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Circular RNA circZFPM2 regulates cardiomyocyte hypertrophy and survival Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-04-19 Dimyana Neufeldt, Arne Schmidt, Elisa Mohr, Dongchao Lu, Shambhabi Chatterjee, Maximilian Fuchs, Ke Xiao, Wen Pan, Sarah Cushman, Christopher Jahn, Malte Juchem, Hannah Jill Hunkler, Giuseppe Cipriano, Bjarne Jürgens, Kevin Schmidt, Sonja Groß, Mira Jung, Jeannine Hoepfner, Natalie Weber, Roger Foo, Andreas Pich, Robert Zweigerdt, Theresia Kraft, Thomas Thum, Christian Bär
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Exercise training decreases lactylation and prevents myocardial ischemia–reperfusion injury by inhibiting YTHDF2 Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-04-02 Gui-e Xu, Pujiao Yu, Yuxue Hu, Wensi Wan, Keting Shen, Xinxin Cui, Jiaqi Wang, Tianhui Wang, Caiyue Cui, Emeli Chatterjee, Guoping Li, Dragos Cretoiu, Joost P. G. Sluijter, Jiahong Xu, Lijun Wang, Junjie Xiao
Exercise improves cardiac function and metabolism. Although long-term exercise leads to circulating and micro-environmental metabolic changes, the effect of exercise on protein post-translational lactylation modifications as well as its functional relevance is unclear. Here, we report that lactate can regulate cardiomyocyte changes by improving protein lactylation levels and elevating intracellular
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Role of inflammatory signaling pathways involving the CD40–CD40L–TRAF cascade in diabetes and hypertension—insights from animal and human studies Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-30 Lea Strohm, Andreas Daiber, Henning Ubbens, Roopesh Krishnankutty, Matthias Oelze, Marin Kuntic, Omar Hahad, Veronique Klein, Imo E. Hoefer, Alex von Kriegsheim, Hartmut Kleinert, Dorothee Atzler, Philipp Lurz, Christian Weber, Philipp S. Wild, Thomas Münzel, Christoph Knosalla, Esther Lutgens, Steffen Daub
CD40L–CD40–TRAF signaling plays a role in atherosclerosis progression and affects the pathogenesis of coronary heart disease (CHD). We tested the hypothesis that CD40L–CD40–TRAF signaling is a potential therapeutic target in hyperlipidemia, diabetes, and hypertension. In mouse models of hyperlipidemia plus diabetes (db/db mice) or hypertension (1 mg/kg/d angiotensin-II for 7 days), TRAF6 inhibitor
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Metabolic changes contribute to maladaptive right ventricular hypertrophy in pulmonary hypertension beyond pressure overload: an integrative imaging and omics investigation Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-27
Abstract Right ventricular (RV) failure remains the strongest determinant of survival in pulmonary hypertension (PH). We aimed to identify relevant mechanisms, beyond pressure overload, associated with maladaptive RV hypertrophy in PH. To separate the effect of pressure overload from other potential mechanisms, we developed in pigs two experimental models of PH (M1, by pulmonary vein banding and M2
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Insulin and glycolysis dependency of cardioprotection by nicotinamide riboside Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-25
Abstract Decreased nicotinamide adenine dinucleotide (NAD+) levels contribute to various pathologies such as ageing, diabetes, heart failure and ischemia–reperfusion injury (IRI). Nicotinamide riboside (NR) has emerged as a promising therapeutic NAD+ precursor due to efficient NAD+ elevation and was recently shown to be the only agent able to reduce cardiac IRI in models employing clinically relevant
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Early microvascular coronary endothelial dysfunction precedes pembrolizumab-induced cardiotoxicity. Preventive role of high dose of atorvastatin Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-23 Panagiotis Efentakis, Angeliki Choustoulaki, Grzegorz Kwiatkowski, Aimilia Varela, Ioannis V. Kostopoulos, George Tsekenis, Ioannis Ntanasis-Stathopoulos, Anastasios Georgoulis, Constantinos E. Vorgias, Harikleia Gakiopoulou, Alexandros Briasoulis, Constantinos H. Davos, Nikolaos Kostomitsopoulos, Ourania Tsitsilonis, Meletios Athanasios Dimopoulos, Evangelos Terpos, Stefan Chłopicki, Maria Gavriatopoulou
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Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia–reperfusion: role of TSPO and STAR Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-22 Juliette Bréhat, Shirin Leick, Julien Musman, Jin Bo Su, Nicolas Eychenne, Frank Giton, Michael Rivard, Louis-Antoine Barel, Chiara Tropeano, Frederica Vitarelli, Claudio Caccia, Valerio Leoni, Bijan Ghaleh, Sandrine Pons, Didier Morin
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Oxidation–reduction imaging of myoglobin reveals two-phase oxidation in the reperfused myocardium Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-18 Sally Badawi, Clémence Leboullenger, Matthieu Chourrout, Yves Gouriou, Alexandre Paccalet, Bruno Pillot, Lionel Augeul, Radu Bolbos, Antonino Bongiovani, Nathan Mewton, Thomas Bochaton, Michel Ovize, Meryem Tardivel, Mazen Kurdi, Emmanuelle Canet-Soulas, Claire Crola Da Silva, Gabriel Bidaux
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Characterizing the immune response to myocardial infarction in pigs Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-15 Florian Schnitter, Franziska Stangl, Elisabeth Noeske, Maya Bille, Anja Stadtmüller, Niklas Vogt, Florian Sicklinger, Florian Leuschner, Anna Frey, Laura Schreiber, Stefan Frantz, Niklas Beyersdorf, Gustavo Ramos, Nadine Gladow, Ulrich Hofmann
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Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-14
Abstract Anthracyclines are highly potent anti-cancer drugs, but their clinical use is limited by severe cardiotoxic side effects. The impact of anthracycline-induced cardiotoxicity (AIC) on left ventricular (LV) microarchitecture and diffusion properties remains unknown. This study sought to characterize AIC by cardiovascular magnetic resonance diffusion tensor imaging (DTI). Mice were treated with
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Pathophysiology and clinical relevance of atrial myopathy Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-12 Michiel R. L. Tubeeckx, Gilles W. De Keulenaer, Hein Heidbuchel, Vincent F. M. Segers
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Role of CD4+ T-cells for regulating splenic myelopoiesis and monocyte differentiation after experimental myocardial infarction Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-04 Nadine Gladow, Claudia Hollmann, Johannes Weirather, Xin Ding, Matthias Burkard, Sabrina Uehlein, Richa Bharti, Konrad Förstner, Thomas Kerkau, Niklas Beyersdorf, Stefan Frantz, Gustavo Ramos, Ulrich Hofmann
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Crosstalk of human coronary perivascular adipose-derived stem cells with vascular cells: role of tissue factor Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-03-02 Gemma Arderiu, Maria Teresa Bejar, Anna Civit-Urgell, Esther Peña, Lina Badimon
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Exercise, cancer, and the cardiovascular system: clinical effects and mechanistic insights Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-02-14 Simon Wernhart, Tienush Rassaf
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Distinct cytoskeletal regulators of mechanical memory in cardiac fibroblasts and cardiomyocytes Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-02-13 Nesrine Bouhrira, Alexia Vite, Kenneth B. Margulies
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The interplay of collagen, macrophages, and microcalcification in atherosclerotic plaque cap rupture mechanics Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-02-08 Imke Jansen, Rachel Cahalane, Ranmadusha Hengst, Ali Akyildiz, Eric Farrell, Frank Gijsen, Elena Aikawa, Kim van der Heiden, Tamar Wissing
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Mineralocorticoid receptor promotes cardiac macrophage inflammaging Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-02-08 Daniela Fraccarollo, Robert Geffers, Paolo Galuppo, Johann Bauersachs
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Statins affect human iPSC-derived cardiomyocytes by interfering with mitochondrial function and intracellular acidification Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-02-02 Tim Somers, Sailay Siddiqi, Renee G. C. Maas, Joost P. G. Sluijter, Jan W. Buikema, Petra H. H. van den Broek, Tanne J. Meuwissen, Wim J. Morshuis, Frans G. M. Russel, Tom J. J. Schirris
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Macrophage profiling in atherosclerosis: understanding the unstable plaque Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-01-20
Abstract The development and rupture of atherosclerotic plaques is a major contributor to myocardial infarctions and ischemic strokes. The dynamic evolution of the plaque is largely attributed to monocyte/macrophage functions, which respond to various stimuli in the plaque microenvironment. To this end, macrophages play a central role in atherosclerotic lesions through the uptake of oxidized low-density
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Lysophosphatidic acid contributes to myocardial ischemia/reperfusion injury by activating TRPV1 in spinal cord Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-01-18 Chao Wu, Meiyan Sun, Muge Qile, Yu Zhang, Liu Liu, Xueying Cheng, Xiaoxiao Dai, Eric R. Gross, Ye Zhang, Shufang He
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Macrophage-based therapeutic approaches for cardiovascular diseases Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-01-03
Abstract Despite the advances in treatment options, cardiovascular disease (CVDs) remains the leading cause of death over the world. Chronic inflammatory response and irreversible fibrosis are the main underlying pathophysiological causes of progression of CVDs. In recent decades, cardiac macrophages have been recognized as main regulatory players in the development of these complex pathophysiological
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Mast cell stabilizer, an anti-allergic drug, reduces ventricular arrhythmia risk via modulation of neuroimmune interaction Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-01-03 Yuhong Wang, Zhihao Liu, Wenjie Zhou, Jun Wang, Rui Li, Chen Peng, Liying Jiao, Song Zhang, Zhihao Liu, Zhongyang Yu, Ji Sun, Qiang Deng, Shoupeng Duan, Wuping Tan, Yijun Wang, Lingpeng Song, Fuding Guo, Zhen Zhou, Yueyi Wang, Liping Zhou, Hong Jiang, Lilei Yu
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Acute antiarrhythmic effects of SGLT2 inhibitors–dapagliflozin lowers the excitability of atrial cardiomyocytes Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-01-03 Amelie Paasche, Felix Wiedmann, Manuel Kraft, Fitzwilliam Seibertz, Valerie Herlt, Pablo L. Blochberger, Natasa Jávorszky, Moritz Beck, Leo Weirauch, Timon Seeger, Antje Blank, Walter E. Haefeli, Rawa Arif, Anna L. Meyer, Gregor Warnecke, Matthias Karck, Niels Voigt, Norbert Frey, Constanze Schmidt
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Pinacidil ameliorates cardiac microvascular ischemia–reperfusion injury by inhibiting chaperone-mediated autophagy of calreticulin Basic Res. Cardiol. (IF 9.5) Pub Date : 2024-01-02 Muyin Liu, Su Li, Ming Yin, Youran Li, Jinxiang Chen, Yuqiong Chen, You Zhou, Qiyu Li, Fei Xu, Chunfeng Dai, Yan Xia, Ao Chen, Danbo Lu, Zhangwei Chen, Juying Qian, Junbo Ge
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Targeted ablation of the left middle cervical ganglion prevents ventricular arrhythmias and cardiac injury induced by AMI Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-12-28 Meng Zheng, Siyu Chen, Ziyue Zeng, Huanhuan Cai, Hanyu Zhang, Xiaomei Yu, Weina Wang, Xianqing Li, Chen-Ze Li, Bo He, Ke-Qiong Deng, Zhibing Lu
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Stimulating cardiac glucose oxidation lessens the severity of heart failure in aged female mice Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-12-26 Qiuyu Sun, Cory S. Wagg, Berna Güven, Kaleigh Wei, Amanda A. de Oliveira, Heidi Silver, Liyan Zhang, Ander Vergara, Brandon Chen, Nathan Wong, Faqi Wang, Jason R. B. Dyck, Gavin Y. Oudit, Gary D. Lopaschuk
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Thrombospondin 1 and Reelin act through Vldlr to regulate cardiac growth and repair Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-12-26
Abstract Adult mammalian cardiomyocytes have minimal cell cycle capacity, which leads to poor regeneration after cardiac injury such as myocardial infarction. Many positive regulators of cardiomyocyte cell cycle and cardioprotective signals have been identified, but extracellular signals that suppress cardiomyocyte proliferation are poorly understood. We profiled receptors enriched in postnatal cardiomyocytes
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Striated preferentially expressed gene deficiency leads to mitochondrial dysfunction in developing cardiomyocytes Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-12-26 Gu Li, He Huang, Yanshuang Wu, Chang Shu, Narae Hwang, Qifei Li, Rose Zhao, Hilaire C. Lam, William M. Oldham, Souheil EI-Chemaly, Pankaj B. Agrawal, Jie Tian, Xiaoli Liu, Mark A. Perrella
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Targeting mitochondrial shape: at the heart of cardioprotection Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-11-13 Sauri Hernandez-Resendiz, Aishwarya Prakash, Sze Jie Loo, Martina Semenzato, Kroekkiat Chinda, Gustavo E. Crespo-Avilan, Linh Chi Dam, Shengjie Lu, Luca Scorrano, Derek J. Hausenloy
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Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-11-06 Ilona Kutschka, Edoardo Bertero, Christina Wasmus, Ke Xiao, Lifeng Yang, Xinyu Chen, Yasuhiro Oshima, Marcus Fischer, Manuela Erk, Berkan Arslan, Lin Alhasan, Daria Grosser, Katharina J. Ermer, Alexander Nickel, Michael Kohlhaas, Hanna Eberl, Sabine Rebs, Katrin Streckfuss-Bömeke, Werner Schmitz, Peter Rehling, Thomas Thum, Takahiro Higuchi, Joshua Rabinowitz, Christoph Maack, Jan Dudek
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The role of glycolytic metabolic pathways in cardiovascular disease and potential therapeutic approaches Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-11-08 Shuxian Chen, Yuanming Zou, Chunyu Song, Kexin Cao, Kexin Cai, Yanjiao Wu, Zhaobo Zhang, Danxi Geng, Wei Sun, Nanxiang Ouyang, Naijin Zhang, Zhao Li, Guozhe Sun, Yixiao Zhang, Yingxian Sun, Ying Zhang
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Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-11-03 Sandhya Singh, Aakash Gaur, Rakesh Kumar Sharma, Renu Kumari, Shakti Prakash, Sunaina Kumari, Ayushi Devendrasingh Chaudhary, Pankaj Prasun, Priyanka Pant, Hannah Hunkler, Thomas Thum, Kumaravelu Jagavelu, Pragya Bharati, Kashif Hanif, Pragya Chitkara, Shailesh Kumar, Kalyan Mitra, Shashi Kumar Gupta
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Splenic monocytes mediate inflammatory response and exacerbate myocardial ischemia/reperfusion injury in a mitochondrial cell-free DNA-TLR9-NLRP3-dependent fashion Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-10-09 Dina Xie, Hanliang Guo, Mingbiao Li, Liqun Jia, Hao Zhang, Degang Liang, Naishi Wu, Zequan Yang, Yikui Tian
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Succinate dehydrogenase is essential for epigenetic and metabolic homeostasis in hearts Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-10-11 Wenwen Li, Li Quan, Kun Peng, Yanru Wang, Xianhua Wang, Quan Chen, Heping Cheng, Qi Ma
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Outcomes of hypothalamic oxytocin neuron-driven cardioprotection after acute myocardial infarction Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-10-06 Kathryn J. Schunke, Jeannette Rodriguez, Jhansi Dyavanapalli, John Schloen, Xin Wang, Joan Escobar, Grant Kowalik, Emily C. Cheung, Caitlin Ribeiro, Rebekah Russo, Bridget R. Alber, Olga Dergacheva, Sheena W. Chen, Alejandro E. Murillo-Berlioz, Kyongjune B. Lee, Gregory Trachiotis, Emilia Entcheva, Christine A. Brantner, David Mendelowitz, Matthew W. Kay
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Recent advances on the role of monoamine oxidases in cardiac pathophysiology Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-10-04 Nina Kaludercic, Ruth Jepchirchir Arusei, Fabio Di Lisa
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Mitophagy for cardioprotection Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-10-05 Allen Sam Titus, Eun-Ah Sung, Daniela Zablocki, Junichi Sadoshima
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Novel GSDMD inhibitor GI-Y1 protects heart against pyroptosis and ischemia/reperfusion injury by blocking pyroptotic pore formation Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-10-02 Lingfeng Zhong, Jibo Han, Xiaoxi Fan, Zhouqing Huang, Lan Su, Xueli Cai, Shuang Lin, Xudong Chen, Weijian Huang, Shanshan Dai, Bozhi Ye
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Giant mitochondria in cardiomyocytes: cellular architecture in health and disease Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-09-29 Amy Li, Gerald J. Shami, Lisa Griffiths, Sean Lal, Helen Irving, Filip Braet
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The roles of intracellular proteolysis in cardiac ischemia–reperfusion injury Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-09-28 Bridgette Hartley, Wesam Bassiouni, Richard Schulz, Olivier Julien
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Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-09-09 Casper Homilius, Jacob Marthinsen Seefeldt, Julie Sørensen Axelsen, Tina Myhre Pedersen, Trine Monberg Sørensen, Roni Nielsen, Henrik Wiggers, Jakob Hansen, Vladimir V. Matchkov, Hans Erik Bøtker, Ebbe Boedtkjer
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Myeloperoxidase is a critical mediator of anthracycline-induced cardiomyopathy Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-09-01 Felix Sebastian Nettersheim, Johannes David Schlüter, Wiebke Kreuzberg, Dennis Mehrkens, Simon Grimm, Harshal Nemade, Simon Braumann, Alexander Hof, Henning Guthoff, Vera Peters, Friedrich Felix Hoyer, Yulia Kargapolova, Jan-Wilm Lackmann, Stefan Müller, Christian P. Pallasch, Michael Hallek, Agapios Sachinidis, Matti Adam, Holger Winkels, Stephan Baldus, Simon Geißen, Martin Mollenhauer
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Cardiac fibroblast GSK-3α aggravates ischemic cardiac injury by promoting fibrosis, inflammation, and impairing angiogenesis Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-09-01 Prachi Umbarkar, Suma Ejantkar, Sulivette Y. Ruiz Ramirez, Angelica Toro Cora, Qinkun Zhang, Sultan Tousif, Hind Lal
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Preventing mitochondrial reverse electron transport as a strategy for cardioprotection Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-08-28 Hiran A. Prag, Michael P. Murphy, Thomas Krieg
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Identification of the specific molecular and functional signatures of pre-beta-HDL: relevance to cardiovascular disease Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-08-28 Isabelle Guillas, Marie Lhomme, Cédric Pionneau, Lucrèce Matheron, Maharajah Ponnaiah, Sophie Galier, Sandrine Lebreton, Marie Delbos, Feng Ma, Maryam Darabi, Petra El Khoury, Marianne Abifadel, Philippe Couvert, Philippe Giral, Philippe Lesnik, Maryse Guerin, Wilfried Le Goff, Anatol Kontush
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Perspective: mitochondrial STAT3 in cardioprotection Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-08-24 Petra Kleinbongard
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Rivaroxaban attenuates neutrophil maturation in the bone marrow niche Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-08-14 R. Schneckmann, M. Döring, S. Gerfer, S. Gorressen, S. Heitmeier, C. Helten, A. Polzin, C. Jung, M. Kelm, A. C. Fender, U. Flögel, M. Grandoch
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Matrix metalloproteinase-2 proteolyzes mitofusin-2 and impairs mitochondrial function during myocardial ischemia–reperfusion injury Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-07-26 Wesam Bassiouni, Robert Valencia, Zabed Mahmud, John M. Seubert, Richard Schulz
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The heterocellular heart: identities, interactions, and implications for cardiology Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-07-26 Achim Lother, Peter Kohl
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Endothelial ILK induces cardioprotection by preventing coronary microvascular dysfunction and endothelial-to-mesenchymal transition Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-07-14 P. Reventun, S. Sánchez-Esteban, A. Cook-Calvete, M. Delgado-Marín, C. Roza, S. Jorquera-Ortega, I. Hernandez, L. Tesoro, L. Botana, J. L. Zamorano, C. Zaragoza, M. Saura
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A tale of pigs, beta-blockers and genetic variants. Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-07-13 Borja Ibáñez
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Three-vessel coronary infusion of cardiosphere-derived cells for the treatment of heart failure with preserved ejection fraction in a pre-clinical pig model Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-07-03 Romain Gallet, Jin-Bo Su, Daphné Corboz, Paul-Matthieu Chiaroni, Alain Bizé, Jianping Dai, Mathieu Panel, Pierre Boucher, Gaëtan Pallot, Juliette Brehat, Lucien Sambin, Guillaume Thery, Nadir Mouri, Aurélien de Pommereau, Pierre Denormandie, Stéphane Germain, Alain Lacampagne, Emmanuel Teiger, Eduardo Marbán, Bijan Ghaleh
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Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-06-28 Eshita Varma, Jana Burghaus, Thomas Schwarzl, Thileepan Sekaran, Parul Gupta, Agnieszka A. Górska, Christoph Hofmann, Claudia Stroh, Lonny Jürgensen, Verena Kamuf-Schenk, Xue Li, Rebekka Medert, Florian Leuschner, Vivien Kmietczyk, Marc Freichel, Hugo A. Katus, Matthias W. Hentze, Norbert Frey, Mirko Völkers
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No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-06-08 Petra Kleinbongard, Helmut Raphael Lieder, Andreas Skyschally, Gerd Heusch
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The RISK pathway leading to mitochondria and cardioprotection: how everything started Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-05-26 Derek M. Yellon, Siavash Beikoghli Kalkhoran, Sean M. Davidson
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Deficiency of mitochondrial calcium uniporter abrogates iron overload-induced cardiac dysfunction by reducing ferroptosis Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-05-25 Nadezhda Fefelova, Suwakon Wongjaikam, Sri Harika Pamarthi, Natthaphat Siri-Angkul, Thomas Comollo, Anshu Kumari, Vivek Garg, Andreas Ivessa, Siriporn C. Chattipakorn, Nipon Chattipakorn, Judith K. Gwathmey, Lai-Hua Xie
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SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-05-22 Marta W. Szulik, Steven Valdez, Maureen Walsh, Kathryn Davis, Ryan Bia, Emilee Horiuchi, Sean O’Very, Anil K. Laxman, Linda Sandaklie-Nicolova, David R. Eberhardt, Jessica R. Durrant, Hanin Sheikh, Samuel Hickenlooper, Magnus Creed, Cameron Brady, Mickey Miller, Li Wang, June Garcia-Llana, Christopher Tracy, Stavros G. Drakos, Katsuhiko Funai, Dipayan Chaudhuri, Sihem Boudina, Sarah Franklin
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In-ovo echocardiography for application in cardiovascular research Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-05-16 Niklas Hegemann, Willem Bintig, Paul-Lennard Perret, Judith Rees, Alessandra Viperino, Britta Eickholt, Wolfgang M. Kuebler, Michael Höpfner, Bianca Nitzsche, Jana Grune
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Matrix metalloproteinases in coronary artery disease and myocardial infarction Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-05-09 Hanna Bräuninger, Saskia Krüger, Lucas Bacmeister, Alexander Nyström, Kilian Eyerich, Dirk Westermann, Diana Lindner
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Multilineage contribution of CD34+ cells in cardiac remodeling after ischemia/reperfusion injury Basic Res. Cardiol. (IF 9.5) Pub Date : 2023-05-05 Jun Xie, Liujun Jiang, Junzhuo Wang, Yong Yin, Ruilin Wang, Luping Du, Ting Chen, Zhichao Ni, Shuaihua Qiao, Hui Gong, Biao Xu, Qingbo Xu