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Use of Respiratory and Contact Precautions to Decrease the Spread of SARS-CoV-2 Infection Was Not Associated with a Decrease in Endometritis–Intra-Amniotic Infection Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-24 Jacqueline Roig, Chelsea A. DeBolt, Mariela Cabrera, Emily Spiera, Cody Goldberger, Angela Bianco, Joanne A. Stone, Stephanie H. Factor
Objective To decrease the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the Mount Sinai Hospital's obstetric service, additional contact and respiratory precautions for patients and staff were implemented. Patients were allowed only one support person, SARS-CoV-2 tested on admission, and required to mask during hospitalization. Staff were required to wear masks and eye shields
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Pregnancy Outcomes in Women Who Developed Elevated Blood Pressure and Stage I Hypertension after 20 Weeks Gestation Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-23 Helen Woolcock, Natalia Parra, Yijia Zhang, Uma M. Reddy, Natalie A. Bello, Eliza Miller, Whitney A. Booker
Objective The American College of Obstetrics threshold for hypertension (≥140/90 mm Hg) differs from those of the American College of Cardiology (ACC) and the American Heart Association (AHA). It is unknown if ACC/AHA hypertension levels are associated with adverse pregnancy outcomes (APOs) after 20 weeks gestation. The purpose of this study is to analyze APOs in women with blood pressure (BP) in the
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Patient Perspectives on Outpatient versus Inpatient Cervical Ripening for Induction of Labor Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-23 Amber Watters, Etoroabasi Ekpe, Annette Okafor, Emily Donelan
Objective Our objective was to compare patient perceived control and experience with outpatient versus inpatient cervical ripening. Study Design This is a retrospective mixed-methods analysis of a quality improvement initiative focused on the impact to patients of incorporating outpatient cervical ripening into routine practice. Postpartum inpatients who had elected for outpatient cervical ripening
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The Association between Sickle Cell Disease and Postpartum Severe Maternal Morbidity Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-23 Natalie E. Poliektov, Danielle M. Vuncannon, Thoa K. Ha, Michael K. Lindsay, Suchitra Chandrasekaran
Objective To compare the risk of severe maternal morbidity (SMM) from the delivery admission to 42 days' postdischarge among persons with sickle cell disease (SCD) to those without SCD. Study Design This retrospective cohort study included deliveries ≥20 weeks' gestation at an urban safety net hospital in Atlanta, GA from 2011 to 2019. The exposure was SCD diagnosis. The outcome was a composite of
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Exploring the Limits of Artificial Intelligence for Referencing Scientific Articles Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-23 Emily M. Graf, Jordan A. McKinney, Alexander B. Dye, Lifeng Lin, Luis Sanchez-Ramos
Objective To evaluate the reliability of three artificial intelligence (AI) chatbots (ChatGPT, Google Bard, and Chatsonic) in generating accurate references from existing obstetric literature. Study Design Between mid-March and late April 2023, ChatGPT, Google Bard, and Chatsonic were prompted to provide references for specific obstetrical randomized controlled trials (RCTs) published in 2020. RCTs
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Gestational Age-Specific Markers Associated with Postnatal Intervention in Fetal Suspicion of Coarctation of the Aorta Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-23 Sam Amar, Shiran S. Moore, Punnanee Wutthigate, Amanda Ohayon, Daniela V. Martinez, Jessica Simoneau, Claudia Renaud, Gabriel Altit
Objective Fetal diagnosis of coarctation of the aorta (CoA) is currently associated with a high false-positive rate. Many predictive markers may be gestational age (GA)-specific. We sought to establish GA-specific traditional and speckle-tracking fetal echocardiography (STE) markers predictive of true CoA in neonates with prenatal suspicion. Study Design This is a retrospective case–control study.
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Factors Associated with Maternal Morbidity among Black Women in the United States Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-19 Catrine Ibrahim Sous, William Moravec, Emily DeFranco, Elizabeth A. Kelly, Robert M. Rossi
Objective Non-Hispanic Black people (NHBP) have a three-fold higher rate of maternal mortality compared to other racial groups. Racial disparities in maternal morbidity are well-described; however, there are substantial differences in cultural, economic, and social determinants of health among racial groups. We thus sought to study the at-risk, non-Hispanic Black population as its own cohort to identify
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Prenatal Exposure to Acid Suppressor Medications and Development of Ductus Arteriosus in Term Newborns Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-16 Ella Segal, Daniella Landau, Lior Hassan, Adir Israeli, Rafael Gorodischer
Objective The ductus arteriosus normally closes after birth. Histamine 2 receptor antagonist (H2RA) has been associated with patent ductus arteriosus (PDA). We aimed to study the characteristics of term infants with PDA and their possible association with prenatal exposure to antacids—proton pump inhibitors (PPIs) and H2RA. Study Design This was a population-based matched case–control study of mothers
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Characteristics Associated with Trial of Labor among Patients with Twin Pregnancies Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-15 Danielle T. Cipres, Rachael B. Cowherd, Olivia H. Barry, Liqi Chen, Lynn M. Yee
Objective This study aimed to identify patient and provider factors associated with undergoing trial of labor (TOL) among eligible patients with twin gestations. Study Design This retrospective cohort study of patients with twin gestations who received care at a large tertiary care center from 2000 to 2016 included individuals with live pregnancies greater than 23 weeks of gestation and cephalic-presenting
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Postpartum Outcomes in Patients Receiving Venous Thromboembolism Prophylaxis during Antepartum Admission Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-12 Muhan Hu, Christina T. Blanchard, Angela R. Seasely, Michelle Lu, Jeff M. Szychowski, Brian Casey, Alan T. Tita, George Saade, Akila Subramaniam
Objective We evaluated if venous thromboembolism (VTE) prophylaxis in the inpatient antepartum period was associated with wound hematomas, VTE occurrence, and other adverse outcomes. Study Design This study is a secondary analysis of a retrospective cohort of patients who delivered at University of Alabama at Birmingham (UAB). Patients receiving outpatient anticoagulation (AC) were excluded. We grouped
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Predictors of Breastfeeding among Women Admitted with Severe Preeclampsia Before 34 Weeks Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-11 Sara J. Grundy, Carmen M. Avram, Jacquelyn Dillon, Alice Darling, Gregory Zemtsov, Jennifer JM Cate, Sarahn Wheeler, Sarah K. Dotters-Katz
Objective Patients with severe preeclampsia (sPREX) face barriers to successful breastfeeding (BF), including an increased risk of maternal and newborn complications, prematurity, and low birth weight. Patients with early-onset sPREX (before 34 weeks' gestation) may be at even greater risk, yet there are little data available on factors associated with BF challenges in this population. We describe
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Reevaluating Associations between Prenatal Care Utilization and Current Trends in Preterm Birth Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-11 Macie L. Champion, Elisa T. Bushman, Kimberly D. Martin, Ashley N. Battarbee, Lindsay S. Robbins, William W. Andrews, Alan T. Tita
Objective Studies have suggested an association between prenatal care (PNC) and preterm birth (PTB). We evaluated trends in PTB and association of PNC and PTB. Study Design This was a retrospective cohort study of singleton, viable nonanomalous deliveries from 1991 to 2018. PNC utilization was defined by World Health Organization using number of visits: adequate (≥8), suboptimal (5–7), and inadequate
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The Current State of Neonatal Neurodevelopmental Follow-up Programs in North America: A Children's Hospitals Neonatal Consortium Report Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-05 Vilmaris Quiñones Cardona, Susan S. Cohen, Noah Cook, Mehmet N. Cizmeci, Amit Chandel, Robert DiGeronimo, Semsa Gogcu, Eni Jano, Katsuaki Kojima, Kyong-Soon Lee, Ryan M. McAdams, Ogechukwu Menkiti, Ulrike Mietzsch, Eric Peeples, Elizabeth Sewell, Jeffrey S. Shenberger, An N. Massaro, Girija Natarajan, Rakesh Rao, Maria L. V. Dizon, on behalf of the Children's Hospitals Neonatal Consortium
Objective This study aimed to determine neonatal neurodevelopmental follow-up (NDFU) practices across academic centers. Study Design This study was a cross-sectional survey that addressed center-specific neonatal NDFU practices within the Children's Hospitals Neonatal Consortium (CHNC). Results Survey response rate was 76%, and 97% of respondents had a formal NDFU program. Programs were commonly staffed
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Trial of Labor versus Repeat Cesarean Delivery in Individuals with Morbid Obesity after Previous Cesarean Delivery Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-04 Misooja Lee, Tawany C. Almeida, George Saade, Tetsuya Kawakita
Objective This study aimed to compare adverse neonatal outcomes associated with the trial of labor after cesarean (TOLAC) at term in pregnancies according to maternal prepregnancy body mass index (BMI; kg/m2) and the presence of previous vaginal delivery (VD). Study Design This was a repeated cross-sectional analysis of individuals with singleton, cephalic, and term deliveries with a history of one
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The Effect of an Oxytocin Decision Support Checklist on Oxytocin Use and Maternal and Neonatal Outcomes: A Retrospective Cohort Study Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-02 Nazineen Kandahari, Lue-Yen Tucker, Tina Raine-Bennett, Janelle Palacios, Allison N. Schneider, Vanitha J. Mohta
Objective To assess the association between use of an oxytocin decision support checklist with oxytocin usage and clinical outcomes. Study Design We conducted a retrospective cohort study of patients with singleton gestations at 370/7 weeks or greater who received oxytocin during labor from October 2012 to February 2017 at an integrated community health care system during three exposure periods: (1)
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Variability in Diagnosis and Management of Hypoglycemia in Neonatal Intensive Care Unit Am. J. Perinatol. (IF 2.0) Pub Date : 2024-04-02
Objective Hypoglycemia, the most common metabolic derangement in the newborn period remains a contentious issue, not only due to various numerical definitions, but also due to limited therapeutical options which either lack evidence to support their efficacy or are increasingly recognized to lead to adverse reactions in this population. This study aimed to investigate neonatologists' current attitudes
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Use of Postpartum Hemorrhage Checklist during Vaginal Deliveries: A Quality Improvement Study Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-30
Objective Postpartum hemorrhage (PPH) protocols improve patient safety and reduce utilization of blood products; however, few data exist on sustainability of PPH checklist use, how use affects care delivery, and variation of use among patient subgroups. This study aimed to (1) examine compliance with PPH checklist use during vaginal deliveries, (2) evaluate whether checklist use varied by patient and/or
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Neonatal Outcomes are Similar between Patients with Resolved and Those with Persistent Oligohydramnios Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-26 Anna R. Whelan, Phinnara Has, David A. Savitz, Valery A. Danilack, Adam K. Lewkowitz
Objective Oligohydramnios (defined as amniotic fluid volume < 5 cm or deepest vertical pocket < 2 cm) is regarded as an ominous finding on prenatal ultrasound. Amniotic fluid, however, is not static, and to date, there have been no studies comparing perinatal outcomes in patients who are diagnosed with oligohydramnios that resolves and those who have persistent oligohydramnios. Study Design This is
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A Crossover Trial Evaluating Coconut Oil as an Alternative to Commercial Ultrasound Gel in Obstetrical Ultrasounds Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-26
Objective Our objective was to evaluate the quality of obstetrical ultrasound images obtained with coconut oil compared with commercial ultrasound gel and to assess patient acceptability. Study Design This was a randomized two-period crossover study in which 40 pregnant patients had standard biometry images obtained with both coconut oil and commercial ultrasound gel during their growth or anatomy
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Perinatal Outcomes of Late Preterm Rupture of Membranes with or without Latency Antibiotics Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-26 Mais Abu Nofal, Manal Massalha, Marwa Diab, Maysa Abboud, Aya Asla Jamhour, Waseem Said, Gil Talmon, Samah Mresat, Kamel Mattar, Gali Garmi, Noah Zafran, Ari Reiss, Raed Salim
Objective This study aimed to examine whether the addition of latency antibiotics in late preterm rupture of membranes (ROM) decreases neonatal infection and increases latency. Study Design This retrospective two-center study was conducted at Holy Family Hospital (HFH) in Nazareth and Emek Medical Center (EMC) in Afula, on data collected between January 2017 and April 2023. HFH is the smaller institution
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The Cost of Developing and Implementing an Antepartum Referral Program for Penicillin Allergy Evaluation at a Single Academic Tertiary Care Hospital Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-21 Martina S. Burn, Xiao Xu, Jason Kwah, Jane Liao, Moeun Son
Objective Approximately 10% of pregnant individuals report a penicillin allergy, yet most are not truly allergic. Allergy verification during pregnancy is safe and recommended; however, many hospitals lack the infrastructure to execute testing. Our aim was to evaluate the cost of developing and implementing a penicillin allergy referral program for pregnant individuals at an academic institution and
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Increased Maternal BMI at Time of Delivery Associated with Poor Maternal and Neonatal Outcomes Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-21 Haley A. Steffen, Samantha R. Swartz, Kimberly A. Kenne, Linder H. Wendt, J. Brooks Jackson, Mary B. Rysavy
Objective Current literature on the risks and outcomes of obesity in pregnancy almost exclusively utilizes prepregnancy body mass index (BMI). Given the rising obesity rate across the United States along with a paucity of available information on the relationship between delivery BMI and maternal and neonatal outcomes, our study aimed to determine the association of maternal BMI at delivery with antepartum
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Need for Gastrostomy Tube in Periviable Infants Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-21 Erica E. ElSeed Peterson, Jared T. Roeckner, Taylor W. Deall, Michele Karn, Jose R. Duncan, Jaime Flores-Torres, Ambuj Kumar, Tara M. Randis
Objective We sought to identify clinical and demographic factors associated with gastrostomy tube (g-tube) placement in periviable infants. Study Design We conducted a single-center retrospective cohort study of live-born infants between 22 and 25 weeks' gestation. Infants not actively resuscitated and those with congenital anomalies were excluded from analysis. Results Of the 243 infants included
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Targeted Neonatal Echocardiography: Basics of Knobology 101 Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-19 Aimann Surak, Gabriel Altit, Yogen Singh
Targeted neonatal echocardiography (TNE) is essential when approaching hemodynamic instability in neonates. Competency in this field requires standardized training, including robust hands-on experience. Proficiency in understanding the key elements of ultrasound knobology is indispensable for optimal acquisition of imaging. This is a narrative review summarizing the key elements of knobology in TNE
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The Impact of Social Vulnerability on Substance Use Detection Practices in Pregnancy Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-19 Virginia A. Lijewski, Heather Aldrich, Heather L. Straub
This study aimed to synthesize current literature regarding the impact of social vulnerability on pregnancy-related substance use detection in the United States and highlight disparities in substance use detection practices. Clinicaltrials.gov, Google Scholar, PubMed (includes MEDLINE), and Cochrane Library databases were searched using the following Medical Subject Headings (MeSH): ([“pregnancy” or
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The Importance of Fetal Station in the First Stage of Labor Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-18 Sara I. Jones, Chinonye S. Imo, Amanda C. Zofkie, Alexandra S. Ragsdale, Donald D. Mcintire, David B. Nelson
Objective This study aimed to examine the relationship of fetal station in the first stage of labor to labor curves and cesarean delivery rates among women presenting in spontaneous labor. Study Design Labor curves for patients with nonanomalous singletons who presented in spontaneous labor to our hospital's Obstetric Triage Unit with intact membranes from January 1, 2012, to August 31, 2016 were reviewed
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History of Cholestasis is not Associated with Worsening Outcomes in Subsequent Pregnancy with Cholestasis Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-15 Minhazur R. Sarker, Chelsea A. Debolt, Dana Canfield, Lauren Ferrara
Objective Intrahepatic cholestasis of pregnancy is associated with adverse pregnancy outcomes including intrauterine fetal demise, spontaneous preterm labor, and meconium-stained amniotic fluid. Studies have yet to determine if patients with a history of pregnancy complicated by cholestasis had an association with more severe adverse outcomes in a subsequent pregnancy complicated by cholestasis. Study
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Design and Implementation of a Didactic Curriculum in a Large Neonatal–Perinatal Medicine Fellowship Program: A Single-center Experience Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-15 Shanmukha Mukthapuram, Beth Ann Johnson, Cara Slagle, John Erickson, Beena D. Kamath-Rayne, Jennifer M. Brady
Objective Although the Accreditation Council for Graduate Medical Education and American Board of Pediatrics (ABP) provide regulations and guidance on fellowship didactic education, each program establishes their own didactic schedules to address these learning needs. Wide variation exists in content, educators, amount of protected educational time, and the format for didactic lectures. This inconsistency
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Comparison of National Factor-based Models for Preeclampsia Screening Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-15 Louise Ghesquière, Emmanuel Bujold, Eric Dubé, Nils Chaillet
Objective This study aimed to compare the predictive values of the American College of Obstetricians and Gynecologists (ACOG), the National Institute for Health and Care Excellence (NICE), and the Society of Obstetricians and Gynecologists of Canada (SOGC) factor-based models for preeclampsia (PE) screening. Study Design We conducted a secondary analysis of maternal and birth data from 32 hospitals
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Rehospitalization Following Discharge from Newborn Nursery during Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-12 Kristen Ronca, Laura Vazquez, Eleanor Bathory, Suhas Nafday
Objective This study aimed to compare rehospitalization rates, diagnoses, and well-baby nursery (WBN) length of stay (LOS) among rehospitalized infants born during the COVID-19 pandemic to those born prior. Study Design A retrospective comparison of 215 infants rehospitalized from March 1, 2019 to March 1, 2021 was performed in an urban academic center. Rates of readmission were determined for all
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Temporal Trend in Maternal Morbidity and Comorbidity Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-12 Yara H. Diab, Jim Huang, Lea Nehme, George Saade, Tetsuya Kawakita
Objective This study aimed to examine the temporal trends of severe maternal morbidity (SMM) in the U.S. population in relation to trends in maternal comorbidity. Study Design We performed a repeated cross-sectional analysis of data from individuals at 20 weeks' gestation or greater using U.S. birth certificate data from 2011 to 2021. Our primary outcome was SMM defined as the occurrence of intensive
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Neonatal Outcomes among Fetuses with an Abdominal Circumference <3rd %ile and Estimated Fetal Weight 3rd to 9th %ile Compared to Fetuses with an EFW <3rd %ile Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-07 Rebecca Horgan, Lea Nehme, Hannah J. Jensen, Anika P. Shah, Ryan Saal, Kazuma Onishi, Tetsuya Kawakita, Juliana G. Martins, Alfred Abuhamad
Objective Fetal growth restriction (FGR) is defined as an estimated fetal weight (EFW) or abdominal circumference (AC) <10th percentile (%ile) for gestational age (GA). An EFW <3rd %ile for GA is considered severe FGR (sFGR). It remains unknown if fetuses with isolated AC <3rd %ile should be considered sFGR. Our primary objective was to assess composite neonatal outcomes in fetuses with an AC <3rd
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Trauma and Posttraumatic Stress Disorder as Important Risk Factors for Gestational Metabolic Dysfunction Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-06 Mariana Rocha, Keziah Daniels, Suchitra Chandrasekaran, Vasiliki Michopoulos
Gestational metabolic diseases adversely impact the health of pregnant persons and their offspring. Pregnant persons of color are impacted disproportionately by gestational metabolic disease, highlighting the need to identify additional risk factors contributing to racial-ethnic pregnancy-related health disparities. Trauma exposure and posttraumatic stress disorder (PTSD) are associated with increased
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Respiratory Severity Score and Neurodevelopmental Outcomes at Age 3 Years in Extremely Preterm Infants Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-06 Kei Tamai, Akihito Takeuchi, Makoto Nakamura, Naomi Matsumoto, Takashi Yorifuji, Misao Kageyama
Objective We aimed to examine the association between respiratory severity score (RSS; mean airway pressure × fraction of inspired oxygen) and neurodevelopmental outcomes in extremely preterm infants. Study Design This was a single-center, retrospective cohort study. We analyzed data from extremely preterm infants who were admitted to the neonatal intensive care unit at Okayama Medical Center between
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Continuous Neuromuscular Blockade for Bronchopulmonary Dysplasia Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-06 Emily D. Johnson, Kristopher Keppel, LeAnn McNamara, Joseph M. Collaco, Renee D. Boss
Objective Bronchopulmonary dysplasia (BPD) is the most common late morbidity for premature infants. Continuous neuromuscular blockade (CNMB) is suggested for the most unstable phase of BPD, despite no outcome data. We explored the association between duration of CNMB for severe BPD and mortality. Design Medical record review of children <5 years old admitted from 2016 to 2022 with BPD and one or more
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A Description of IVIG Use in Term Neonates with ABO Incompatibility Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-06 Michael Daunov, Andrea Schlosser, Sindhoosha Malay, Jaclyn Adams, Rachael Clark, Lauren Ferrerosa, Irina Pateva
Objective This study aimed to determine if treatment with IVIG of neonates with ABO incompatibility (without Rh incompatibility) results in decreased number of packed red blood cell (pRBC) transfusions and phototherapy use. Study Design An Institutional Review Board (IRB)-approved, single-institution retrospective study was conducted. Neonates ≥38 weeks' gestational age born between January 1, 2007
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Postnatal Steroids Use for Bronchopulmonary Dysplasia in a Quaternary Care NICU Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-04 Uthayakumaran Kanagaraj, Jason Tan, Amuchou Soraisham, Abhay Lodha, Prakesh Shah, Tapas Kulkarni, Sandesh Shivananda
Objective Intercenter variation and trends in postnatal steroids (PNS) use among preterm infants for prevention or treatment of bronchopulmonary dysplasia (BPD) is known. Understanding intracenter PNS use patterns facilitate implementation of center-specific change interventions to optimize outcomes. This study aimed to (i) quantify the proportion of infants who received PNS, and describe the timing
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Sonographic Predictors of Antepartum Bleeding in Placenta Previa Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-01
Objective To evaluate the association between sonographic features of placenta previa and vaginal bleeding (VB). Study Design Retrospective cohort study of women with placenta previa identified on ultrasound between 160/7 and 276/7 weeks gestation. Placental distance past the cervical os (DPO), placental thickness, edge angle, and cervical length (CL) were measured. The primary outcome was any VB and
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Performance of a Maternal Risk Stratification System for Predicting Low Apgar Scores Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-01 Thomas P. Kishkovich, Kaitlyn E. James, Thomas H. McCoy, Roy H. Perlis, Anjali J. Kaimal, Mark A. Clapp
Objective Maternal risk stratification systems are increasingly employed in predicting and preventing obstetric complications. These systems focus primarily on maternal morbidity, and few tools exist to stratify neonatal risk. We sought to determine if a maternal risk stratification score was associated with neonatal morbidity. Study Design Retrospective cohort study of patients with liveborn infants
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Artificial Intelligence to Determine Fetal Sex Am. J. Perinatol. (IF 2.0) Pub Date : 2024-03-01 Emily H. Frisch, Anant Jain, Mike Jin, Erik P. Duhaime, Amol Malshe, Steve Corey, Robert Allen, Nicole M. Duggan, Chanel E. Fischetti
Objective This proof-of-concept study assessed how confidently an artificial intelligence (AI) model can determine the sex of a fetus from an ultrasound image. Study Design Analysis was performed using 19,212 ultrasound image slices from a high-volume fetal sex determination practice. This dataset was split into a training set (11,769) and test set (7,443). A computer vision model was trained using
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Intimate Partner Violence and Depression Screening of Mothers with Infants in the Neonatal Intensive Care Unit Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-29 Sujata Desai, Karen Stanzo, Beverley Benskin, Kristina Cardenas, Tiffany W. Gilkey, Arpitha Chiruvolu
Objective This study aimed to determine the prevalence of partner violence and depression in neonatal intensive care unit (NICU) mothers. Study Design This was a descriptive study. Mothers were screened in a safe room away from their partner with the Edinburgh Postnatal Depression Scale (EPDS) and the Abuse Assessment Screen Tool (AAS) within 2 days of the newborn's admission. The EPDS was administered
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Heart Rate Variability as a Prognostic Tool for Gastroschisis Infants in the Neonatal Intensive Critical Unit Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-28 Chioma Moneme, Sherry L. Kausch, Briana M. Belmonte, Mark A. Fleming II, Daniel E. Levin, Brynne A. Sullivan
Objective Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics (HRCs) such as decreased variability occur due to the inflammatory response to sepsis in preterm infants. This study aimed to test the hypothesis that infants with gastroschisis
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Maternal Hemodynamics from Preconception to Delivery: Research and Potential Diagnostic and Therapeutic Implications: Position Statement by Italian Association of Pre-Eclampsia and Italian Society of Perinatal Medicine Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-28 Barbara Vasapollo, Sara Zullino, Gian Paolo Novelli, Daniele Farsetti, Serena Ottanelli, Sara Clemenza, Massimo Micaglio, Enrico Ferrazzi, Daniela Denis Di Martino, Tullio Ghi, Elvira Di Pasquo, Rossana Orabona, Paola Corbella, Maria Grazia Frigo, Federico Prefumo, Tamara Stampalija, Stefano Raffaele Giannubilo, Herbert Valensise, Federico Mecacci
Objective The Italian Association of Preeclampsia (AIPE) and the Italian Society of Perinatal Medicine (SIMP) developed clinical questions on maternal hemodynamics state of the art. Study Design AIPE and SIMP experts were divided in small groups and were invited to propose an overview of the existing literature on specific topics related to the clinical questions proposed, developing, wherever possible
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Reference Ranges for Regional Cerebral Oxygen Saturation with Masimo O3® after Birth and Differences with Other Devices Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-27 Luis Bachiller Carnicero, Sonia Caserío Carbonero
Objective Cerebral oximetry using near-infrared spectroscopy (NIRS) is a noninvasive optical technology widely used in neonatology. The present study aimed to define reference ranges for cerebral tissue oxygen saturation (crSO2) with a new four-wavelength NIRS device, Masimo O3® oximeter, during immediate transition after birth and compare values with those obtained previously with NIRO 200NX®. Study
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Gut Microbiota and Neonatal Acute Kidney Injury Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-26
Objective To characterize the relationship between gut microbiota and neonatal acute kidney injury biomarkers based on the gut-kidney axis. Study Design The Pubmed database was primarily searched to include relevant literature on gut microbiota and neonatal acute kidney injury biomarkers, which was subsequently organized and analyzed and a manuscript was written. Results Gut microbiota was associated
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Infection and Sepsis Trends during United States' Delivery Hospitalizations from 2000 to 2020 Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-26 Lilly Y. Liu, Alexander M. Friedman, Dena Goffman, Lisa Nathan, Jean-Ju Sheen, Uma M. Reddy, Mary E. D'Alton, Timothy Wen
Objective This study aimed to evaluate trends, risk factors, and outcomes associated with infections and sepsis during delivery hospitalizations in the United States. Study Design The 2000–2020 National Inpatient Sample was used for this repeated cross-sectional analysis. Delivery hospitalizations of patients aged 15 to 54 with and without infection and sepsis were identified. Common infection diagnoses
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Are Racial Disparities in Cesarean Due to Differences in Labor Induction Management? Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-26
Objective While there are known racial disparities in cesarean delivery (CD) rates, the exact etiologies for these disparities are multifaceted. We aimed to determine if differences in induction of labor (IOL) management contribute to these disparities. Study Design This retrospective cohort study evaluated all nulliparous patients with an unfavorable cervix and intact membranes who underwent IOL of
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Impact of Congenital Heart Disease on the Outcomes of Very Low Birth Weight Infants Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-26 Xuxin Chen, Shazia Bhombal, David M. Kwiatkowski, Michael Ma, Valerie Y. Chock
Objective To investigate the association of congenital heart disease (CHD) with morbidity and mortality of very low birth weight (VLBW) infants. Study Design This matched case–control study included VLBW infants born at a single institution between 2001 and 2015. The primary outcome was mortality. Secondary outcomes included necrotizing enterocolitis, bronchopulmonary dysplasia (BPD), sepsis, retinopathy
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The Impact of the COVID-19 Pandemic on Respiratory Syncytial Virus Infection in the Neonatal Period Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-26 Sinem Akbay Ak, Buse Soysal, Ezgi Yangın Ergon, Oguz Han Kalkanlı, Yuce Ayhan, Senem Alkan Ozdemir, Sebnem Calkavur, Tulin Gokmen Yıldırım
Objective Respiratory syncytial virus (RSV) is the most common viral respiratory infection in infants. This study aimed to establish the potential changes in the clinical course of RSV in the neonatal period with the onset of the coronavirus disease 2019(COVID-19) pandemic. Study Design During the observational study period, newborns diagnosed with community-acquired RSV infection and admitted to the
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Development of a Prediction Model for Surgery or Early Mortality at the Time of Initial Assessment for Necrotizing Enterocolitis Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-20 Sujir P. Nayak, Mariela Sánchez-Rosado, Jordan D. Reis, L. Steven Brown, Kate L. Mangona, Priya Sharma, David B. Nelson, Myra H. Wyckoff, Samir Pandya, Imran N. Mir, Luc P. Brion
Objective No available scale, at the time of initial evaluation for necrotizing enterocolitis (NEC), accurately predicts, that is, with an area under the curve (AUC) ≥0.9, which preterm infants will undergo surgery for NEC stage III or die within a week. Study Design This is a retrospective cohort study (n = 261) of preterm infants with <33 weeks' gestation or <1,500 g birthweight with either suspected
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Sleep Quality in Individuals with and without Persistent Postpartum Hypertension Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Tiffany L. Wang, Samantha G. Bryan, Arundhathi Jeyabalan, Francesca L. Facco, Robin E. Gandley, Carl A. Hubel, Janet M. Catov, Alisse K. Hauspurg
Objective This study aimed to compare sleep quality at 1 year postpartum following a hypertensive disorder of pregnancy (HDP) among individuals with persistent postpartum hypertension (HTN) compared with those with normal blood pressures (BPs). Study Design We combined data from the Heart Health 4 New Moms pilot randomized trial (n = 118) and the Pathways prospective cohort study (n = 36). Individuals
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Implementation of In-Hospital Postpartum Glucose Tolerance Testing for People with Gestational Diabetes Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Nina K. Ayala, Audra C. Fain, Megan M. Smith, Lauren E. Schlichting, Maureen S. Hamel, Erika F. Werner
Objective We aimed to evaluate uptake of the glucose tolerance test performed during delivery hospitalization as part of routine clinical care. Study Design This is a retrospective cohort study of people with GDM at a tertiary center. We collected 9 months of postimplementation data after the in-hospital (“early”) glucose tolerance test was adopted as a routine screening option. Adherence was compared
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Immediate Postpartum Breastfeeding Following Pregnancy with Cardiac Disease Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Yolanda Tinajero, Nisha I. Parikh, Ian S. Harris, Juan M. Gonzalez, Anushree Agarwal, Nasim C. Sobhani
Objective This study aimed to identify predictors of immediate postpartum breastfeeding among women with maternal cardiac disease (MCD). Study Design This study included all gravidas with MCD who delivered at a single institution from 2012 to 2018. Charts were abstracted for maternal demographics, obstetrical outcome, cardiac diagnoses, cardiac risk stratification scores, and prepregnancy echocardiogram
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Risk Profiling In Vitro Fertilization Pregnancies that Develop Placenta Accreta Spectrum Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Anna M. Modest, Brett D. Einerson, Albaro J. Nieto, Vineet K. Shrivastava, Alireza A. Shamshirsaz, Scott A. Shainker, on behalf of the Pan American Society for Placenta Accreta Spectrum
Objective The objective of this study is to assess whether, among a cohort of placenta accreta spectrum (PAS) patients, antenatal suspicion of PAS was less likely in in vitro fertilization (IVF) compared with non-IVF patients. In addition, we aimed to assess whether IVF patients exhibited similar risk factors for PAS compared with non-IVF patients. Study Design This is an international multicenter
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NuMoM2b Study Insights: Primary Exposures, Outcomes, and Directions for Future Research Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Leanna Kragenbrink, Claire M. Schopper, Rebecca B. McNeil, William A. Grobman, Robert M. Silver, David M. Haas
Objective To summarize the publications to date from a large obstetric cohort of nulliparous individuals. Study design We summarized all of the publications from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b). We descriptively summarized the most common outcomes and exposures reported in current publications. Results Fifty-six publications to date are discussed. The most
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Early-Pregnancy Resilience Characteristics Before Versus During the COVID-19 Pandemic Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Nina K. Ayala, Audra C. Fain, Tess E.K. Cersonsky, Erika F. Werner, Emily S. Miller, Melissa A. Clark, Adam K. Lewkowitz
Objective Resilience is associated with mental and somatic health benefits. Given the social, physical, and mental health toll of the coronavirus disease 2019 (COVID-19) pandemic, we examined whether the COVID-19 pandemic was associated with population-level changes in resilience among pregnant people. Study Design Secondary analysis of a prospective cohort of nulliparous pregnant people <20 weeks'
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Optimal Delivery Management for the Prevention of Early Neonatal SARS-CoV-2 Infection: Systematic Review and Meta-analysis Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19
Objective Delivery management interventions (DMIs) were recommended to prevent delivery-associated transmission of maternal SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) to infants without evidence of effect on early neonatal SARS-CoV-2 infection (ENI) and neonatal death <28 days of life (ND). This systematic review describes different DMI combinations and the frequency of ENI and ND
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Variability in Practice and Implementation of Oxygen Target Saturation Policies in United States' Neonatal Intensive Care Units Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19
Objective This study aimed to describe target oxygen saturation (SpO2) ranges used for premature infants in United States' neonatal intensive care units (NICUs) and to describe if these target SpO2 ranges have changed in recent years. Study Design A 29-question survey focused on target SpO2 practices and policies was distributed via the NICU medical directors listservs for the American Academy of Pediatrics
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Infant Mortality Categorized by Birth Weight Percentiles for Deliveries Between 22 and 28 Weeks of Gestation Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-19 Kazuma Onishi, Christiana Bitas, Tetsuya Kawakita
Objective Our objective was to describe infant mortality within 1 year of life according to gestational age and birth weight percentile in infants delivered between 22 and 28 weeks of gestation. Study Design This study was a retrospective cohort study based on publicly available U.S. birth certificate data linked to infant death data between 2014 and 2020. Maternal–neonate pairs of singleton live births
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Factors Associated with the Uptake of Long-acting Reversible Contraception and Contraceptive Use in Postpartum People with HIV at a Single Tertiary Care Center Am. J. Perinatol. (IF 2.0) Pub Date : 2024-02-16 Lara Youniss, Lilian Bui, Helen Cejtin, Julie Schmidt, Ashish Premkumar
Objective This study aimed to elucidate factors contributing to uptake of highly effective contraception, including permanent contraception, and no contraceptive plan among postpartum people with HIV (PWHIV). Study Design A retrospective cohort analysis was conducted to correlate postpartum birth control (PPBC) with sociodemographic and biomedical variables among postpartum PWHIV who received care