotech (IF 2.8) Pub Date : 2024-03-08
Abstract Antimicrobial peptides (AMPs) with potent anti-listerial activity were characterized from a novel marine Bacillus velezensis FTL7. A Box-Behnken statistical experimental design was used to study the combined impact of culture conditions on the production of AMPs by B. velezensis FTL7. The conditions optimized by statistical experimental design were 34.5 °C incubation temperature, 23 h incubation
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Mechanism of salt tolerance in the endangered semi-mangrove plant Barringtonia racemosa: anatomical structure and photosynthetic and fluorescence characteristics 3 Biotech (IF 2.8) Pub Date : 2024-03-08 Ju Hu, Xu Deng, Caihong Bai, Lin Li, Xiuling Yang, Chunxiao Lan, Haiyan Zhong, Xiaohui Tan, Fang Liang
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Intestinal microbial diversity of swines fed with different sources of lithium 3 Biotech (IF 2.8) Pub Date : 2024-03-06
Abstract A drug that is widely used in the treatment of psychiatric disorder is lithium (Li) salts. The people who make therapeutic use of this drug develop a series of side effects. Through metataxonomic data, this study assessed the impacts of lithium, as Li carbonate or Li-enriched mushrooms, on the microbial composition of the ileum, colon, and feces of piglets. Employing Bray–Curtis metric, no
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Protective effect of Pterospermum rubiginosum bark extract on bone mineral density and bone remodelling in estrogen deficient ovariectomized Sprague–Dawley (SD) rats 3 Biotech (IF 2.8) Pub Date : 2024-03-06
Abstract Osteoporosis is a common metabolic old age disorder characterised by low bone mass content (BMC) and mineral density (BMD) with micro-architectural deterioration of the extracellular matrix, further increasing bone fragility risk. Several traditional remedies, including plant extracts and herbal formulations, are used worldwide by local healers to improve the overall bone health and metabolism
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Preventive effect of Cleome spinosa against cucumber Fusarium wilt and improvement on cucumber growth and physiology 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Xingzhe Zhang, Xianghai Meng, Xiaodan Jiao, Rina Sa, Zhen Wang, Jiwen Li, Baicheng Wang, Dong Liu, Bing Yang, Chunlei Zou, Yanju Zhang
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In silico investigation of potential phytoconstituents against ligand- and voltage-gated ion channels as antiepileptic agents 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Punam Salaria, N. N. Subrahmanyeswara Rao, Tejas M. Dhameliya, M. Amarendar Reddy
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Diversity and functional characteristics of culturable bacterial endosymbionts from cassava whitefly biotype Asia II-5, Bemisia tabaci 3 Biotech (IF 2.8) Pub Date : 2024-03-05
Abstract Whitefly Bemisia tabaci, a carrier of cassava mosaic disease (CMD), poses a significant threat to cassava crops. Investigating culturable bacteria and their impact on whiteflies is crucial due to their vital role in whitefly fitness and survival. The whitefly biotype associated with cassava and transmitting CMD in India has been identified as Asia II 5 through partial mitochondrial cytochrome
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Heat shock protein paradigms in cancer progression: future therapeutic perspectives 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Y. Mohammed Tausif, Dithu Thekkekkara, Thummuru Ekshita Sai, Vaishnavi Jahagirdar, H. R. Arjun, S. K. Meheronnisha, Amrita Babu, Aniruddha Banerjee
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Evaluation of immunomodulatory (humoral as well as cell-mediated) and cytokines (TNF-α & IL-10) regulating potential of Neolamarckia cadamba fruit extract in Wistar albino rats 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Tarubala Sharma, Vishal Khandelwal
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Revisiting microbial exopolysaccharides: a biocompatible and sustainable polymeric material for multifaceted biomedical applications 3 Biotech (IF 2.8) Pub Date : 2024-03-04 Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini, Sudarshan Singh, Bhupendra Gopalbhai Prajapati
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Biological properties of caffeine, (+)-catechin, and theobromine: an in silico study 3 Biotech (IF 2.8) Pub Date : 2024-03-03 Nara Saraiva Dutra, Camila Medianeira da Silva D’Ávila, Thayline Correia da Silva, Tallys de Oliveira Mendes, Isadora Cassel Livinalli, Ana Clara Zanini Bertoncelli, Fernanda Krapf Saccol, Francine Carla Cadoná
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Optimized decolorization of two poly azo dyes Sirius Red and Sirius Blue using laccase-mediator system 3 Biotech (IF 2.8) Pub Date : 2024-03-01 Jihen Benali, Imen Ben Atitallah, Bouthaina Ghariani, Tahar Mechichi, Bilel Hadrich, Héla Zouari-Mechichi
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Antioxidant polysaccharide-enriched fractions obtained from olive leaves by ultrasound-assisted extraction with α-amylase inhibition, and antiproliferative activities 3 Biotech (IF 2.8) Pub Date : 2024-02-27 Rania Elayeb, Alejandra Bermúdez-Oria, Houda Lazreg Aref, Hatem Majdoub, Christos Ritzoulis, Alberto Mannu, Didier Le Cerf, Massimo Carraro, Sami Achour, Juan Fernández-Bolaños, Maher Trigui
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Microbial community dynamics and functional potentials in the conversion of oil palm wastes into biomethane 3 Biotech (IF 2.8) Pub Date : 2024-02-26 Hui Jing Ng, Kian Mau Goh, Adibah Yahya, Mohd Firdaus Abdul-Wahab
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Exploring genetic divergence and marker-trait associations for leaffolder Cnaphalocrocis medinalis (Guenee) resistance in rice landraces 3 Biotech (IF 2.8) Pub Date : 2024-02-25 Anjan Kumar Nayak, Prasanthi Golive, Arundhati Sasmal, B. N. Devanna, C. Anilkumar, Arup Kumar Mukherjee, Soumya Shephalika Dash, Shyamaranjan Das Mohapatra, Hatanath Subudhi
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Performance of Metarhizium rileyi Nm017: nutritional supplementation to improve production and quality conidia 3 Biotech (IF 2.8) Pub Date : 2024-02-24 Cindy Mejía, Jaime Rocha, Johanna Sanabria, Martha Isabel Gómez-Álvarez, Ginna Quiroga-Cubides
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Adenine’s impact on mice’s gut and kidney varies with the dosage administered and relates to intestinal microorganisms and enzyme activities 3 Biotech (IF 2.8) Pub Date : 2024-02-22 Mengsi Zhou, Xiaoya Li, Jin Liu, Yi Wu, Zhoujin Tan, Na Deng
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Autophagy: a necessary evil in cancer and inflammation 3 Biotech (IF 2.8) Pub Date : 2024-02-20
Abstract Autophagy, a highly regulated cellular process, assumes a dual role in the context of cancer. On the one hand, it functions as a crucial homeostatic pathway, responsible for degrading malfunctioning molecules and organelles, thereby maintaining cellular health. On the other hand, its involvement in cancer development and regression is multifaceted, contingent upon a myriad of factors. This
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Genome-wide analysis of cellulose synthase gene superfamily in Tectona grandis L.f. 3 Biotech (IF 2.8) Pub Date : 2024-02-19 Swathi Balakrishnan, Reshma Bhasker, Yasodha Ramasamy, Suma Arun Dev
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Enhancing (2S)-naringenin production in Saccharomyces cerevisiae by high-throughput screening method based on ARTP mutagenesis 3 Biotech (IF 2.8) Pub Date : 2024-02-18 Qian Gao, Song Gao, Weizhu Zeng, Jianghua Li, Jingwen Zhou
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Optimization of fungal chitosan production from Cunninghamella echinulata using statistical designs 3 Biotech (IF 2.8) Pub Date : 2024-02-18 Bhoomika M. Karamchandani, Priya A. Maurya, Manik Awale, Sunil G. Dalvi, Ibrahim M. Banat, Surekha K. Satpute
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circ_UTRN inhibits ferroptosis of ARJ21 cells to attenuate acute pancreatitis progression by regulating the miR-760-3p/FOXO1/GPX4 axis 3 Biotech (IF 2.8) Pub Date : 2024-02-18 Lanlan Wei, Bowen Li, Jing Long, Yanping Fu, Bin Feng
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Discovery of novel anticancer flavonoids as potential HDAC2 inhibitors: virtual screening approach based on molecular docking, DFT and molecular dynamics simulations studies 3 Biotech (IF 2.8) Pub Date : 2024-02-18
Abstract Virtual screening of a library of 329 flavonoids obtained from the NPACT database was performed to find out potential novel HDAC2 inhibitors. Eleven out of 329 selected flavonoids were screened based on molecular docking studies, as they have higher binding affinities than the standard drugs vorinostat and panobinostat. All screened compounds occupying the catalytic site of HDAC2 showed important
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Genome-wide runs of homozygosity signatures in diverse Indian goat breeds 3 Biotech (IF 2.8) Pub Date : 2024-02-17 Dibyasha Kar, Indrajit Ganguly, Sanjeev Singh, Avnish Kumar Bhatia, S. P. Dixit
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Phytol from Scoparia dulcis prevents NF-κB-mediated inflammatory responses during macrophage polarization 3 Biotech (IF 2.8) Pub Date : 2024-02-17 Parimalanandhini Duraisamy, Annapoorani Angusamy, Sangeetha Ravi, Mahalakshmi Krishnan, Livya Catherene Martin, Beulaja Manikandan, Janarthanan Sundaram, Manikandan Ramar
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Diversity of soil fungi from sacred groves of Kerala, India revealed by comparative metagenomics analysis using illumina sequencing 3 Biotech (IF 2.8) Pub Date : 2024-02-16
Abstract The diversity, composition, and abundance of soil fungi from three sacred groves in Kerala, namely Iringole kavu of Ernakulam District, Kollakal Thapovanam of Alappuzha District, and Poyilkavu of Kozhikode District were analysed using Metagenomics analysis and Illumina sequencing. A total of 30,584, 78,323, and 55,640 reads were obtained from these groves, respectively. Ascomycota constitutes
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Cardiovascular risk factors and carotid intima-media thickness with neurocognitive dysfunction in people living with HIV on stable combination anti-retroviral therapy 3 Biotech (IF 2.8) Pub Date : 2024-02-15
Abstract The goal of this clinical research was to determine the relationship between carotid intima-media thickness (cIMT), cardiovascular risk factors, and neuro-cognitive function in people living with HIV (PLHIV) and were on stable combination anti-retroviral therapy (cART). This is a cross-sectional study performed at a single center, including 149 patients who visited the anti-retroviral therapy