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Is choline deficiency an unrecognized factor in necrotizing enterocolitis of preterm infants? Pediatr. Res. (IF 3.6) Pub Date : 2024-04-24 Douglas C. Drenckpohl, Danielle N. Christifano, Susan E. Carlson
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ECI biocommentary: Shiraz Badurdeen Pediatr. Res. (IF 3.6) Pub Date : 2024-04-24 Shiraz Badurdeen
My introduction to neonatology was as an Academic Clinical Fellow in the Oxford Deanery. This fellowship afforded me the opportunity to travel and experience newborn care in Kenya and Sri Lanka. My commitment to the specialty was sealed when I realised that the conditions affecting newborns were remarkably similar all over the world. I was offered the opportunity to take the definitive step towards
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Hirschsprung’s disease: m6A methylase VIRMA suppresses cell migration and proliferation by regulating GSK3β Pediatr. Res. (IF 3.6) Pub Date : 2024-04-24 Yang Yang, Mengzhen Zhang, Nan Li, Chen Wang, Huirong Yang, Xinwei Hou, Jiaming Yang, Kaisi Fan, Liucheng Yang, Kai Wu
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GFRA4 improves the neurogenic potential of enteric neural crest stem cells via hedgehog pathway Pediatr. Res. (IF 3.6) Pub Date : 2024-04-24 Fangfang Zhang, Mingyu Cui, Lijuan Zhang, Bangzhen Ma, Feng Guo, Gang Wang
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Young hearts, early risks: novel cardiovascular biomarkers in former very preterm infants at kindergarten age Pediatr. Res. (IF 3.6) Pub Date : 2024-04-24 Wolfgang Mitterer, Irena Odri Komazec, Eva Huber, Benedikt Schaefer, Anna Posod, Ursula Kiechl-Kohlendorfer
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Regional variability in therapeutic hypothermia eligibility criteria for neonatal hypoxic-ischemic encephalopathy Pediatr. Res. (IF 3.6) Pub Date : 2024-04-22 Jacopo Proietti, Geraldine B. Boylan, Brian H. Walsh
Abstract Early induced therapeutic hypothermia represents the cornerstone treatment in neonates with probable hypoxic-ischemic encephalopathy. The selection of patients for treatment usually involves meeting criteria indicating evidence of perinatal hypoxia-ischemia and the presence of moderate or severe encephalopathy. In this review, we highlight the variability that exists between some of the different
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Commentary on the challenges of modeling hepatoblastoma in-vivo Pediatr. Res. (IF 3.6) Pub Date : 2024-04-22 Edward H. Hurley
Hepatoblastoma is the most common primary liver cancer in the United States.1 The mainstay for treatment includes surgical resection, chemotherapy and in extreme cases liver transplantation, which collectively has lead to a greater than 80% overall survival rate. Cornet et al. asks two related and very important questions: will resecting hepatoblastoma induce growth in residual tumor and in distant
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Association of obesity and menarche SNPs and interaction with environmental factors on precocious puberty Pediatr. Res. (IF 3.6) Pub Date : 2024-04-22 Peng Xue, Jianfei Lin, Jingyi Tang, Yao Chen, Tingting Yu, Chang Chen, Huijun Kong, Cuilan Lin, Shijian Liu
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Caffeine: how early is too early? Pediatr. Res. (IF 3.6) Pub Date : 2024-04-20 Ryan Kilpatrick, Jonathan M. Davis, Jacob V. Aranda
In contrast to older children and adults, premature neonates have decreased sensitivity to carbon dioxide and often experience hypoxic ventilatory depression. This can result in deleterious and prolonged periods of hypoventilation and apnea in response to hypoxemia. Caffeine is a trimethylxanthine which stimulates the respiratory control centers in the medulla through competitive inhibition of adenosine
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Body composition and motor function in children born large for gestational age at term Pediatr. Res. (IF 3.6) Pub Date : 2024-04-20 Yuji Ito, Tadashi Ito, Sho Narahara, Hideshi Sugiura, Yuichiro Sugiyama, Tetsuo Hattori, Hiroyuki Kidokoro, Takeshi Tsuji, Tetsuo Kubota, Jun Natsume, Koji Noritake, Nobuhiko Ochi
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Sleep and internalizing problems in primary school children with attention-deficit hyperactivity disorder Pediatr. Res. (IF 3.6) Pub Date : 2024-04-18 Han-Yu Dong, Chun-Yue Miao, Yang Xue, Yu Zhang, Ling Shan, Fei-Yong Jia, Lin Du
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The predictive value of MRI scores for neurodevelopmental outcome in infants with neonatal encephalopathy Pediatr. Res. (IF 3.6) Pub Date : 2024-04-18 Csilla Andorka, Hajnalka Barta, Timea Sesztak, Nora Nyilas, Kata Kovacs, Ludovika Dunai, Gabor Rudas, Agnes Jermendy, Miklos Szabo, Eniko Szakmar
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Stability of neurodevelopmental trajectories in moderately late and early preterm children born 15 years apart Pediatr. Res. (IF 3.6) Pub Date : 2024-04-16 Nienke H. van Dokkum, Alexander Lepe, Stef van Buuren, Sijmen A. Reijneveld, Marlou L. A. de Kroon
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Arise robot overlords! A synergy of artificial intelligence in the evolution of scientific writing and publishing Pediatr. Res. (IF 3.6) Pub Date : 2024-04-16 Dennis Ren, Damian Roland
Artificial intelligence (AI) heralds a new wave of technological advancement. The domain of scientific writing and publishing, traditionally steeped in human effort, is experiencing an unprecedented transformation through AI’s integration, particularly with Large language models (LLMs) and Generative Pre-trained Transformers (GPTs). LLMs have access to and are trained on massive amounts of data. GPTs
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Developmental characteristics and accuracy of autism screening among two-year-old toddlers in the ECHO program Pediatr. Res. (IF 3.6) Pub Date : 2024-04-15 Coral L. Shuster, Patricia A. Brennan, Brian S. Carter, Jennifer Check, Viren D’Sa, Joyce C. Graff, Jennifer Helderman, Julie A. Hofheimer, Robert M. Joseph, Laura E. Murphy, Thomas G. O’Connor, T. Michael O’Shea, Michelle Pievsky, Stephen J. Sheinkopf, Lauren C. Shuffrey, Lynne M. Smith, Pei-Chi Wu, Barry M. Lester
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Umbilical cord blood culture for early onset sepsis in preterm infants Pediatr. Res. (IF 3.6) Pub Date : 2024-04-15 Brahim Bensouda, Romain Mandel, Gabriel Altit, Nabeel Ali
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Risk of childhood neoplasms related to neonatal phototherapy- a systematic review and meta-analysis Pediatr. Res. (IF 3.6) Pub Date : 2024-04-13 Ilari Kuitunen, Atte Nikkilä, Panu Kiviranta, Johanna Jääskeläinen, Anssi Auvinen
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Value of preclinical systematic reviews and meta-analyses in pediatric research Pediatr. Res. (IF 3.6) Pub Date : 2024-04-13 Olga Romantsik, Matthias Bank, Julia M. L. Menon, Atul Malhotra, Matteo Bruschettini
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Biventricular function in preterm infants with patent ductus arteriosus ligation: A three-dimensional echocardiographic study Pediatr. Res. (IF 3.6) Pub Date : 2024-04-13 Katsuaki Toyoshima, Hirosato Aoki, Takahiro Noguchi, Naka Saito, Tatsuto Shimizu, Takahiro Kemmotsu, Tomoyuki Shimokaze, Tomoko Saito, Jun Shibasaki, Motoyoshi Kawataki, Toshihide Asou, Tsuyoshi Tachibana, Satoshi Masutani
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Public perceptions of families affected by pediatric cancer and educational work in pediatric oncology Pediatr. Res. (IF 3.6) Pub Date : 2024-04-12 Andrey Reshetnikov, Margarita Gevandova, Nadezhda Prisyazhnaya, Konstantin Sobolev, Nadezhda Vyatkina, Gleb Demyanov
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Trying to get breastfeeding women out of the pharmaceutical orphanage Pediatr. Res. (IF 3.6) Pub Date : 2024-04-12 Mathijs Binkhorst, Marije Hogeveen
In this issue of the journal, Bertrand et al. report their findings on the measurement of Remdesivir and its active metabolite GS-441524 in 17 human milk samples from 4 lactating mothers taking Remdesivir in the commonly recommended dose for coronavirus disease 2019 (COVID-19).1 Based on the analysis of these samples, collected at intervals ranging from 4 h to 61 days after Remdesivir administration
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Relationship between exclusive breastfeeding, pet ownership, and infant healthcare utilization Pediatr. Res. (IF 3.6) Pub Date : 2024-04-12 Rinat M. Tal, Lauren M. Walsh, Mary G. Boyle, Emily R. Hunter, Madison R. Martin-Giacalone, Steve M. Liao, Stephanie A. Fritz, Lori R. Holtz
Although the exact mechanism is unknown, environmental exposures and their associated microbial contributions are thought to drive infant health and healthcare resource utilization, as they largely shape the immune system.1,2 For example, dietary habits, household characteristics, and daycare attendance have been shown to affect infants. Contact with pet dogs and cats has been associated with lower
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Nasal oxidative stress mediating the effects of colder temperature exposure on pediatric asthma symptoms Pediatr. Res. (IF 3.6) Pub Date : 2024-04-11 Linchen He, Christina Norris, Kimberly Palaguachi-Lopez, Karoline Barkjohn, Zhen Li, Feng Li, Yinping Zhang, Marilyn Black, Michael H. Bergin, Junfeng (Jim) Zhang
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Caregiver burden in pediatric acute kidney injury and chronic kidney disease Pediatr. Res. (IF 3.6) Pub Date : 2024-04-10 Rupesh Raina, Archana Myneni, Sidharth K. Sethi
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The impact of intermittent hypoxemia on type 1 retinopathy of prematurity in preterm infants Pediatr. Res. (IF 3.6) Pub Date : 2024-04-10 Samaneh Rabienia Haratbar, Li Chen, Qiang Cheng, Dara Singh, Faraneh Fathi, Mehrana Mohtasebi, Xuhui Liu, Abhijit Patwardhan, Prasad Bhandary, Henrietta S. Bada, Guoqiang Yu, Elie G. Abu Jawdeh
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Adequate nutrition for bronchopulmonary dysplasia, but do not forget oxygen Pediatr. Res. (IF 3.6) Pub Date : 2024-04-09 Maximo Vento
God bless …the food that cures all hunger! God bless …the food that cures all hunger!
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Prenatal, newborn and childhood factors and the timing of puberty in boys and girls Pediatr. Res. (IF 3.6) Pub Date : 2024-04-09 Maria Suutela, Matti Hero, Silja Kosola, Päivi J. Miettinen, Taneli Raivio
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Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh Pediatr. Res. (IF 3.6) Pub Date : 2024-04-08 Anne CC Lee, Sara Cherkerzian, Fahmida Tofail, Lian V. Folger, Salahuddin Ahmed, Sayedur Rahman, Nabid H. Chowdhury, Rasheda Khanam, Ingrid Olson, Emily Oken, Raina Fichorova, Charles A. Nelson, Abdullah H. Baqui, Terrie Inder
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Impact of different growth hormone levels on gut microbiota and metabolism in short stature Pediatr. Res. (IF 3.6) Pub Date : 2024-04-06 Lan Li, Yu Wang, Yinyin Huang, Yi Lu, Weiyi Wang, Xian Chen, Xiaoou Shan, Hongchang Gao, Zhihan Yan
Background Growth hormone deficiency(GHD) and idiopathic short stature(ISS) are the primary causes of short stature in children. Animal experiments have revealed a link between growth hormone(GH), gut microbiota and metabolism, however, limited information is available from human trials. Methods Fecal samples collected from GHD (n = 36), ISS (n = 32) and healthy control (HC) children(n = 16) were subjected
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Glucose-regulatory hormones and growth in very preterm infants fed fortified human milk Pediatr. Res. (IF 3.6) Pub Date : 2024-04-05 Kristine Holgersen, Martin Bo Rasmussen, Itay Zamir, Lise Aunsholt, Gitte Zachariassen, Per Torp Sangild
Background Bovine colostrum (BC) contains a range of milk bioactive components, and it is unknown how human milk fortification with BC affects glucose-regulatory hormones in very preterm infants (VPIs). This study aimed to investigate the associations between hormone concentrations and fortification type, birth weight (appropriate/small for gestational age, AGA/SGA), milk intake, postnatal age, and
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Apnea of prematurity: when is the right time to stimulate? Pediatr. Res. (IF 3.6) Pub Date : 2024-04-04 Ahmed El-Saie, Binoy Shivanna
Apnea of prematurity (AOP) remains one of the common diagnoses in neonatal intensive care units, especially with the increased survival of extremely premature infants. Multiple definitions exist for AOP, depending on the medical society. It has been defined by the American Academy of Pediatrics Committee of the Fetus and Newborn as the presence of respiratory pauses for more than 20 s or shorter pauses
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Early post-natal nutrition and renal consequences in preterm infants Pediatr. Res. (IF 3.6) Pub Date : 2024-04-04 Alberto Edefonti, Maria Cristina Mancuso
From an epidemiological perspective, the global incidence of preterm births has witnessed a steady rise worldwide, currently estimated at about 10%.1 With the improving survival rates of premature and low birth weight (LBW) newborns, the global incidence of Chronic Kidney Disease (CKD) requiring dialysis and renal transplant in both pediatric and, more significantly, adult population is destined to
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HbA1c or fructosamine on evaluating glucose intolerance in children with beta- thalassemia Pediatr. Res. (IF 3.6) Pub Date : 2024-04-04 Asmaa A. Mahmoud, Mahmoud A. El-Hawy, Esraa T. Allam, Ahmed H. Salem, Ahmed S. Abo Hola
Background Beta-thalassemia major (β-TM) patients are more likely to experience blood glucose intolerance and to date; the blood markers that could evaluate this are debatable. So, this study aimed to assess the roles of glycated hemoglobin A1c (HbA1c) and fructosamine in evaluating glucose intolerance in children with β-TM and figuring out role of insulin resistance in these patients. Methods One
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An all-inclusive model for predicting invasive bacterial infection in febrile infants age 7–60 days Pediatr. Res. (IF 3.6) Pub Date : 2024-04-04 Dustin W. Ballard, Jie Huang, Adam L. Sharp, Dustin G. Mark, Tran H. P. Nguyen, Beverly R. Young, David R. Vinson, Patrick Van Winkle, Mamata V. Kene, Adina S. Rauchwerger, Jennifer Y. Zhang, Stacy J. Park, Mary E. Reed, Tara L. Greenhow
Background Invasive bacterial infections (IBIs) in febrile infants are rare but potentially devastating. We aimed to derive and validate a predictive model for IBI among febrile infants age 7–60 days. Methods Data were abstracted retrospectively from electronic records of 37 emergency departments (EDs) for infants with a measured temperature >=100.4 F who underwent an ED evaluation with blood and urine
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Cerebral blood flow dynamics during cardiac surgery in infants Pediatr. Res. (IF 3.6) Pub Date : 2024-04-03 Martin Leth-Olsen, Gaute Døhlen, Hans Torp, Siri Ann Nyrnes
Background In this pilot study, we investigated continuous cerebral blood flow velocity measurements to explore cerebrovascular hemodynamics in infants with congenital heart disease undergoing cardiac surgery. Methods A non-invasive transfontanellar cerebral Doppler monitor (NeoDoppler) was used to monitor 15 infants (aged eight days to nine months) during cardiac surgery with cardiopulmonary bypass
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Antimicrobial exposure during infancy in a longitudinal California cohort Pediatr. Res. (IF 3.6) Pub Date : 2024-04-03 Hannah C. Barca, Jeannette Ferber, Megan Richards, Matthew Strickland, Alfred J. Fernandez, De-Kun Li, Lyndsey A. Darrow
Background To describe temporal and sociodemographic patterns of antimicrobial exposure during the first year of life in a large US cohort. Methods Singleton infants born 1998–2014 enrolled in Kaiser Permanente Northern California integrated health system (n = 345,550) were followed longitudinally via comprehensive electronic health records, capturing all systemic antimicrobial inpatient administrations
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Epigenetic modifications in the development of bronchopulmonary dysplasia: a review Pediatr. Res. (IF 3.6) Pub Date : 2024-04-03 Lichuan Wang, Jun Xiao, Bohan Zhang, Ana Hou
Abstract While perinatal medicine advancements have bolstered survival outcomes for premature infants, bronchopulmonary dysplasia (BPD) continues to threaten their long-term health. Gene–environment interactions, mediated by epigenetic modifications such as DNA methylation, histone modification, and non-coding RNA regulation, take center stage in BPD pathogenesis. Recent discoveries link methylation
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The role of nutritional interventions in the prevention and treatment of chronic lung disease of prematurity Pediatr. Res. (IF 3.6) Pub Date : 2024-04-02 Miguel Saenz de Pipaon, Leif D. Nelin, Alison Gehred, Madelaine E. Rossholt, Sissel Moltu, Chris Van den Akker, Anton H. van Kaam, Ana Sánchez, Minesh Khashu, Charles C. Roehr, Virgilio Carnielli
Abstract Chronic lung disease of prematurity or bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Nutrition may affect incidence and severity of BPD. In this context, the Section on Nutrition, Gastroenterology and Metabolism, the Pulmonary Section of the European Society for Paediatric Research (ESPR) and SPR have joined forces to review the current knowledge on nutritional
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Quality of life and socioeconomic and educational status in patients with congenital hypothyroidism Pediatr. Res. (IF 3.6) Pub Date : 2024-04-02 Emmi Danner, Reijo Sund, Harri Sintonen, Laura Niuro, Harri Niinikoski, Hanna Huopio, Liisa A. Viikari, Jarmo Jääskeläinen
Background The aim of this study was to investigate the influence of primary congenital hypothyroidism (CH) on quality of life, level of education and socioeconomic status (SES). Methods Two independent study cohorts, a national and a regional, were collected from Finnish national registers and patient records. Data on social security benefits, SES, marital status, and education were collected from
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Risk factors for infection and outcomes in infants with neonatal encephalopathy: a cohort study Pediatr. Res. (IF 3.6) Pub Date : 2024-04-02 David Odd, Hemmen Sabir, Simon A. Jones, Chris Gale, Ela Chakkarapani
Background To determine the association between early infection risk factors and short-term outcomes in infants with neonatal encephalopathy following perinatal asphyxia (NE). Methods A retrospective population-based cohort study utilizing the National Neonatal Research Database that included infants with NE admitted to neonatal units in England and Wales, Jan 2008–Feb 2018. Exposure: one or more of
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Arginine-NO metabolites are associated with morbidity in single ventricle infants undergoing stage 2 palliation Pediatr. Res. (IF 3.6) Pub Date : 2024-04-02 Benjamin S. Frank, Sierra Niemiec, Ludmila Khailova, Christopher A. Mancuso, Tanner Lehmann, Max B. Mitchell, Gareth J. Morgan, Mark Twite, Michael V. DiMaria, Jelena Klawitter, Jesse A. Davidson
Background Infants with single ventricle heart disease (SVHD) suffer morbidity from insufficient pulmonary blood flow, which may be related to impaired arginine metabolism. No prior study has reported quantitative mapping of arginine metabolites to evaluate the relationship between circulating metabolite levels and outcomes. Methods Prospective cohort study of 75 SVHD cases peri-Stage 2 and 50 healthy
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Citrate anticoagulation and systemic heparin anticoagulation during continuous renal replacement therapy among critically-ill children Pediatr. Res. (IF 3.6) Pub Date : 2024-03-30 Seyma Koksal Atis, Muhterem Duyu, Zeynep Karakaya, Alev Yilmaz
Bakcground The aim of this study was to evaluate the efficacy and safety of citrate versus heparin anticoagulation for CRRT in critically-ill children. Methods This retrospective comparative cohort reviewed the clinical records of critically-ill children undergoing CRRT with either RCA or systemic heparin anticoagulation. The primary outcome measure was hemofilter survival time. Secondary outcomes
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Prepuberty is a window period for curcumin to prevent obesity in postnatal overfed rats Pediatr. Res. (IF 3.6) Pub Date : 2024-03-28 Susu Du, Nan Zhou, Wen Zheng, Xiaolei Zhu, Ru Ling, Wei Zhou, Xiaonan Li
Background Overnutrition in early life increases the risk of obesity and metabolic diseases. We investigated the effects and the window period of a curcumin (CUR) diet on postnatal overfed rats. Methods Male rats aged 3 days were randomly divided into normal litters (NL, 10 pups/litter) and small litters (SL, 3 pups/litter). After weaning (Week 3, W3), NL rats were fed a normal diet (NL) and SL rats
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Centering pediatric research, advocacy, and clinical care around early relational health Pediatr. Res. (IF 3.6) Pub Date : 2024-03-27 Genevieve G. Guyol, Joyce R. Javier
On behalf of the Pediatric Policy Council: Shetal Shah (Chair), Joyce Javier, Lois Lee, Mona Patel, Lisa Chamberlain, Tina Cheng, David Keller, Maya Ragavan, Ann Reed. “Early Relational Health is the state of emotional well-being that grows from emotional connection between babies and toddlers and their parents and caregivers when they experience strong, positive, and nurturing relationships with each
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Has telemedicine come to fruition? Parents’ and pediatricians’ perceptions and preferences regarding telemedicine Pediatr. Res. (IF 3.6) Pub Date : 2024-03-30 Nadia M. Bajwa, Noelle Junod Perron, Olivia Braillard, Sophia Achab, Patricia Hudelson, Melissa Dominicé Dao, Robin Lüchinger, Sanae Mazouri-Karker
Background Telemedicine has increasingly become a viable option for patient care and may increase access to care. The aim of our study was to evaluate both parent and pediatrician perceptions, preferences, and acceptability regarding the use of different telemedicine modalities. Methods We conducted a cross-sectional survey of both parents and pediatricians in Geneva, Switzerland in 2021. The questionnaire
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Perinatal compromise affects development, form, and function of the hippocampus part one; clinical studies Pediatr. Res. (IF 3.6) Pub Date : 2024-03-22 Tegan A. White, Suzanne L. Miller, Amy E. Sutherland, Beth J. Allison, Emily J. Camm
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Unveiling the impact of maternal gestational diabetes mellitus on cord blood CD71+ erythroid cell transcriptome Pediatr. Res. (IF 3.6) Pub Date : 2024-03-22 Min Yin, Yan Zhang, Xinyu Li, Xia Li
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“The forest and the trees”: a narrative medicine curriculum by residents for residents Pediatr. Res. (IF 3.6) Pub Date : 2024-03-22 Anoushka Sinha, Carly S. Slater, Alyson Lee, Harini Sridhar, Deepthiman Gowda
Abstract A 7-session narrative medicine (NM) curriculum was designed and facilitated by pediatrics residents for pediatrics residents in order to unpack challenging experiences during clinical training and strengthen relationships with colleagues and patients. The primary facilitator, a resident with a master’s degree in NM, provided facilitator training to her co-residents with whom she co-led the
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Perinatal compromise affects development, form, and function of the hippocampus part two; preclinical studies Pediatr. Res. (IF 3.6) Pub Date : 2024-03-22 Tegan A. White, Suzanne L. Miller, Amy E. Sutherland, Beth J. Allison, Emily J. Camm
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Combining activity and grimace scores reflects perinatal stability in infants <32 weeks gestational age Pediatr. Res. (IF 3.6) Pub Date : 2024-03-22 Zachary Tuttle, Calum Roberts, Peter Davis, Atul Malhotra, Kenneth Tan, Risha Bhatia, Lindsay Zhou, Elizabeth Baker, Kate Hodgson, Douglas Blank
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Viral infections in pregnancy and impact on offspring neurodevelopment: mechanisms and lessons learned Pediatr. Res. (IF 3.6) Pub Date : 2024-03-20 Emma F. Yates, Sarah B. Mulkey
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Glycogen storage disease type V: a still under-recognized condition lacking definitive genotype-phenotype correlates Pediatr. Res. (IF 3.6) Pub Date : 2024-03-21 Sabrina Ravaglia, Simone Gana, Enza Maria Valente
Glycogen storage disease type V (GSDV, MIM #232600) is an autosomal recessive metabolic myopathy characterized by episodic exercise intolerance, cramps, and myalgias. GSDV is caused by biallelic pathogenic variants in the PYGM gene, encoding for a glycogen phosphorylase that breaks glucose from glycogen in the muscle. The common clinical picture is a mild, pure myopathy, yet a proportion of patients
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DNA methylation of IFI44L as a potential blood biomarker for childhood-onset systemic lupus erythematosus Pediatr. Res. (IF 3.6) Pub Date : 2024-03-21 Jingwei Wang, Xiqiang Dang, Xiaochuan Wu, Zhongyuan Xiang, Yongzhen Li, Yaqian Fu, Tian Shen
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Monitoring Activity and Gait in Children (MAGIC) using digital health technologies Pediatr. Res. (IF 3.6) Pub Date : 2024-03-21 Junrui Di, Pirinka Georgiev Tuttle, Lukas Adamowicz, Wenyi Lin, Hao Zhang, Dimitrios Psaltos, Jessica Selig, Jiawei Bai, F. Isik Karahanoglu, Paul Sheriff, Vijitha Seelam, Bunmi Williams, Sana Ghafoor, Charmaine Demanuele, Mar Santamaria, Xuemei Cai
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Patterns of infant fecal metabolite concentrations and social behavioral development in toddlers Pediatr. Res. (IF 3.6) Pub Date : 2024-03-20 Hannah E. Laue, Julia A. Bauer, Wimal Pathmasiri, Susan C. J. Sumner, Susan McRitchie, Thomas J. Palys, Anne G. Hoen, Juliette C. Madan, Margaret R. Karagas
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Decreased vascular reactivity associated with increased IL-8 in 6-month-old infants of mothers with pre-eclampsia Pediatr. Res. (IF 3.6) Pub Date : 2024-03-20 Kok Lim Kua, Eli Rhoads, James E. Slaven, Shanique Edwards, David M. Haas, Clement L. Ren, Christina Tiller, Jeffrey Bjerregaard, Laura S. Haneline, Robert S. Tepper
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“Moderate and late preterm infants deserve more attention” Pediatr. Res. (IF 3.6) Pub Date : 2024-03-19 Brian K. Stansfield
Moderate and late preterm infants (i.e., 32–<37 weeks post menstrual age, PMA) represent the most common preterm population and, despite an overall higher risk for morbidities and mortality than infants born at term, often escape the sequelae of complications experienced by extremely preterm infants. Most preterm infants born after 32 weeks PMA will nearly approximate the weight and length of more
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Wearable fiber-free optical sensor for continuous monitoring of neonatal cerebral blood flow and oxygenation Pediatr. Res. (IF 3.6) Pub Date : 2024-03-19 Xuhui Liu, Mehrana Mohtasebi, Pegah Safavi, Faraneh Fathi, Samaneh Rabienia Haratbar, Li Chen, Jin Chen, Henrietta S. Bada, Lei Chen, Elie G. Abu Jawdeh, Guoqiang Yu
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Quantitative EEG and prediction of outcome in neonatal encephalopathy: a review Pediatr. Res. (IF 3.6) Pub Date : 2024-03-19 Sriya Roychaudhuri, Katie Hannon, John Sunwoo, Aisling A. Garvey, Mohamed El-Dib
Abstract Electroencephalogram (EEG) is an important biomarker for neonatal encephalopathy (NE) and has significant predictive value for brain injury and neurodevelopmental outcomes. Quantitative analysis of EEG involves the representation of complex EEG data in an objective, reproducible and scalable manner. Quantitative EEG (qEEG) can be derived from both a limited channel EEG (as available during
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Overexpression of miR-22-3p and miR-29c-3p in CFU-Hill colonies is related to senescence process among children with low birth weight Pediatr. Res. (IF 3.6) Pub Date : 2024-03-18 Paula R. P. Souza, Fernanda Thomazini, Livia V. Souza, Carla L. Freitas, Maria do Carmo Franco