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TP53INP2 knockdown inhibits inflammatory response and apoptosis after spinal cord injury Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Penghao Sun, Jinchuan Chen, Rujie Qin
BackgroundSpinal cord injury (SCI) is a traumatic neurological disorder with limited therapeutic options. Tumor protein p53‐inducible nuclear protein 2 (TP53INP2) is involved in the occurrence and development of various diseases, and it may play a role during SCI via affecting inflammation and neuronal apoptosis. This study investigated the associated roles and mechanisms of TP53INP2 in SCI.MethodsMouse
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Study on the mechanism of miRNAs on liver injury in the condition of Protoscocephalus alveolarus transhepatic portal vein infection Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Yazhou Zhu, Ming Li, Zihua Li, Jiahui Song, Wei Zhao
ObjectiveTo explore the role of miRNA in liver damage caused by Echinococcus multilocularis infection.MethodsSix female C57BL mice were randomly divided into two groups, the control group and the infection group. Mice in the control group were injected with 100 μL PBS through the hepatic portal vein, and mice in the infection group were infected with E. multilocularis via the hepatic portal vein to
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Serum vitamins and homocysteine levels in autoimmune liver disease: A systematic review and meta‐analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Jiahuan Li, Shan Tian, Bai Ci, Yuwen Xi, Xiaoling Deng
ObjectiveVitamins and homocysteine (Hcy) are involved in liver metabolism and related to the pathogenesis of autoimmune liver disease (AILD), but consensus is lacking. This study aims to systematically summarize relevant evidence to clarify the association of serum vitamins and Hcy levels with AILD.MethodsThe English and Chinese literature was searched until August 29, 2023. Studies were included if
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Comparison of effectiveness and safety of molnupiravir versus sotrovimab for COVID‐19: A systematic review and meta‐analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Bahman Amani, Behnam Amani
Background and AimThis systematic review and meta‐analysis aimed to compare the effectiveness and safety of molnupiravir and sotrovimab in the treatment of patients with coronavirus disease 2019 (COVID‐19).MethodsCochrane Library, Web of Science, PubMed, medRxiv, and Google Scholar were systematically searched to identify relevant evidence up to December 2023. The risk of bias was assessed using the
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Association of IL‐33 in modeling type‐2 airway inflammation and pulmonary emphysema in mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Chika Miyaoka, Masato Watanabe, Keitaro Nakamoto, Yuki Yoshida, Aya Hirata, Jumpei Aso, Hiroki Nunokawa, Manabu Ishida, Koujiro Honda, Saori Takata, Takeshi Saraya, Haruyuki Ishii
We developed pulmonary emphysema and a type 2 airway inflammation overlap mouse model. The bronchoalveolar lavage (BAL) interleukin 13 (IL‐13), IL‐4, and IL‐5 levels in the overlap model were higher than in the pulmonary emphysema model and lower than in the type 2 airway inflammation model, but IL‐33 level in the lung was higher than in other models. IL‐33 and interferon‐γ (IFNγ) in lungs may control
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Natural killer cell subsets and their functional molecules in peripheral blood of the patients with breast cancer Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Reza Darvishvand, Somayeh Rezaeifard, Razie Kiani, Sedigheh Tahmasebi, Zahra Faghih, Nasrollah Erfani
BackgroundNatural killer (NK) cells, CD3− lymphocytes, are critical players in cancer immune surveillance. This study aimed to assess two types of CD3− NK cell classifications (subsets), that is, convectional subsets (based on CD56 and CD16 expression) and new subsets (based on CD56, CD27, and CD11b expression), and their functional molecules in the peripheral blood of patients with breast cancer (BC)
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Association between serum 25‐hydroxyvitamin D level and inflammatory markers in hemodialysis‐treated patients Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-23 Chunlei Luo, Xueyan Bian, Lingling Bao, Qingqing Xu, Chunyang Ji
ObjectiveTo investigate the relationship between serum 25‐hydroxyvitamin D (25(OH)D) level with novel inflammatory markers in hemodialysis‐treated patients.MethodsA total of 167 maintenance hemodialysis‐treated patients were enrolled in this cross‐sectional study. The patients were divided into vitamin D deficiency (a serum 25(OH)D level <20 ng/mL) and nondeficiency (a serum 25(OH)D level ≥20 ng/mL)
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Biomarker role of maternal soluble human leukocyte antigen G in pre‐eclampsia: A meta‐analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-19 Abhinav Bhattarai, Sangam Shah, Krishna Dahal, Raksha Neupane, Sangharsha Thapa, Niraj Neupane, Joshuan J. Barboza, Anisha Shrestha, Ranjit Sah, Vasso Apostolopoulos
IntroductionHuman leukocyte antigen‐G (HLA‐G) is a non‐classical class I HLA molecule shown to regulate the immunomodulation of maternal immune cells to prevent fetal tissue destruction. Low levels of freely circulating maternal soluble HLA‐G (sHLA‐G) have been observed in pre‐eclampsia, however, no pooled evidence exists. This meta‐analysis aimed to generate pooled findings on the association of sHLA‐G
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Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis‐associated acute kidney injury Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Yanyan Shao, Weihao Yu, Hailun Cai
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Association analysis between CD14 gene polymorphisms and peri‐implantitis susceptibility in a Chinese population Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Jie Li, Xiao Qiao, Jin Shang
ObjectiveThe goal of the study was to examine the genetic correlation of cluster of differentiation 14 (CD14) gene polymorphisms with peri‐implantitis (PI) predisposition in a Chinese Han population.MethodsIn the case‐control study, blood samples were collected from PI patients and healthy individuals (n = 120/group), who were admitted to the Affiliated Hospital of Yangzhou University from 2021 to
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Knowledge mapping and global trends of drug hypersensitivity from 2013 to 2023: A bibliometric analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Li Luo, Niannian Chen, Zhanpeng Li, Chunmei Zhao, Yiming Dong, Likai Wang, Xiaoqian Li, Wenchao Zhou, Yingna Li, Cairong Gao, Xiangjie Guo
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Intermittent hypoxic pretreatment exacerbates house dust mite‐induced asthma airway inflammation Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Hao Meng, Dongxue Zhang, Yifan Que, Peng Hu, Runsheng Wang, Yunfei Liao, Guogang Xu
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Adipose tissue IL‐18 production is independent of caspase‐1 and caspase‐11 Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Luis Román‐Domínguez, Jonathan Salazar‐León, Karla F. Meza‐Sosa, Leonor Pérez‐Martínez, Gustavo Pedraza‐Alva
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Monocyte HLA‐DR level on admission predicting in‐hospital mortality rate in exertional heatstroke: A 12‐year retrospective study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Fanfan Wang, Fanghe Gong, Xuezhi Shi, Jiale Yang, Jing Qian, Lulu Wan, Huasheng Tong
BackgroundExertional heatstroke (EHS), a fatal illness, pronounces multiple organ dysfunction syndrome (MODS) and high mortality rate. Currently, no ideal factor prognoses EHS. Decreased monocyte human leukocyte‐DR antigen (mHLA‐DR) has been observed in critically ill individuals, particularly in those with sepsis. While most research focus on the pro‐inflammatory response exploration in EHS, there
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Effects of oropharyngeal administration of own mother's milk on oral microbial colonization in very low birth weight infants fed by gastric tube: A randomized controlled trial Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-17 Jie Liu, Xiyang Zhang, Qian Zhao, Xiaohe Mu, Chuanzhong Yang, Yan Ning, Xiaoyun Xiong, Xiaoling Qin, Lilian Chen
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STAT activation in regulatory CD4+ T cells of patients with primary sclerosing cholangitis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-12 Leona Dold, Sandra Kalthoff, Leonie Frank, Taotao Zhou, Pia Esser, Philipp Lutz, Christian P. Strassburg, Ulrich Spengler, Bettina Langhans
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Shorter telomere length increases the risk of lymphocyte immunodeficiency: A Mendelian randomization study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-12 Bo Wang, Yongqiang Xiong, Ren Li, Jiewen Zhang, Shu Zhang
BackgroundFor a long time, the prevailing viewpoint suggests that shorter telomere contribute to chromosomal instability, which is a shared characteristic of both aging and cancer. The newest research presented that T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to some cancers. However, the relationship between genetically determined
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LncRNA MIR100HG affects the proliferation and metastasis of lung cancer cells through mediating the microRNA‐5590‐3p/DCBLD2 axis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-11 Shengping Min, Linxiang Zhang, Li Zhang, Fangfang Liu, Miao Liu
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The experimental study of mir‐99a‐5p negative regulation of TLR8 receptor mediated‐mediated innate immune response in rabbit knee cartilage injury Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-11 Jiebin Zhang, Ke Zheng, Yichao Wu, Shengting Zhang, Ao Guo, Cong Sui
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Correlation between inflammatory factors, autophagy protein levels, and infection in granulation tissue of diabetic foot ulcer Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Lijuan Deng, Gang Wang, Shang Ju
ObjectiveTo observe the expression of inflammatory factors and autophagy‐related proteins in granulation tissue of diabetic foot ulcer (DFU) patients and analyze their relationship with infection.MethodsThis is a retrospective cohort study. One hundred and fifty‐two patients with DFU in our hospital from July 2020 to March 2022 were selected as the DFU group, including 98 cases in infection stage group
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Construction and experimental validation of a novel ferroptosis‐related gene signature for myelodysplastic syndromes Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Yidong Zhu, Jun He, Rong Wei, Jun Liu
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LINC01686 affects LPS‐induced cytokine expression via the miR‐18a‐5p/A20/STAT1 axis in THP‐1 cells Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Jongwon Baek, Hyeung‐Seob Shin, Kyoungho Suk, Won‐Ha Lee
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The proportion of CD161 on CD56+ NK cells in peripheral circulation associates with clinical features and disease activity of primary Sjögren's syndrome Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Ping Zhao, Yanhong Yang, Saizhe Song, Wei Cheng, Cheng Peng, Xin Chang, Jian Wu, Cuiping Liu
ObjectivesThe purpose of this study was to examine the proportion of CD161 on CD56+ natural killer (NK) cells in peripheral blood of primary Sjögren's syndrome (pSS) and investigate its clinical relevance of pSS.MethodsThe proportion of CD56+ NK cells and CD161 on CD56+ NK cells was detected by flow cytometry in 31 pSS patients and 29 healthy controls (HCs). The correlations between the proportion
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CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF‐β1/Smad2/3 signaling in mouse viral myocarditis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Jing Wei, Dan‐feng Wang, Cong‐cong Cui, Jia‐jia Tan, Ming‐yu Peng, Hong‐xiang Lu
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Blood MALT1 expression could help predict treatment outcomes in psoriasis patients, especially in those receiving biologics Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Qiaoli Liu, Yanfeng Zhang, Bing Xu, Xiaobo Jin, Tao Yang, Leiqiang Fan
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Correlation of clinical, laboratory, and short‐term outcomes of immunocompromised and immunocompetent COVID‐19 patients with semi‐quantitative chest CT score findings: A case‐control study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Abdolkarim Haji Ghadery, Ladan Abbasian, Fatemeh Jafari, Niloofar Ayoobi Yazdi, Zahra Ahmadinejad
BackgroundAs the effects of immunosuppression are not still clear on COVID‐19 patients, we conducted this study to identify clinical and laboratory findings associated with pulmonary involvement in both immunocompromised and immunocompetent patients.MethodsA case‐control of 107 immunocompromised and 107 immunocompetent COVID‐19 patients matched for age and sex with either positive RT‐PCR or clinical‐radiological
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Coexistence of ankylosing spondylitis and Behçet's disease: Successful treatment with upadacitinib Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Krasimir Kraev, Petar Uchikov, Bozhidar Hristov, Maria Kraeva, Yordanka Basheva‐Kraeva, Stanislava Popova‐Belova, Milena Sandeva, Dzhevdet Chakarov, Snezhanka Dragusheva, Mariela Geneva‐Popova
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Analysis of network expression and immune infiltration of disulfidptosis‐related genes in chronic obstructive pulmonary disease Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Yanqun Liu, Tao Zhu, Juan Wang, Yan Cheng, Qiang Zeng, Zhangqiang You, Guangming Dai
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Effect of IL‐17 on pulmonary artery smooth muscle cells and connective tissue disease‐associated pulmonary arterial hypertension Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Tian‐Yan Shi, Xiao‐Hong Wen, Juan Meng, Yue‐Wu Lu
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Relationship of neutrophil/lymphocyte ratio with cerebral small vessel disease and its common imaging markers Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Jiangping Cai, Xiaoyi Zeng, Xiaojin Huang, Hansheng Dong, Junyi Liu, Jie Lin, Meirong Xie, Xiaolan Wei
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Clinical benefits of novel non‐nucleoside reverse transcriptase inhibitors: A prospective cohort study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Shujing Ma, Xiaoxin Xie, Yanhua Fu, Lin Gan, Xiaoyan Yang, Linghong Kong, Jun Li, Hai Long
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Nirmatrelvir and ritonavir combination against COVID‐19 caused by omicron BA.2.2 in the elderly: A single‐center large observational study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-04-05 Can Chen, Ranyi Li, Shuliang Xing, Lei Cao, Yue Qu, Qianzhou Lv, Xiaoyu Li, Zhangzhang Chen
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Case report: Systemic lupus erythematosus combined with myocardial hypertrophy Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-27 Shanshan Wang, Xinfeng Wei, Wenqing Yang, Dan Zhang
ObjectiveSystemic lupus erythematosus (SLE) is a multisystem‐involved, highly heterogeneous autoimmune disease with diverse clinical manifestations. We report an extremely rare case of SLE with severe diffuse myocardial hypertrophy.MethodsThe patientʼs echocardiography and cardiac magnetic resonance imaging (CMR) results indicated diffuse myocardial hypertrophy. After excluding coronary atherosclerosis
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Preventing breast milk HIV transmission using broadly neutralizing monoclonal antibodies: One size does not fit all Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-27 Philippe Van de Perre, Gabriella Scarlatti, Penny L. Moore, Jean‐Pierre Molès, Nicolas Nagot, Thorkild Tylleskär, Glenda Gray, Ameena Goga
Key messages Passive immunoprophylaxis with broadly neutralizing monoclonal antibodies (bNAbs) could be a game changer in the prevention of human immunodeficiency virus (HIV) acquisition. The prevailing view is that available resources should be focused on identifying a fixed combination of at least three bNAbs for universal use in therapeutic and preventive protocols, regardless of target populations
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Unveiling global research trends and hotspots on mitochondria in NAFLD from 2000 to 2023: A bibliometric analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-27 Jingqin Hu, Ze Chen, Yibing Zhou, Yinglun Li, Jing Liu, Yuqiang Mi, Li Wang, Feng Jiang, Ping Li
BackgroundNonalcoholic fatty liver disease (NAFLD) has garnered significant attention in the past decade as a prevalent chronic liver condition. Despite a growing body of evidence implicating mitochondria in NAFLD development, comprehensive bibliometric analyses within this research domain are scarce. This study aims to provide a thorough overview of the knowledge framework and key research areas related
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Exosomes secreted from induced pluripotent stem cell ameliorate the lipopolysaccharide induced neuroinflammatory response via lncRNA‐0949 Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-27 Lixiu Ma, Ce Xiao, Zhizhe Zhang, Yi‐an Zhan
PurposeTo study the effect of exosomes derived from the induced pluripotent stem cells (iPSCs) in the neuroinflammatory response of microglia caused by lipopolysaccharide (LPS) and reveal the potential underlying mechanism.MethodsA permanent microglia cell line HMO6 was activated by LPS. The features of exosomes were analyzed by nano flow cytometry, Western blot and transmission electron microscope
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Effects of increasing sensitizing doses of ovalbumin on airway hyperresponsiveness in asthmatic mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-27 Yan‐Jiao Chen, Yu Yuan, Lu Peng, Xin‐Yi Dong, Yu‐Dong Xu, Yu Wang, Yong‐Qing Yang
BackgroundThe dosage of ovalbumin (OVA) during the sensitization stage is considered a crucial factor in the development of airway hyperresponsiveness (AHR). However, the inconsistent dosages of sensitizing OVA used in current studies and the lack of research on their impact on AHR are notable limitations.MethodsWe examined the impact of increasing sensitizing doses of OVA in a murine asthma model
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Differential expression of serum TM, PAF, and CD62P in patients with autologous arteriovenous fistula and the correlation with vascular access function Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-27 Yan Jiang, Zongyang Liu, Liting Liu, Zhiqian Xiong, Yan Chen, Shuai Zhang, Chaojiang Su
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Investigating the association between the tissue expression of miRNA‐101, JAK2/STAT3 with TNF‐α, IL‐6, IL‐1β, and IL‐10 cytokines in the ulcerative colitis patients Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-22 Qazaleh Voshagh, Amir Anoshiravani, Amin Karimpour, Golnaz Goodarzi, Sadra Samavarchi Tehrani, Ozra Tabatabaei‐Malazy, Ghodratollah Panahi
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Association between helminth infection and allergic disorders among children in Batu, Ethiopia Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-22 Sosina Walelign, Mheret Tesfaye, Geremew Tasew, Kassu Desta, Aster Tsegaye, Bineyam Taye
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Effects of therapeutic hypercapnia on the expression and function of γδT cells in transplanted lungs in rats Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-20 Qing Xie, Jia Lu, XiaoGuang Cui
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Diagnostic value of neutrophil‐to‐lymphocyte and platelet‐to‐lymphocyte ratio to predict recurrent pregnancy loss and abortion; a systematic review and meta‐analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-20 Sedigheh Hantoushzadeh, Omid Kohandel Gargar, Kyana Jafarabady, Mohammad Moein Rezaei, Fatemeh Asadi, Nasim Eshraghi, Zahra Panahi, Saeedeh Shirdel, Masoumeh Mirzamoradi, Marjan Ghaemi
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Obesity correlates with the immunosuppressive ILC2s‐MDSCs axis in advanced breast cancer Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-19 Wei Liu, Bingyu Li, Dan Liu, Bing Zhao, Gang Sun, Jianbing Ding
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Pyroptosis and polarization of macrophages in septic acute lung injury induced by lipopolysaccharide in mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-19 Sijiang Zhou, Xia Yang, Kanglin Mo, Zong Ning
BackgroundPyroptosis and polarization are significant contributors to the onset and development of many diseases. At present, the relationship between pyroptosis and polarization in acute lung injury (ALI) caused by sepsis remains unclear.MethodsThe ALI model for sepsis was created in mice and categorized into the blank control, lipopolysaccharide (LPS) group, LPS + low‐dose Belnacasan group, LPS +
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COVID‐19 in patients with Down syndrome: A systematic review Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-19 Praveen N. K. Pitchan Velammal, Suryakumar Balasubramanian, Fathima Shehnaz Ayoobkhan, Gautham V. K. Mohan, Pearl Aggarwal, Ali A. Rabaan, Syed A. Khan, Farah Yasmin, Thoyaja Koritala, Salim R. Surani
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Sodium butyrate activates the KATP channels to regulate the mechanism of Parkinson's disease microglia model inflammation Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-19 Ye Xu, Laofu Wen, Yunyi Tang, Zhenqiang Zhao, Miaojing Xu, Tan Wang, Zhibin Chen
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Fortunellin ameliorates LPS‐induced acute lung injury, inflammation, and collagen deposition by restraining the TLR4/NF‐κB/NLRP3 pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-19 Danjuan Liu, Rongjie Guo, Bingbing Shi, Min Chen, Shuoyun Weng, Junting Weng
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Undaria pinnatifida ameliorates nasal inflammation by inhibiting eosinophil and mast cell activation and modulating the NF‐κB/MAPKs signaling pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-16 Zhen Nan Yu, Yan Jing Fan, Thi Van Nguyen, Chun Hua Piao, Byung‐Hoo Lee, So‐Young Lee, Hee Soon Shin, Chang Ho Song, Ok Hee Chai
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Anti‐inflammatory potential of remimazolam: A laboratory and clinical investigation Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-14 Shota Tsukimoto, Atsuhiro Kitaura, Hidetaka Kuroda, Uno Imaizumi, Fumihiko Yoshino, Ayaka Yoshida, Shinchi Nakao, Noriyuki Ohta, Yasuhumi Nakajima, Takuro Sanuki
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Hmgcs2 is the hub gene in diabetic cardiomyopathy and is negatively regulated by Hmgcs2, promoting high glucose‐induced cardiomyocyte injury Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-13 Ying Wang, Li‐Feng Ping, Fu‐Yan Bai, Xin‐Huan Zhang, Guang‐Hong Li
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Elevated level of circulating calprotectin correlates with severity and high mortality in patients with COVID‐19 Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-13 Haoran Zhang, Qingyu Zhang, Kun Liu, Zenong Yuan, Xiqiang Xu, Jun Dong
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Berberine: A natural modulator of immune cells in multiple sclerosis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-13 Esmaeil Yazdanpanah, Sepehr Dadfar, Alireza Shadab, Niloufar Orooji, MohammadHossein Nemati, Alireza Pazoki, Seyed‐Alireza Esmaeili, Rasoul Baharlou, Dariush Haghmorad
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Regulatory RNAs in immunosenescence Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-08 Atefe Ghamar Talepoor, Mehrnoosh Doroudchi
BackgroundImmunosenescence is a multifactorial stress response to different intrinsic and extrinsic insults that cause immune deterioration and is accompanied by genomic or epigenomic perturbations. It is now widely recognized that genes and proteins contributing in the process of immunosenescence are regulated by various noncoding (nc) RNAs, including microRNAs (miRNAs), long ncRNAs, and circular
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Dietary composition of adult eosinophilic esophagitis patients is related to disease severity Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-08 Simone R. B. M. Eussen, Sanne Wielders, Willemijn E. de Rooij, Marleen T. J. Van Ampting, Betty C. A. M. Van Esch, Jeanne H. M. de Vries, Albert J. Bredenoord, Berber Vlieg‐Boerstra
BackgroundIn addition to the elimination diet, dietary composition may influence disease severity in patients with eosinophilic esophagitis (EoE) through modulation of the immune response.AimTo explore the immunomodulatory role of nutrition before and during elimination diet in adult EoE patients.MethodsNutritional intake was assessed in 39 Dutch adult EoE patients participating in the Supplemental
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A multicenter study of severity and prognosis of symptomatic COVID‐19 in end‐stage renal disease and non‐dialysis patients in East of Iran Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-08 Tara Mohsenzadeh, Masood Ziaee, Hamid Salehiniya, Hossein Mohsenzadeh, Amin Mirsani, Vajehallah Raeesi
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Vitamin D improves autoimmune diseases by inhibiting Wnt signaling pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-28 Minshu Zou, Qiuju Song, Taiyong Yin, Hongtao Xu, Guoming Nie
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Comparison of the efficacy and safety of TAF, TDF, and LdT to prevent the transmission of hepatitis B in pregnant women: A retrospective study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-28 Shufang Pan, Ying Zhang, Yingfu Zeng, Chaoshuang Lin
ObjectiveTo compare the efficacy and safety of telbivudine (LdT), tenofovir alafenamide fumarate (TAF), and tenofovir disoproxil fumarate (TDF) for preventing hepatitis B transmission in immune‐tolerant pregnant women with HBV infection.MethodsWe conducted a retrospective cohort study involving women who had hepatitis B virus deoxyribonucleic acid (HBV DNA) ≥ 2 × 105 IU/mL and initiated LdT, TDF, or
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HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-28 Xiaofeng Zhu, Yue Dou, Yawen Lin, Gaoping Chu, Jing Wang, Lei Ma