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Correction: Individualized estimation of arterial carbon dioxide partial pressure using machine learning in children receiving mechanical ventilation BMC Pediatr. (IF 2.4) Pub Date : 2024-04-25 Hye-Ji Han, Bongjin Lee, June Dong Park
Correction: BMC Pediatr 24, 149 (2024) https://doi.org/10.1186/s12887-024-04642-0 Following publication of the original article [1], the authors would like to correct the IRB approval number from “H-2307-160-1452” to “H-2207-180-1344”. Han HJ, Lee B, Park JD. Individualized estimation of arterial carbon dioxide partial pressure using machine learning in children receiving mechanical ventilation. BMC
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Identifying the most representative actigraphy variables reflecting standardized hand function assessments for remote monitoring in children with unilateral cerebral palsy BMC Pediatr. (IF 2.4) Pub Date : 2024-04-25 Youngsub Hwang, Jeong-Yi Kwon
Accurate assessment of physical activity and motor function in children with cerebral palsy is crucial for determining the effectiveness of interventions. This study aimed to investigate the correlation between real-world activity monitoring outcomes and in-laboratory standardized hand function assessments in children with unilateral cerebral palsy. Actigraphy data were collected over 3 days from children
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The current clinical landscape of neonatal respiratory failure in Jiangsu Province of China: patient demographics, NICU treatment interventions, and patient outcomes BMC Pediatr. (IF 2.4) Pub Date : 2024-04-25 Na Wang, Ke-Yu Lu, Shan-Yu Jiang, Hong-Wei Wu, Rui Cheng, Zhao-Jun Pan, Huai-Yan Wang
Neonatal respiratory failure (NRF) is a serious condition that often has high mortality and morbidity, effective interventions can be delivered in the future by identifying the risk factors associated with morbidity and mortality. However, recent advances in respiratory support have improved neonatal intensive care units (NICUs) care in China. We aimed to provide an updated review of the clinical profile
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Identification of a novel GNAS mutation in a family with pseudohypoparathyroidism type 1A BMC Pediatr. (IF 2.4) Pub Date : 2024-04-25 Fabio Sippelli, Silvana Briuglia, Chiara Ferraloro, Anna Paola Capra, Emanuele Agolini, Tiziana Abbate, Giorgia Pepe, Tommaso Aversa, Malgorzata Wasniewska, Domenico Corica
Pseudohypoparathyroidism (PHP) is caused by loss-of-function mutations at the GNAS gene (as in the PHP type 1A; PHP1A), de novo or inherited at heterozygous state, or by epigenetic alterations at the GNAS locus (as in the PHP1B). The condition of PHP refers to a heterogeneous group of disorders that share common clinical and biological features of PTH resistance. Manifestations related to resistance
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Comparison of the efficacy of parent-mediated NDBIs on developmental skills in children with ASD and fidelity in parents: a systematic review and network meta-analysis BMC Pediatr. (IF 2.4) Pub Date : 2024-04-25 Yuling Ouyang, Junyan Feng, Tiantian Wang, Yang Xue, Zakaria Ahmed Mohamed, Feiyong Jia
Recently, studies on behavioral interventions for autism have gained popularity. Naturalistic Developmental Behavior Interventions (NDBIs) are among the most effective, evidence-based, and widely used behavior interventions for autism. However, no research has been conducted on which of the several NDBI methods is most effective for parents and children with autism spectrum disorders. Therefore, we
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Control of blood pressure in hypertensive children and adolescents assessed by ambulatory blood pressure monitoring BMC Pediatr. (IF 2.4) Pub Date : 2024-04-25 Kevalin Vigraijaroenying, Kwanchai Pirojsakul, Poomiporn Katanyuwong, Kanchana Tangnararatchakit, Pawaree Saisawat, Songkiat Chantarogh, Witchuri Paksi, Uthen Bunmee
There have been few studies evaluating the control of hypertension (HT) in children. This study aimed to assess the control of HT using ambulatory blood pressure monitoring (ABPM) and to compare the parameters between the uncontrolled HT and controlled HT groups. Hypertensive patients aged ≥ 5 years who underwent ABPM to assess the control of HT were enrolled. Demographics, office blood pressure (BP)
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Parents’ and neonatal healthcare professionals’ views on barriers and facilitators to parental presence in the neonatal unit: a qualitative study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-24 Stephanie Vanessa Schmid, Christine Arnold, Sophie Jaisli, Benedikt Bubl, Erika Harju, André Kidszun
Parent and infant separation in the neonatal unit is associated with adverse health outcomes. Family-integrated care has several advantages and the potential to reduce these adverse outcomes but requires parental presence. This study aimed to explore the views of parents and neonatal healthcare professionals (nHCPs) on barriers and facilitators to parental presence in a Swiss neonatal unit and to identify
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Association between quality and quantity of carbohydrate intake with selected anthropometric indices among primary school girls in Kerman city, Iran: a cross-sectional study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-24 Nooshin Jannati, Reyhaneh Mohammadi-Faez, Mohammad Reza Mahmoodi, Leila Azadbakht
The school-age is a crucial period of physical and cognitive growth, which requires an assessment of dietary intake and its influence on body weight and height. This study aims to determine the association between the quality and quantity of carbohydrate intake with selected anthropometric indices in primary school girls in Kerman City, Iran. This cross-sectional study was conducted on 330 primary
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Spatial disparity and associated factors of diarrhea among under-five children in Rwanda: a multilevel logistic regression analysis BMC Pediatr. (IF 2.4) Pub Date : 2024-04-24 Abiyu Abadi Tareke, Sebwedin Surur Jemal, Getahun Dejene Yemane, Hamdi Fekredin Zakaria, Enyew Woretaw Shiferaw, Anaclet Ngabonzima
Diarrhea, defined as three or more loose stool per day, is a major cause of child mortality. Exploring its spatial distribution, prevalence, and influencing factors is crucial for public health decision and targeted interventions. This study aimed to investigate these aspects using 2019 Rwanda demographic health survey data. A total 7,978 (weighted) under-five children were included in this study.
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Analysis and prediction of nutritional outcome of patients with pediatric inflammatory bowel disease from Bahrain BMC Pediatr. (IF 2.4) Pub Date : 2024-04-24 Hasan M. Isa, Masooma Mohamed, Ahmed Alsaei, Zahra Isa, Enjy Khedr, Afaf Mohamed, Haitham Jahrami
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease that causes anorexia, malabsorption, and increased energy requirements. Childhood IBD can significantly impact nutritional status and future health. This study aimed to analyze the nutritional status of patients with pediatric IBD at presentation and during follow-up and to identify predictors of nutritional outcome. This retrospective
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Incidental finding of thyroglossal duct cyst in a neonate during endotracheal intubation: a case report BMC Pediatr. (IF 2.4) Pub Date : 2024-04-23 Emanuele Trovalusci, Carlo Pizzolon, Silvia Tesser, Stefano Doratiotto, Dalia Gobbi, Paola Midrio
Thyroglossal Duct Cyst (TDC) is a common lesion of the midline neck, originating from an incomplete involution of the thyroglossal duct. It is typically observed in pre-scholar patients and surgery is the treatment of choice to prevent infections. Here reported a case of incidental diagnosis in a newborn patient. a 3-week-old male baby was admitted to our hospital for weight loss and projectile vomits
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Evidence-based recommendations for delivering the diagnosis of X & Y chromosome multisomies in children, adolescents, and young adults: an integrative review BMC Pediatr. (IF 2.4) Pub Date : 2024-04-22 Kirsten A. Riggan, Kelly E. Ormond, Megan A. Allyse, Sharron Close
The diagnosis of supernumerary X & Y chromosome variations has increased following the implementation of genetic testing in pediatric practice. Empirical evidence suggests that the delivery of the diagnosis has a lasting impact on how affected individuals and their parents perceive and adapt to the diagnosis. The purpose of this review is to synthesize the literature to obtain useful recommendations
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The impact of combined administration of surfactant and intratracheal budesonide compared to surfactant alone on bronchopulmonary dysplasia (BPD) and mortality rate in preterm infants with respiratory distress syndrome: a single-blind randomized clinical trial BMC Pediatr. (IF 2.4) Pub Date : 2024-04-20 Asghar Marzban, Samira Mokhtari, Pouria Tavakkolian, Reza Mansouri, Nahid Jafari, Azam Maleki
Respiratory distress syndrome (RDS) is one of the most important and common disorders among premature infants. This study aimed to compare the effect of the combination of surfactant and budesonide with surfactant alone on Bronchopulmonary dysplasia (BPD) and mortality rate among premature infants with RDS. An outcome assessor-blind randomized clinical trial was conducted on 134 premature infants with
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Association between body mass index and tic disorders in school-age children BMC Pediatr. (IF 2.4) Pub Date : 2024-04-20 Lu Bai, Xia Wang, Ruijie Niu, Mengchuan Zhao, Ziwei Zhao, Pengyu Jia, Suzhen Sun
To explore the relationship between body mass index (BMI ) and the severity of tic disorders (TDs) in children 6–14 years old. A total of 86 children diagnosed with TDs in a hospital between Jan. 2023 and Sept. 2023 were collected by convenient sampling method, and the general data and TD-specific data were collected and analyzed. Univariate analysis showed that patients with different Yale Global
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Determinants of externally visible birth defects among perinatal deaths at Adama Comprehensive Specialized Hospital: a case-control study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-20 Husen Aman, Seifadin Ahmad, Getahun Chala, Mekbeb Afework
Birth defects (BDs) are the major causes of infant morbidity and mortality in both developed and developing countries. Regardless of their clinical importance, few studies on predisposing factors have been conducted in Ethiopia. However, due to a lack of advanced diagnostic materials, we only considered the externally visible BDs. To assess the determinants of externally visible birth defects among
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Correlation of gestational age and age at death in sudden infant death syndrome: another pointer to the role of critical developmental period? BMC Pediatr. (IF 2.4) Pub Date : 2024-04-19 Malgorzata Habich, Piotr Zielenkiewicz, Leszek Paczek, Pawel Szczesny
Filiano and Kinney proposed a triple-risk model for the sudden infant death syndrome (SIDS) that involves the intersection of three risks: (1) a vulnerable infant, (2) a critical developmental period in homeostatic control, and (3) an exogenous stressor(s). The primary evidence for the role of a critical developmental period in SIDS etiology is the peak of cases around the third month of life. Independently
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Evaluating a web-based training curriculum for disseminating best practices for the care of newborns with neonatal opioid withdrawal syndrome in a rural hospital, the NOWS-NM Program BMC Pediatr. (IF 2.4) Pub Date : 2024-04-19 Heather Pratt-Chavez, Heidi Rishel Brakey, Sarah G. Sanders, Juhee Patel, Tim Ozechowski, Chloe Stoffel, Andrew L. Sussman, Jessie Marquez, David R. Smith, Alberta S. Kong
The incidence of neonatal opiate withdrawal syndrome (NOWS) in the US has grown dramatically over the past two decades. Many rural hospitals not equipped to manage these patients transfer them to hospitals in bigger cities. We created a curriculum, the NOWS-NM Program, a web-based curriculum training in best practices. To evaluate the curriculum, we conducted pre- and post-surveys of NOWS knowledge
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Seizures in febrile children with SARS-CoV-2 infection: clinical features, short-term follow-up BMC Pediatr. (IF 2.4) Pub Date : 2024-04-17 Jipeng Jiang, Zhengsong Shen, Jie Cao
As the Omicron variant of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerges, the neurological manifestations correlated with this epidemic have garnered increasing attention. This study was primarily intended to compare seizures in febrile children with and without SARS-CoV-2 infection and to conduct short-term follow-up of the SARS-CoV-2-infected patients. Retrospective analysis
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The effect of maternal voice and non-nutritional sucking on repeated procedural pain of heel prick in neonates: a quasi-experimental study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-16 Yushuang Chen, Leshan Zhou, Yanjuan Tan
Neonates in the neonatal intensive care unit undergo frequent painful procedures. It is essential to reduce pain using safe and feasible methods. To evaluate the effects of non-nutritional sucking, mother’s voice, or non-nutritional sucking combined with mother’s voice on repeated procedural pain in hospitalized neonates. A quasi-experimental study was conducted in which 141 neonates were selected
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Nomogram for predicting early hypophosphatemia in term infants BMC Pediatr. (IF 2.4) Pub Date : 2024-04-16 Wan Tao, Shina Zhan, Yingjie Shen, Tianjiao Zhao, Feitian Li, Miao Gao, Tingting Yang, Jinqian Yu
Physiological processes rely on phosphate, which is an essential component of adenosine triphosphate (ATP). Hypophosphatasia can affect nearly every organ system in the body. It is crucial to monitor newborns with risk factors for hypophosphatemia and provide them with the proper supplements. We aimed to evaluate the risk factors and develop a nomogram for early hypophosphatemia in term infants. We
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Critically ill children with SARS-COV-2 Omicron infection at a national children medical center, Guangdong, China BMC Pediatr. (IF 2.4) Pub Date : 2024-04-15 Fen Lin, Dao-Ju Jiang, Song Zhang, Zhe Yang, Hua-Song Zeng, Zhi-Ping Liu, Li-Ye Yang
SARS-CoV-2 infection is described as asymptomatic, mild, or moderate disease in most children. SARS-CoV-2 infection related death in children and adolescents is rare according to the current reports. COVID-19 cases increased significantly in China during the omicron surge, clinical data regarding pediatric critical patients infected with the omicron variant is limited. In this study, we aim to provide
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Systemic lupus erythematosus combined with Wilson’s disease: a case report and literature review BMC Pediatr. (IF 2.4) Pub Date : 2024-04-15 Zhenle Yang, Qian Li, Suwen Liu, Zihan Zong, Lichun Yu, Shuzhen Sun
Systemic lupus erythematosus (SLE) and Wilson’s disease (WD) are both systemic diseases that can affect multiple organs in the body. The coexistence of SLE and WD is rarely encountered in clinical practice, making it challenging to diagnose. We present the case of a 9-year-old girl who initially presented with proteinuria, haematuria, pancytopenia, hypocomplementemia, and positivity for multiple autoantibodies
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The effect of respiratory muscle training on children and adolescents with cystic fibrosis: a systematic review and meta-analysis BMC Pediatr. (IF 2.4) Pub Date : 2024-04-15 WenQian Cai, Meng Li, Yi Xu, Mei Li, JiaNan Wang, YaHui Zuo, JinJin Cao
Cystic fibrosis is a chronic genetic disease that can affect the function of the respiratory system. Previous reviews of the effects of respiratory muscle training in people with cystic fibrosis are uncertain and do not consider the effect of age on disease progression. This systematic review aims to determine the effectiveness of respiratory muscle training in the clinical outcomes of children and
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Association between dietary selenium and zinc intake and risk of dilated cardiomyopathy in children: a case-control study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-11 Maryam Aryafar, Mohammad Mahdavi, Hossein Shahzadi, Yeganeh Rajabpour Ranjbar, Mohammad Hassan Sohouli, Sina Afzal, Asal Neshatbini Tehrani, Danial Fotros, Ghazal Daftari
Dilated cardiomyopathy (DCMP) is characterized by the enlargement and weakening of the heart and is a major cause of heart failure in children. Infection and nutritional deficiencies are culprits for DCMP. Zinc is an important nutrient for human health due to its anti-oxidant effect that protects cell against oxidative damage. This case-control study aimed to investigate the relationship between dietary
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The timing of minimally invasive surgery for prenatally diagnosed choledochal cysts BMC Pediatr. (IF 2.4) Pub Date : 2024-04-11 Shiwen Pan, Wei Li, Huan Chen, Changgui Lu
There are no clear evidence-based recommendations concerning when patients with prenatally diagnosed choledochal cysts (CCs) should undergo surgery. This study was primarily designed to explore the proper timing of minimally invasive surgery for prenatally diagnosed CC patients. Seventy-three patients with prenatally diagnosed CC were enrolled in this study and divided into 4 subgroups according to
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Delineating morbidity patterns in preterm infants at near-term age using a data-driven approach BMC Pediatr. (IF 2.4) Pub Date : 2024-04-11 Octavia-Andreea Ciora, Tanja Seegmüller, Johannes S. Fischer, Theresa Wirth, Friederike Häfner, Sophia Stoecklein, Andreas W. Flemmer, Kai Förster, Alida Kindt, Dirk Bassler, Christian F. Poets, Narges Ahmidi, Anne Hilgendorff
Long-term survival after premature birth is significantly determined by development of morbidities, primarily affecting the cardio-respiratory or central nervous system. Existing studies are limited to pairwise morbidity associations, thereby lacking a holistic understanding of morbidity co-occurrence and respective risk profiles. Our study, for the first time, aimed at delineating and characterizing
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Predicting chronological age of 14 or 18 in adolescents: integrating dental assessments with machine learning BMC Pediatr. (IF 2.4) Pub Date : 2024-04-10 Shihui Shen, Yibo Guo, Jiaxuan Han, Meizhi Sui, Zhuojun Zhou, Jiang Tao
Age estimation plays a critical role in personal identification, especially when determining compliance with the age of consent for adolescents. The age of consent refers to the minimum age at which an individual is legally considered capable of providing informed consent for sexual activities. The purpose of this study is to determine whether adolescents meet the age of 14 or 18 by using dental development
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Resistance training presents beneficial effects on bone development of adolescents engaged in swimming but not in impact sports: ABCD Growth Study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-09 Ricardo R. Agostinete, André O. Werneck, Pedro H. Narciso, Esther Ubago-Guisado, Manuel J. Coelho-e-Silva, Renata M. Bielemann, Luis Alberto Gobbo, Bruna Turi Lynch, Romulo Araújo Fernandes, Dimitris Vlachopoulos
Sports practice during adolescence is important to enhance bone development, although it may provide different effects depending on the mechanical impact present in the sport. Besides, resistance training (RT) may also induce bone changes directly (via muscle contractions) and indirectly (via myokines). However, there have been no studies analyzing the longitudinal influence of engaging in sport with
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Chronic stridor in a toddler after ingestion of a discharged button battery: a case report BMC Pediatr. (IF 2.4) Pub Date : 2024-04-06 Zoe S. Oftring, Doortje M. Mehrtens, Julian Mollin, Eckard Hamelmann, Sebastian Gaus
Button battery (BB) ingestions (BBI) are increasingly prevalent in children and constitute a significant, potentially life-threatening health hazard, and thus a pediatric emergency. Ingested BBs are usually charged and can cause severe symptom within 2 h. Discharged BBs ingestion is very rare and protracted symptom trajectories complicate diagnosis. Timely imaging is all the more important. Discharged
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Antibiotic use in infants at risk of early-onset sepsis: results from a unicentric retrospective cohort study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-05 Catalina Morales-Betancourt, Diego Fontiveros-Escalona, Adriana Montealegre-Pomar, Tania Carbayo-Jiménez, María Palomares-Eraso, Concepción de Alba-Romero, Elena Bergón-Sendín, Maria Teresa Moral Pumarega, Carmen Pallás-Alonso
Antibiotic use for early-onset sepsis represents a high percentage of antibiotic consumption in the neonatal setting. Measures to assess infants at risk of early-onset sepsis are needed to optimize antibiotic use. Our primary objective was to assess the impact of a departmental guideline on antibiotic use among term infants with suspected EOS not confirmed, in our neonatal unit. Retrospective cohort
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Growth and endocrinopathies among children with β-Thalassemia major treated at Dubai Thalassemia centre BMC Pediatr. (IF 2.4) Pub Date : 2024-04-05 Rabah Almahmoud, Amal Hussein, Fatheya Al Khaja, Ahmed Farrag Soliman, Hany Dewedar, Zainab Al Shareef, Sarah Mathai
β-Thalassemia major (BTM) is one of the most common hereditary anemias worldwide. Patients suffer from iron overload that results from repeated blood transfusion This in turn leads to multiple organ damage and endocrinopathies. This study aims to assess the prevalence of growth retardation, hypothyroidism, and diabetes mellitus in children and adolescents with BTM treated at Dubai Thalassemia Centre
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Cholangiocarcinoma identified in perforated choledochal cyst in a 3-year-old boy BMC Pediatr. (IF 2.4) Pub Date : 2024-04-05 Lun Yu, Wenli Xiu, Aimei Yue, Xiwei Hao, Zhong Jiang, Jie Wu, Qian Dong
Cholangiocarcinoma in patients with Choledochal cysts is rare in childhood; however, it seriously affects the prognosis of the disease. The key to addressing this situation lies in completely removing the extrahepatic cyst. We herein present a case report of a 3-year-old boy with cholangiocarcinoma associated with a choledochal cyst (CDC). Preoperative 3D simulation, based on CT data, played an important
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Epidermolysis Bullosa: Two rare case reports of COL7A1 and EBS-GEN SEV KRT14 variants with review of literature BMC Pediatr. (IF 2.4) Pub Date : 2024-04-05 Fatma Mabrouk Ali, Jieyu Zhou, Mingyan Wang, Qiuxia Wang, Lulu Sun, Mansour Maulid Mshenga, Hongyan Lu
Bullosa is a rare hereditary skin condition that causes blisters. Genes encoding structural proteins at or near the dermal-epidermal junction are mutated recessively or dominantly, and this is the primary cause of EB. Herein, two Chinese boys were diagnosed with the condition, each with a different variant in a gene that serves as a reference for EB genetic counseling. Skincare significantly impacted
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Reconstitution of oral antibiotic suspensions for paediatric use in households: a cross-sectional study among caregivers of 3–5-year-old children from a selected district, Sri Lanka BMC Pediatr. (IF 2.4) Pub Date : 2024-04-04 Malith Kumarasinghe, Manuj C. Weerasinghe
Reconstitution of oral pediatric antibiotic suspension by primary caregivers plays an essential role in determining the overall health outcome of the child. Incorrect reconstitution techniques could lead to underdosing, overdosing, or introduction of infection. Underdosing could lead to non-resolving infection and antimicrobial resistance. To assess the practice and associated factors on reconstitution
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Erythroferrone and hepcidin levels in children with iron deficiency anemia BMC Pediatr. (IF 2.4) Pub Date : 2024-04-04 Ramazan Dulkadir, Gamze Turna Saltoğlu, Ali Güneş
Iron deficiency anemia remains a significant public health issue in developing countries. The regulation of iron metabolism is primarily controlled by hepcidin, a key regulatory protein. During erythropoiesis, erythroferrone (ERFE), a hormone produced by erythroblasts in response to erythropoietin (EPO) synthesis, mediates the suppression of hepcidin. In this study, it was aimed to determine the correlation
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Effect of play-based intervention on children’s mental status and caregiver involvement during hospitalization: findings from Pakistan BMC Pediatr. (IF 2.4) Pub Date : 2024-04-04 Vardah Noor Ahmed Bharuchi, Muneera A. Rasheed
The nurturing care framework (NCF) encompasses responsive caregiving, health, nutrition, safety and security by parents and other caregivers. It improves health, development and wellbeing of children. A hospital environment can be detrimental to the developmental and emotional needs of children hence NCF can be applied to hospitalized children. The objective was to determine if (i) play stimulation
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Nutritional support during the first week for infants with bronchopulmonary dysplasia and respiratory distress: a multicenter cohort study in China BMC Pediatr. (IF 2.4) Pub Date : 2024-04-03 Huijia Lin, Guannan Bai, Jiajing Ge, Xuefeng Chen, Xinyu He, Xiaolu Ma, Liping Shi, Lizhong Du, Zheng Chen
Bronchopulmonary dysplasia (BPD) is a major complication affecting the survival rate and long-term outcomes of preterm infants. A large, prospective, multicenter cohort study was conducted to evaluate early nutritional support during the first week of life for preterm infants with a gestational age < 32 weeks and to verify nutritional risk factors related to BPD development. A prospective multicenter
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Predictors of neonatal mortality among neonates admitted to the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital, Sidama regional state, Ethiopia BMC Pediatr. (IF 2.4) Pub Date : 2024-04-03 Kefyalew Taye, Yenew Kebede, Desalegn Tsegaw, Worku Ketema
Despite promising efforts, substantial deaths occurred during the neonatal period. According to estimates from the World Health Organization (WHO), Ethiopia is among the top 10 nations with the highest number of neonatal deaths in 2020 alone. This staggering amount makes it difficult to achieve the SDG (Sustainable Development Goals) target that calls for all nations to work hard to meet a neonatal
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Clinical characteristics analysis of pediatric spinal cord injury without radiological abnormality in China: a retrospective study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-03 Renfeng Liu, Qizhi Fan, Jingpeng He, Xin Wu, Wei Tan, Zuyun Yan, Weiguo Wang, Zhiyue Li, You-Wen Deng
This study aims to analyze the clinical characteristics of Chinese children with spinal cord injury (SCI) without radiographic abnormality (SCIWORA) and explore their contributing factors and mechanisms of occurrence. A retrospective analysis was conducted on the clinical data of pediatric patients diagnosed with SCIWORA from January 2005 to May 2020. Epidemiological, etiological, mechanistic, therapeutic
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Family systems approaches in pediatric obesity management: a scoping review BMC Pediatr. (IF 2.4) Pub Date : 2024-04-02 Natasha Wills-Ibarra, Keryn Chemtob, Heather Hart, Francesca Frati, Keeley J Pratt, Geoff DC Ball, Andraea Van Hulst
Family-based obesity management interventions targeting child, adolescent and parental lifestyle behaviour modifications have shown promising results. Further intervening on the family system may lead to greater improvements in obesity management outcomes due to the broader focus on family patterns and dynamics that shape behaviours and health. This review aimed to summarize the scope of pediatric
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Evaluation of disease severity and prediction of severe cases in children hospitalized with influenza A (H1N1) infection during the post-COVID-19 era: a multicenter retrospective study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-02 Hai-Feng Liu, Xiao-Zhong Hu, Rong-Wei Huang, Zheng-Hong Guo, Jin-Rong Gao, Mei Xiang, Rui Lu, Deng Ban, Cong-Yun Liu, Ya-Yu Wang, Wang Li, Yin Li, Yun-Jie Guo, Quan Lu, Hong-Min Fu
The rebound of influenza A (H1N1) infection in post-COVID-19 era recently attracted enormous attention due the rapidly increased number of pediatric hospitalizations and the changed characteristics compared to classical H1N1 infection in pre-COVID-19 era. This study aimed to evaluate the clinical characteristics and severity of children hospitalized with H1N1 infection during post-COVID-19 period,
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Sustained acute kidney injury as an independent risk factor for neurodevelopmental and growth outcomes in a single NICU center BMC Pediatr. (IF 2.4) Pub Date : 2024-04-02 Chen-Wei Yen, Ming-Chou Chiang, Shih-Ming Chu, Hsiao-Chin Wang, Li-Chun Wu, Po-Cheng Yen, Mei-Ching Yu
Acute kidney injury (AKI) is commonly seen in neonatal intensive care units (NICUs) and is potentially associated with adverse prognoses in later stages of life. Our study evaluated the impact of sustained AKI (SAKI) on both neurodevelopmental impairment (NDI) and early growth restriction (EGR) in neonates. This case-control study retrospectively analyzed the medical records of neonates diagnosed with
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Recurrent myocardial injury in a de novo SON mutation ZTTK syndrome patient: a case report BMC Pediatr. (IF 2.4) Pub Date : 2024-04-02 Jia Na, Lang Cui, Zhen Zhen, Xi Chen, Qirui Li, Lu Gao, Yue Yuan
Zhu-Tokita-Takenouchi-Kim syndrome (ZTTK syndrome) is a severe multi-systemic developmental disorder, caused by variants in the SON gene. A patient diagnosed with ZTTK syndrome who carried a de novo SON mutation and exhibited recurrent myocardial injury was described in this case. A 7-year-old girl was admitted to the Cardiology Department of Beijing Children’s Hospital in November 2019 due to myocardial
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The impact of non-pharmaceutical interventions on community non-SARS-CoV-2 respiratory infections in preschool children BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Bianca Klee, Sophie Diexer, Johannes Horn, Susan Langer, Marie Wende, Diego Ortiz, Agata Bielecka, Till Strowig, Rafael Mikolajczyk, Cornelia Gottschick
Effects of non-pharmaceutical interventions during the pandemic were mainly studied for severe outcomes. Among children, most of the burden of respiratory infections is related to infections which are not medically attended. The perspective on infections in the community setting is necessary to understand the effects of the pandemic on non-pharmaceutical interventions. In the unique prospective LoewenKIDS
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Next-generation sequencing based newborn screening and comparative analysis with MS/MS BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Guosong Shen, Wenwen Li, Yaqin Zhang, Lyuyan Chen
Newborn screening (NBS), such as tandem mass spectrometry (MS/MS), may yield false positive/negative results. Next-generation sequencing (NGS) has the potential to provide increased data output, efficiencies, and applications. This study aimed to analyze the types and distribution of pathogenic gene mutations in newborns in Huzhou, Zhejiang province, China and explore the applicability of NGS and MS/MS
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Evaluation of cardiac autonomic dysfunctions in children with type 1 diabetes mellitus BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Davut Gözüküçük, Berkut A. İleri, Serra Karaca Başkan, Ece Öztarhan, Dilek Güller, Hasan Önal, Kazım Öztarhan
Cardiovascular autonomic neuropathy (CAN) is a serious complication of diabetes, impacting the autonomic nerves that regulate the heart and blood vessels. Timely recognition and treatment of CAN are crucial in averting the onset of cardiovascular complications. Both clinically apparent autonomic neuropathy and subclinical autonomic neuropathy, particularly CAN pose a significant risk of morbidity and
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Factors associated with damages and repair costs of reusable flexible bronchoscopes in pediatrics in China BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Ruixue Hu, Yanhua Chen, Sixin Jiang, Ting Hu, Juanli Huang, Lu Zhang, Wei Pan, Liangying Yi, Yan Huang
Frequent repairs of pediatric flexible bronchoscopes can lead to a huge financial burden for the hospital. This study aimed to investigate the common causes of the failures in pediatric flexible bronchoscopes and propose the measures to prevent the failures. This was a retrospective study. We collected repair information of the pediatric flexible bronchoscopes reprocessed in the Department of Sterile
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Clinical features of intussusception in children secondary to small bowel tumours: a retrospective study of 31 cases BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Li Wang, Hanwen Zhang, Dayong Wang, Qiulong Shen, Liuming Huang, Tingting Liu
Summarizing the clinical features of children with intussusception secondary to small bowel tumours and enhancing awareness of the disease. Retrospective summary of children with intussusception admitted to our emergency department from January 2016 to January 2022, who underwent surgery and were diagnosed with small bowel tumours. Summarize the types of tumours, clinical presentation, treatment, and
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Familial dilated cardiomyopathy in a child: a case report BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Ali Ismail, Dima Khreis, Amani Assaad, Marianne Nimah Majdalani
Dilated cardiomyopathy (DCM) commonly leads to heart failure (HF) and represents the most common indication for cardiac transplantation in the pediatric population. Clinical manifestations of DCM are mainly the symptoms of heart failure; it is diagnosed by EKG, chest x-ray and echocardiography. For the idiopathic and familial diseases cases of DCM, there are no definite guidelines for treatment in
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Multicenter registry of pediatric inflammatory bowel disease from a developing country BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Pornthep Tanpowpong, Settapong Jitwongwai, Teera Kijmassuwan, Hansa Sriphongphankul, Seksit Osatakul, Alisara Damrongmanee, Nuthapong Ukarapol, Suporn Treepongkaruna
Despite the rising incidence of pediatric inflammatory bowel disease (PIBD) globally, multicenter collaborative studies of PIBD children among developing countries remain sparse. We therefore aimed to define the initial presentation and short-term outcomes of Thai children with PIBD from a multicenter registry. Four teaching hospitals participated in this study. A diagnosis of PIBD requires gastrointestinal
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Delayed onset of neonatal compartment syndrome associated with compound fetal presentation BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Nicholas Manini, Hayato Unno
Neonatal compartment syndrome, although rare, has a classic presentation with sentinel skin findings and development of swelling, erythema, and tenderness of the affected extremity. Neonatal compartment syndrome requires prompt surgical intervention to preserve the affected limb and ensure its normal growth and development. Our patient was born at term via vaginal delivery complicated by a compound
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Unusual presentation of miliary tuberculosis in a 12-year-old girl: a case report BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Mahsa Kamali, Mohammad Reza Navaeifar, Ali Abbaskhanian, Azin Hajialibeig, Farnaz Godazandeh, Mahsa Salehpour, Mohammad Sadegh Rezai
Miliary tuberculosis (TB) is a lethal hematogenous spread form of mycobacterium tuberculosis with approximately 15–20% mortality rate in children. The present report highlights the clinical manifestations of an unusual presentation of miliary tuberculosis in a 12-year-old girl. In this case, extensive lung involvement was presented despite the absence of respiratory symptoms. Also, some central hypo-intense
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Exploring the complex dynamics of BMI, age, and physiological indicators in early adolescents BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Ning Ding, Suyun Li, Han Zhou, Zhenchuang Tang, Tianlin Gao, Meina Tian, Changqing Liu, Xiaoyan Luo, Hongtong Chen, Lianlong Yu, Yao Chen, Li Yang, Lichao Zhu
To investigate the relationship between body mass index (BMI) and blood biochemical indicators in early adolescence, and to provide ideas for early prevention of diseases and explore possible disease-related predictors. 3125 participants aged 10 ∼ 14 years were selected from China from the survey of “China Nutrition and Health Surveillance ( 2016 ∼ 2017 ) “. Employing advanced statistical methods,
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Stabilizing time and its predictors among 1–59 months old children managed for severe acute malnutrition during the humanitarian crisis in Tigray regional state of Ethiopia, 2023: a prospective cohort study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Wagnew Tesfay, Mebrahtu Abay, Berhane Fseha Teklehaimanot, Ataklti Gebremedhin
Higher rate of acute malnutrition is observed in emergencies compared to non-emergency settings and severe acute malnutrition upsurges alarmingly and become deadly in humanitarian crises due to lack of food, lack of quality water supply and insufficient healthcare. Research is one learning tool by identifying strength and areas of improvement. However, little is known about outcomes of therapeutic
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Effects of sleep-disordered breathing on serum lipid levels in children:a case control study BMC Pediatr. (IF 2.4) Pub Date : 2024-04-01 Lei Lei, XiaoYun Zhang, Binbin Wang, Fei Lei, Li Dai, Xiaoru Sun, Yu Zhao, Ping Zhu, Jian Zou
Sleep-disordered breathing (SDB) during childhood is common and includes a range of breathing abnormalities that range from primary snoring (PS) to obstructive sleep apnea syndrome (OSAS).Studies have shown that not only OSAS, but also PS, which is originally considered harmless, could cause cardiovascular, cognitive, behavioral, and psychosocial problems. Many researches are focused on the relation
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Incidence and development of validated mortality prediction model among asphyxiated neonates admitted to neonatal intensive care unit at Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Northwest Ethiopia, 2021: retrospective follow-up study BMC Pediatr. (IF 2.4) Pub Date : 2024-03-28 Yibeltal Shitu Tegegne, Tilahun Yemanu Birhan, Habtamu Takele, Fantahun Ayenew Mekonnen
Perinatal asphyxia is failure to maintain normal breathing at birth. World Health Organization indicates that perinatal asphyxia is the third major cause of neonatal mortality in developing countries accounting for 23% of neonatal deaths every year. At global and national level efforts have done to reduce neonatal mortality, however fatalities from asphyxia remains high in Ethiopia (24%). And there
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Optimizing care for children with difficult-to-treat and severe asthma through specialist paediatric asthma centres: expert practical experience and advice BMC Pediatr. (IF 2.4) Pub Date : 2024-03-27 M. W. Pijnenburg, S. Rubak, H. O. Skjerven, S. Verhulst, V. Elenius, C. Hugen, O. Jauhola, C. Kempeneers, E. Melén, T. Reier Nilsen, N. W. Rutjes, M. Ruotsalainen, H. Schaballie, A. M. Zwitserloot, M. Proesmans, M. J. Mäkelä
Severe asthma in children carries an unacceptable treatment burden, yet its rarity means clinical experience in treating it is limited, even among specialists. Practical guidance is needed to support clinical decision-making to optimize treatment for children with this condition. This modified Delphi convened 16 paediatric pulmonologists and allergologists from northern Europe, all experienced in treating
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Screening for symptoms of childhood traumatic stress in the primary care pediatric clinic BMC Pediatr. (IF 2.4) Pub Date : 2024-03-27 Kristine A. Campbell, Kara A. Byrne, Brian L. Thorn, Lindsay Shepard Abdulahad, R. Neal Davis, Lisa L. Giles, Brooks R. Keeshin
Childhood traumatic experiences may result in post-traumatic stress disorder. Although pediatricians are encouraged to address these traumas in clinical encounters, measures of childhood traumatic stress have not been adopted by primary care clinicians. In this study, we describe the feasibility and potential utility of the UCLA Brief Screen, a validated screener for childhood traumatic stress symptoms
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Evaluating the association between duration of breastfeeding and fine motor development among children aged 20 to 24 months in Butajira, Ethiopia: a case-control study BMC Pediatr. (IF 2.4) Pub Date : 2024-03-27 Rediate Shiferaw, Robel Yirgu, Yalemwork Getnet
A Suitable environment and proper child nutrition are paramount to a child’s physical and mental development. Different environmental factors contribute to proper child development. Breast milk is an important source of nutrition during the early years of life and contains essential nutrients that are the building blocks for growth and development. To assess the association between the duration of
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Exploring the diagnostic value of ultrasound radiomics for neonatal respiratory distress syndrome BMC Pediatr. (IF 2.4) Pub Date : 2024-03-25 Weiru Lin, Junxian Ruan, Zhiyong Liu, Caihong Liu, Jianan Wang, Linjun Chen, Weifeng Zhang, Guorong Lyu
Neonatal respiratory distress syndrome (NRDS) is a prevalent cause of respiratory failure and death among newborns, and prompt diagnosis is imperative. Historically, diagnosis of NRDS relied mostly on typical clinical manifestations, chest X-rays, and CT scans. However, recently, ultrasound has emerged as a valuable and preferred tool for aiding NRDS diagnosis. Nevertheless, evaluating lung ultrasound