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Genetics of Postsurgical Pain: Where Do We Go from Here? Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Carolina B Meloto
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Acid-Base Analysis in the Operating Room: A Bedside Stewart Approach. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 David A Story
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Electrical Impedance Tomography: Is It Ready to Measure Pulmonary Perfusion Distribution at the Bedside? Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Christian Putensen,Luciano Gattinoni,Steffen Leonhardt
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Alveolar Tipping Points in Changing Lungs Related to Positive End-expiratory Pressure. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Tilo Winkler,Marcelo B P Amato
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Embracing Labor Neuraxial Analgesia as a Tool to Reduce Health Inequities and Hemorrhage-related Maternal Morbidity. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Melissa E Bauer,Lindsay K Admon
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Healthcare Costs of New Functional Impairment in the Year after Noncardiac Surgery. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Julian F Daza,Harindra C Wijeysundera,Calvin Diep,Karim S Ladha,Brian H Cuthbertson,Duminda N Wijeysundera,
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Movement-evoked pain versus pain at rest in postsurgical clinical trials, and, in meta-analyses: An updated systematic review. Anesthesiology (IF 8.8) Pub Date : 2023-11-28 Ian Gilron,Nicholas Lao,Meg Carley,Daenis Camiré,Henrik Kehlet,Timothy J Brennan,Jason Erb
BACKGROUND Given the widespread recognition that postsurgical movement-evoked pain (MEP) is generally more intense, and more functionally relevant, than pain at rest (PAR), we conducted an update to a previous 2011 review to re-evaluate the assessment of PAR and MEP in more recent postsurgical analgesic clinical trials. METHODS We searched MEDLINE and Embase for postsurgical pain randomized controlled
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Intraoperative mechanical power and postoperative pulmonary complications in non-cardiothoracic elective surgery patients: a ten-year retrospective cohort-study. Anesthesiology (IF 8.8) Pub Date : 2023-11-28 Bertrand Elefterion,Cedric Cirenei,Eric Kipnis,Emeline Cailliau,Amélie Bruandet,Benoit Tavernier,Antoine Lamer,Gilles Lebuffe
BACKGROUND Postoperative Pulmonary Complications (PPC) is a major issue that impacts outcomes of surgical patients. Our hypothesis was that the intraoperative ventilation parameters are associated with occurrence of PPCs. METHODS We conducted a single-center retrospective cohort-study at the Lille University Hospital, France. We included 33701 adults undergoing non-cardiac non-thoracic elective surgery
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Acute Kidney Injury after Cardiac Surgery: Prediction, Prevention, and Management. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Sreekanth R Cheruku,Jacob Raphael,Javier A Neyra,Amanda A Fox
Acute kidney injury (AKI) is a common complication in cardiac surgery patients, with a reported incidence of 20 to 30%. The development of AKI is associated with worse short- and long-term mortality, and longer hospital length of stay. The pathogenesis of cardiac surgery-associated AKI is poorly understood but likely involves an interplay between preoperative comorbidities and perioperative stressors
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Evolving Perspectives on Esophagectomy Care: Clinical Update. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Jacob C Jackson,Daniela Molena,David Amar
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Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Stephan G Frangakis,Mark MacEachern,T Adam Akbar,Christian Bolton,Victor Lin,Albert V Smith,Chad M Brummett,Mark C Bicket
BACKGROUND Postsurgical pain is a key component of surgical recovery. However, the genetic drivers of postsurgical pain remain unclear. A broad review and meta-analyses of variants of interest will help investigators understand the potential effects of genetic variation. METHODS This article is a systematic review of genetic variants associated with postsurgical pain in humans, assessing association
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Practice Guidelines for Preoperative Fasting: Comment. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Deepak Gupta
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Practice Guidelines for Preoperative Fasting: Reply. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Basem B Abdelmalak,Girish P Joshi,Karen B Domino
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Agreement of Posttetanic Count between Monitors: Comment. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Michael M Todd
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Agreement of Posttetanic Count between Monitors: Reply. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Hee Jung Baik
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Dabigatran in Rabbit Cardiopulmonary Bypass: Reply. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Michael P Eaton,Sergiy M Nadtochiy,Ronald E Angona
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Dabigatran in Rabbit Cardiopulmonary Bypass: Comment. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Gabor Erdoes,Andreas Koster,Jerrold H Levy
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Focused Cardiac Ultrasound Identification of Dynamic Left Ventricular Outflow Tract Obstruction. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Ethan Garrigan,Grace McCarthy,Russell J Krom,Yuriy S Bronshteyn
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Ropivacaine Promotes Axon Regeneration by Regulating Nav1.8-mediated Macrophage Signaling after Sciatic Nerve Injury in Rats. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Yongchen Cui,Xiaofeng Wang,Yang Xu,Yue Cao,Gang Luo,Zhe Zhao,Junfeng Zhang
BACKGROUND Continuous nerve block with ropivacaine is commonly performed after repair surgery for traumatic peripheral nerve injuries. After peripheral nerve injury, tetrodotoxin-resistant voltage-gated sodium channel Nav1.8 is upregulated and contributes to macrophage inflammation. This study investigated whether ropivacaine promotes peripheral nerve regeneration through Nav1.8-mediated macrophage
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Neurocognitive Effect of Biased µ-Opioid Receptor Agonist Oliceridine, a Utility Function Analysis and Comparison with Morphine. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Laurence Moss,Hemme Hijma,Mark Demitrack,Jessica Kim,Geert Jan Groeneveld,Monique van Velzen,Marieke Niesters,Erik Olofsen,Albert Dahan
BACKGROUND Oliceridine (Olinvyk) is a μ-opioid receptor agonist that in contrast to conventional opioids preferentially engages the G-protein-coupled signaling pathway. This study was designed to determine the utility function of oliceridine versus morphine based on neurocognitive tests and cold pressor test. METHODS The study had a randomized, double-blind, placebo-controlled, partial block three-way
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Evidence-based Perioperative Practice Utilization among Various Racial Populations-A Retrospective Cohort Trending Analysis of Lower Extremity Total Joint Arthroplasty Patients. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Jiabin Liu,Haoyan Zhong,Michael Reynolds,Alex Illescas,Crispiana Cozowicz,Christopher L Wu,Jashvant Poeran,Stavros Memtsoudis
BACKGROUND Various studies have demonstrated racial disparities in perioperative care and outcomes. The authors hypothesize that among lower extremity total joint arthroplasty patients, evidence-based perioperative practice utilization increased over time among all racial groups, and that standardized evidence-based perioperative practice care protocols resulted in reduction of racial disparities and
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ASA Consensus-based Guidance on Preoperative Management of Patients on Glucagon-like Peptide-1 Receptor Agonists. Anesthesiology (IF 8.8) Pub Date : 2023-11-20 Deepu S Ushakumari,Robert N Sladen
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Damage Control Resuscitation in Traumatic Hemorrhage: It is More Than Fixing the Holes and Filling the Tank. Anesthesiology (IF 8.8) Pub Date : 2023-11-20 Justin E Richards,Deborah M Stein,Thomas M Scalea
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Predictors of Low Risk for Delirium during Anesthesia Emergence. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Srdjan Dragovic,Gerhard Schneider,Paul S García,Dominik Hinzmann,Jamie Sleigh,Stephan Kratzer,Matthias Kreuzer
BACKGROUND Processed electroencephalography (EEG) is used to monitor the level of anesthesia, and it has shown the potential to predict the occurrence of delirium. While emergence trajectories of relative EEG band power identified post hoc show promising results in predicting a risk for a delirium, they are not easily transferable into an online predictive application. This article describes a low-resource
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Association of Labor Neuraxial Analgesia with Maternal Blood Transfusion. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Jean Guglielminotti,Ruth Landau,Jamie Daw,Alexander M Friedman,Guohua Li
BACKGROUND Labor neuraxial analgesia may reduce the odds of postpartum hemorrhage, the leading indication for maternal blood transfusion during childbirth. This study tested the hypothesis that labor neuraxial analgesia is associated with reduced odds of maternal blood transfusion overall. METHODS U.S. birth certificate data in the Natality File of the National Vital Statistics System for all 50 states
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Contribution of µ Opioid Receptor-expressing Dorsal Horn Interneurons to Neuropathic Pain-like Behavior in Mice. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Yanmei Qi,Tyler S Nelson,Pranav Prasoon,Christopher Norris,Bradley K Taylor
BACKGROUND Intersectional genetics have yielded tremendous advances in our understanding of molecularly identified subpopulations and circuits within the dorsal horn in neuropathic pain. The authors tested the hypothesis that spinal µ opioid receptor-expressing neurons (Oprm1-expressing neurons) contribute to behavioral hypersensitivity and neuronal sensitization in the spared nerve injury model in
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Electrical Impedance Tomography Identifies Evolution of Regional Perfusion in a Porcine Model of Acute Respiratory Distress Syndrome. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Kevin T Martin,Yi Xin,Timothy G Gaulton,Marcus Victor,Roberta R Santiago,Taehwan Kim,Caio C A Morais,Aubrey A Kazimi,Marc Connell,Sarah E Gerard,Jacob Herrmann,Ariel L Mueller,Austin Lenart,Jiacheng Shen,Sherbano S Khan,Mihail Petrov,Kristan Reutlinger,Karina Rozenberg,Marcelo Amato,Lorenzo Berra,Maurizio Cereda
BACKGROUND Bedside electrical impedance tomography could be useful to visualize evolving pulmonary perfusion distributions when acute respiratory distress syndrome worsens or in response to ventilatory and positional therapies. In experimental acute respiratory distress syndrome, this study evaluated the agreement of electrical impedance tomography and dynamic contrast-enhanced computed tomography
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Opioid-free anesthesia protocol on the early quality of recovery after major surgery (SOFA trial): A randomized clinical trial. Anesthesiology (IF 8.8) Pub Date : 2023-11-17 Maxime Léger,Tristan Perrault,Solène Pessiot-Royer,Elsa Parot-Schinkel,Fabienne Costerousse,Emmanuel Rineau,Sigismond Lasocki
BACKGROUND Opioid-free anesthesia (OFA) is increasingly being adopted to reduce opioid consumption, but its impact on early postoperative recovery following major surgery has not been evaluated in comparative trials. We hypothesized that an OFA protocol would enhance the early quality of recovery (QoR) for patients undergoing scheduled major surgery under general anesthesia. METHODS The SOFA study
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A Quality Improvement Initiative to Reduce Adverse Effects of Transitions of Anesthesia Care on Postoperative Outcomes: A Retrospective Cohort Study. Anesthesiology (IF 8.8) Pub Date : 2023-11-17 Amit K Saha,Scott Segal
BACKGROUND An intraoperative transfer of care from one anesthesia provider to another, or handover, may result in information loss and contribute to adverse patient outcomes. In 2019 we undertook a quality improvement effort to increase the use of a structured intraoperative handover tool incorporated in the electronic medical record. We hypothesized that intraoperative handovers of anesthesia care
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Recruitment-to-inflation Ratio Assessed through Sequential End-expiratory Lung Volume Measurement in Acute Respiratory Distress Syndrome. Anesthesiology (IF 8.8) Pub Date : 2023-12-01 Domenico Luca Grieco,Gabriele Pintaudi,Filippo Bongiovanni,Gian Marco Anzellotti,Luca Salvatore Menga,Melania Cesarano,Antonio M Dell'Anna,Tommaso Rosá,Luca Delle Cese,Giuseppe Bello,Valentina Giammatteo,Veronica Gennenzi,Eloisa S Tanzarella,Salvatore L Cutuli,Gennaro De Pascale,Andrea De Gaetano,Salvatore M Maggiore,Massimo Antonelli
BACKGROUND Positive end-expiratory pressure (PEEP) benefits in acute respiratory distress syndrome are driven by lung dynamic strain reduction. This depends on the variable extent of alveolar recruitment. The recruitment-to-inflation ratio estimates recruitability across a 10-cm H2O PEEP range through a simplified maneuver. Whether recruitability is uniform or not across this range is unknown. The
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Prediction of Complications and Prognostication in Perioperative Medicine: A Systematic Review and PROBAST Assessment of Machine Learning Tools. Anesthesiology (IF 8.8) Pub Date : 2023-11-09 Pietro Arina,Maciej R Kaczorek,Daniel A Hofmaenner,Walter Pisciotta,Patricia Refinetti,Mervyn Singer,Evangelos B Mazomenos,John Whittle
BACKGROUND The utilization of artificial intelligence and machine learning as diagnostic and predictive tools in perioperative medicine holds great promise. Indeed, many studies have been performed in recent years to explore the potential. The purpose of this systematic review is to assess the current state of machine learning in perioperative medicine, its utility in prediction of complications and
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The effect of extracerebral contamination on near infrared spectroscopy as revealed during organ donation: A prospective observational study in brain dead organ donors. Anesthesiology (IF 8.8) Pub Date : 2023-11-07 Martin Soehle,Juliane Langer,Ehrenfried Schindler,Steffen Manekeller,Mark Coburn,Marcus Thudium
BACKGROUND Near-infrared spectroscopy (NIRS) has been utilized widely in anesthesia and intensive care to monitor regional cerebral oxygen saturation (rScO2). A normal oxygenation of extracerebral tissues may overlay and thereby mask cerebral desaturations, a phenomenon known as extracerebral contamination. We investigated the effect of a cessation of extracerebral tissue perfusion on rScO2 in patients
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Trust the Gold Standard: All Glucagon-like Peptide-1 Receptor Agonists Can Delay Gastric Emptying. Anesthesiology (IF 8.8) Pub Date : 2023-11-07 Marissa M Weber
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Hematoma with Airway Compromise after Thyroidectomy. Anesthesiology (IF 8.8) Pub Date : 2023-11-06 Jamel Ortoleva,F Thurston Drake,Amy Moor,Rafael Ortega
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U.S. Attending Anesthesiologist Burnout in the Postpandemic Era. Anesthesiology (IF 8.8) Pub Date : 2023-11-06 Anoushka M Afonso,Joshua B Cadwell,Steven J Staffa,Jina L Sinskey,Amy E Vinson
BACKGROUND Anesthesiologists are experiencing unprecedented levels of workplace stress and staffing shortages. This analysis aims to assess how U.S. attending anesthesiologist burnout changed since the onset of the COVID-19 pandemic and target well-being efforts. METHODS The authors surveyed the American Society of Anesthesiologists' U.S. attending anesthesiologist members in November 2022. Burnout
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Measuring and Comparing Clinical Productivity of Individual Anesthesiologists. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Amr E Abouleish,Charles W Whitten,Mark E Hudson
Measuring and comparing clinical productivity of individual anesthesiologists is confounded by anesthesiologist-independent factors, including facility-specific factors (case duration, anesthetizing site utilization, type of surgical procedure, and non-operating room locations), staffing ratio, number of calls, and percentage of clinical time providing anesthesia. Further, because anesthesia care is
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Balanced Billing Legislation and the Invisible Hand of Adam Smith. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Avery Tung,Jonathan Gal,Amr Abouleish
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Risk of Euglycemic Diabetic Ketoacidosis in Patients Taking Sodium Glucose Transporter 2 Inhibitors Undergoing Endoscopies. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Benjamin Steinhorn,Scott Cao,James Richter,Rodger White,Jeanine Wiener-Kronish
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Early Fibrinogen Replacement to Treat the Endotheliopathy of Trauma: Novel Resuscitation Strategies in Severe Trauma. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 David J Douin,Ana Fernandez-Bustamante
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Severe Achalasia Could Present with Subtle Symptoms. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Jan Ngian,Thangavelautham Suhitharan,Suneel Ramesh Desai,Christopher W Liu
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Patient Well-being and Satisfaction after General or Local Anesthesia with Conscious Sedation: A Secondary Analysis of the SOLVE-TAVI Trial. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Matthias Heringlake,Astrid Ellen Berggreen,Ursula Vigelius-Rauch,Sascha Treskatsch,Jörg Ender,Holger Thiele
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Anesthesia-induced Brain Oscillations and Vulnerability to Postoperative Neurocognitive Disorders. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Rodrigo Gutiérrez,Patrick L Purdon
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Difficult Airway Management in Neonates: Reply. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 James Joseph Thomas
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Difficult Airway Management in Neonates: Comment. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Takashi Asai
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Monitoring and Antagonism of Neuromuscular Blockade: Problems with Succinylcholine. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Patrick Wong,Oliver Ashby
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A Gray Future: The Role of the Anesthesiologist in Hybrid Warfare. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Fredrik Granholm,Derrick Tin,Leilani Doyle,Gregory Ciottone
During the last few decades, the increasing use of asymmetric and multimodal tactics by terrorists has led anesthesiologists worldwide to analyze and discuss their role in mass casualty scenarios in more depth. Now anesthesiologists must address the new situation of hybrid threats and hybrid warfare. This will have a direct impact on anesthesiology and intensive care, and in the end, the health and
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"You Look Young! Are You a Doctor?" A Qualitative Content Analysis of Anesthesiology Resident Responses to Ageism in Clinical Encounters. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Morgan D Stosic,Danielle Blanch-Hartigan,Mollie A Ruben,Elaine C Meyer,Ariel Henig,David B Waisel,Richard H Blum
BACKGROUND Healthcare trainees frequently report facing comments from their patients pertaining to their age. Exposure to ageist comments from patients may be related to greater stress and/or burnout in residents and may impact the quality of the resident-patient relationship. However, little empirical work has examined ageism expressed toward anesthesiology residents in clinical care, and therefore
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Baseline Intraoperative Left Ventricular Diastolic Function Is Associated with Postoperative Atrial Fibrillation after Cardiac Surgery. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Lisa Q Rong,Antonino Di Franco,Mohammed Rahouma,Arnaldo Dimagli,Aneri Patel,Alexandra J Lopes,Maria Walline,June Chan,David Chadow,Roberto Perezgrovas Olaria,Giovanni Soletti,Jiwon Kim,Richard B Devereux,Kane O Pryor,Leonard N Girardi,Jonathan W Weinsaft,Mario Gaudino
BACKGROUND Detailed understanding of the association between intraoperative left atrial and left ventricular diastolic function and postoperative atrial fibrillation is lacking. In this post hoc analysis of the Posterior Left Pericardiotomy for the Prevention of Atrial Fibrillation after Cardiac Surgery (PALACS) trial, we aimed to evaluate the association of intraoperative left atrial and left ventricular
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Velo-epiglottic Adhesion: An Unusual Finding in a Mallampati Zero Airway. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Peter L Kovacs,Zachary B Deutch,Daniel Castillo
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Development of a Prediction Score for Evaluation of Extubation Readiness in Neurosurgical Patients with Mechanical Ventilation. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Shan-Shan Xu,Ye Tian,Yan-Juan Ma,Yi-Min Zhou,Ying Tian,Ran Gao,Yan-Lin Yang,Linlin Zhang,Jian-Xin Zhou
BACKGROUND There is no widely accepted consensus on the weaning and extubating protocols for neurosurgical patients, leading to heterogeneity in clinical practices and high rates of delayed extubation and extubation failure-related health complications. METHODS In this single-center prospective observational diagnostic study, mechanically ventilated neurosurgical patients with extubation attempts were
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Indoleamine 2,3-Dioxygenase Deletion to Modulate Kynurenine Pathway and to Prevent Brain Injury after Cardiac Arrest in Mice. Anesthesiology (IF 8.8) Pub Date : 2023-11-01 Aurora Magliocca,Carlo Perego,Francesca Motta,Giulia Merigo,Edoardo Micotti,Davide Olivari,Francesca Fumagalli,Jacopo Lucchetti,Marco Gobbi,Alessandra Mandelli,Roberto Furlan,Markus B Skrifvars,Roberto Latini,Giacomo Bellani,Fumito Ichinose,Giuseppe Ristagno
BACKGROUND The catabolism of the essential amino acid tryptophan to kynurenine is emerging as a potential key pathway involved in post-cardiac arrest brain injury. The aim of this study was to evaluate the effects of the modulation of kynurenine pathway on cardiac arrest outcome through genetic deletion of the rate-limiting enzyme of the pathway, indoleamine 2,3-dioxygenase. METHODS Wild-type and indoleamine
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Prolonged Opioid Use and Pain after Surgery: Comment. Anesthesiology (IF 8.8) Pub Date : 2023-10-31 Akash Patel,Usmaan Al-Shehab
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Prolonged Opioid Use and Pain after Surgery: Reply. Anesthesiology (IF 8.8) Pub Date : 2023-10-31 Kai Kuck,Nathan L Pace,Bhiken I Naik,Karen B Domino,Karen L Posner,Leif Saager
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Prolonged Opioid Use and Pain after Surgery: Comment. Anesthesiology (IF 8.8) Pub Date : 2023-10-31 Jacques E Chelly
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Increasing levels of positive end-expiratory pressure cause stepwise biventricular stroke work reduction in a porcine model. Anesthesiology (IF 8.8) Pub Date : 2023-10-31 Gregory Wood,Tobias Lynge Madsen,Won Yong Kim,Mads Dam Lyhne
BACKGROUND Positive end-expiratory pressure (PEEP) is commonly applied to avoid atelectasis and improve oxygenation in patients during general anesthesia but affects cardiac pressures, volumes and loading conditions through cardiorespiratory interactions. PEEP may therefore alter stroke work which is the area enclosed by the pressure-volume loop and corresponds to the external work performed by the
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Target controlled infusion of remimazolam in healthy volunteers shows some acute tolerance. Anesthesiology (IF 8.8) Pub Date : 2023-10-27 Remco Vellinga,Jeroen V Koomen,Douglas J Eleveld,Thomas Stöhr,Marija Pesic,Michel M R F Struys,Pieter J Colin
BACKGROUND Remimazolam exhibits sedative properties by binding to γ-aminobutyric acid type A receptors. Remimazolam is administered as bolus dose or continuous infusion, but has not been studied using target-controlled infusion (TCI). We quantified the relationship between the remimazolam concentration, modified observers assessment of alertness and sedation (MOAAS) score and bispectral index (BIS)
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Baseline gastric volume of fasting diabetic patients is not higher than that of non-diabetics. A cross-sectional non-inferiority study. Anesthesiology (IF 8.8) Pub Date : 2023-10-26 Anahi Perlas,Maggie Zx Xiao,George Tomlinson,Binu Jacob,Sara Abdullah,Richelle Kruisselbrink,Vincent Ws Chan
BACKGROUND The physiology of diabetes mellitus can increase the risk of perioperative aspiration but there is limited and contradictory evidence on the incidence of "full stomach" in fasting diabetic patients. The aim of this study is to assess the baseline gastric content (using gastric ultrasound) in diabetic and non-diabetic patients, scheduled for elective surgery, who have followed standard pre-operative
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Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study. Anesthesiology (IF 8.8) Pub Date : 2023-10-16 Michael F Aziz,Katie Schenning,Seiji Koike,Avital O'Glasser,Vikas N O'Reilly-Shah,Valerie Sera,Michael Mathis
BACKGROUND Surgical procedures performed on patients with recent exposure to COVID-19 infection have been associated with increased mortality risk in prior studies. Accordingly, elective surgery is often delayed after infection. We aimed to compare 30-day hospital mortality and postoperative complications (acute kidney injury, pulmonary complications) of surgical patients with a prior COVID-19 infection
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Long-term outcomes with spinal versus general anesthesia for hip fracture surgery: A randomized trial. Anesthesiology (IF 8.8) Pub Date : 2023-10-13 Emily A Vail,Rui Feng,Frederick Sieber,Jeffrey L Carson,Susan S Ellenberg,Jay Magaziner,Derek Dillane,Edward R Marcantonio,Daniel I Sessler,Sabry Ayad,Trevor Stone,Steven Papp,Derek Donegan,Samir Mehta,Eric S Schwenk,Mitchell Marshall,J Douglas Jaffe,Charles Luke,Balram Sharma,Syed Azim,Robert Hymes,Ki-Jinn Chin,Richard Sheppard,Barry Perlman,Joshua Sappenfield,Ellen Hauck,Ann Tierney,Annamarie D Horan
BACKGROUND The effects of spinal versus general anesthesia on long-term outcomes have not been well-studied. We tested the hypothesis that spinal anesthesia is associated with better long-term survival and functional recovery than general anesthesia. METHODS We conducted a pre-specified analysis of long-term outcomes of a completed randomized superiority trial that compared spinal anesthesia versus
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Development of post-anesthesia care unit delirium is associated with differences in aperiodic and periodic alpha parameters of the EEG during emergence from general anesthesia - results from a prospective observational cohort study. Anesthesiology (IF 8.8) Pub Date : 2023-10-10 Julian Ostertag,Antonia Engelhard,Rachel Nuttall,Duygu Aydin,Gerhard Schneider,Paul S García,Dominik Hinzmann,Jamie W Sleigh,Stephan Kratzer,Matthias Kreuzer
BACKGROUND Intraoperative alpha-band power in frontal electrodes may provide helpful information about the balance of hypnosis and analgesia and has been associated with reduced occurrence of delirium in the post-anesthesia care unit (PACU). Recent studies suggest that narrow-band power computations from neural power spectra can benefit from separating periodic and aperiodic components of the EEG.